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Samylin Liver Supplement for Dogs

  • Large Breed » 5.3g Sachet (Pack of 30) £59.84
  • Large Breed » Tablets (Pack of 30) £59.12
  • Medium Breed » 4g Sachet (Pack of 30) £49.70
  • Medium Breed » Tablets (Pack of 30) £48.69
  • Small Breed » 1g Sachet (Pack of 30) £25.31
  • Small Breed » Tablets (Pack of 30) £25.29

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£25.29 to £59.84


Samylin is a food supplement used where there are concerns regarding liver function. Samylin contains SAMe which is a precursor of glutathione. This is known to be required by the liver and elevated levels are able to increase the effective functioning of the liver. Other ingredients include the antioxidant and thiol donor Silybin (found in Milk Thistle), Vitamin E and Vitamin C. Samylin is used at a rate of one sachet per 5kg of bodyweight per day, mixed with food.

Product Information

Small Breed - For cats and dogs up to 10kg

Medium Breed - For dogs between 11kg and 30kg

Large Breed - For dogs between 30kg and 40kg

Administration Rate for Tablets

Weight Administration Rate
Cats and Dogs under 5kg 1 x small breed Tablet daily
Dogs 5-10kg 2 x small breed Tablets daily
Dogs 11-20kg 1 x medium breed Tablet daily
Dogs 20-30kg 2 x medium breed Tablets daily
Dogs 30-40kg 2 x large breed Tablets daily

Administration Rate for Sachets

Cats and Dogs under 5kg 1 sachet daily small breed
Dogs 5-10kg 2 sachets daily small breed
Dogs 11-20kg: 1 medium breed sachet daily
Dogs 20-30kg: 2 medium breed sachets daily
Dogs 30-40kg: 2 large breed sachets daily

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Reviews of Samylin Liver Supplement for Dogs

Read our customers' reviews of Samylin Liver Supplement for Dogs

Questions & Answers for Samylin Liver Supplement for Dogs

Below are some recent questions we've received regarding Samylin Liver Supplement for Dogs, including answers from our team.

Ask Your Own Question

Wrong product

16th May 2016
Patricia Hickey
  • VioVet Customer Since: May 2016
  • From: Greater Manchester, United Kingdom

Can I get a refund then

John Cousins
  • Veterinary Surgeon

If you accidentally order the wrong product, you can return it to us (at your own expense). It it arrives back to us and you have taken appropriate care with the product, we will be happy to refund your full purchase price.

Use in cats?

16th May 2016
Patricia Hickey
  • VioVet Customer Since: May 2016
  • From: Greater Manchester, United Kingdom

I've just ordered Samylin Liver Supplement for dogs is it okay to give to cats because my have it to me last time

John Cousins
  • Veterinary Surgeon

Samylin is marketed just for dogs by the manufacturer and so we have to follow this lead and advise that it is intended just for dogs. However all the active ingredients are sometimes used in cats and the main ingredient is indeed regarded as helpful and very safe for cats with liver trouble. If you choose to use it in a cat this is up to you, but I think it would be safe.

Feed with other supplements

27th Apr 2016
Chen Chi (josefa) Hsu
  • VioVet Customer Since: June 2015
  • From: , Hong Kong

hi, doc, i bot samylin for years and always mixed with food and other supplements like fish oil, probiotic and vitamin c. my dog has been ok and didnt have any stomach upset. i am wondering if this way of feeding is ok and any restriction when feeding samylin. thank you!!

John Cousins
  • Veterinary Surgeon

Samylin is usually given with food and it can certainly be given with the other supplements you mention. I do not see any problem with you doing this. There are some supplements which can potentially cause trouble in themselves, particularly those containing vitamins A or D. Overdosing those can cause trouble. As long as you avoid that and you generally only give supplements in the quantities recommended by the manufacturer, it should be safe. You might not need to be giving so many supplements; most dogs do not need them if the general diet is good quality. However this is up to you. Obviously check with your own vet if you are unsure about anything, or about your dogs medical conditions generally.

Pill or with Guggum whether powder?

21st Mar 2016
Min Jung Kwon
  • VioVet Customer Since: March 2016
  • From: 50, Hugok-ro, paiu-si, Gyeonggi-, Korea, Democratic People's Republic of

Book he slways reply Thank you. ^ - ^
Cognitive pills to slitting my son were 8.5kg. saemillil I just had to order
the breed. Medium or pink powder l wan na
get it a pill !!!
And chopped them up, and equal benefits
Would like to know if we may.
♧ I am Korean. not good at English so
please understand !!! Thank you.

John Cousins
  • Veterinary Surgeon

You can give tablet or powder. You can split the tablets.


20th Mar 2016
Min Jung Kwon
  • VioVet Customer Since: March 2016
  • From: 50, Hugok-ro, paiu-si, Gyeonggi-, Korea, Democratic People's Republic of

Because dog is higher levels of liver saemilli
to be eating falls was bad liver numbers, Could you recommend if you have anything
better. We ask, please! "please"

John Cousins
  • Veterinary Surgeon

Samylin is regarded as one of the best liver supplements and it is likely to be as good as any supplement of this type. Some liver conditions can respond to antibiotics or steroids or other prescription medication, so your own vet can advise you on these. Ideally you need to make a precise diagnosis and then treat that condition as well as you can. Raised liver enzyme levels usually indicates liver damage, but tells you nothing about why that damage has occurred. This should be investigated. Sometimes it can be caused by a bad reaction to other medication which has been given, so if your dog is on any other medication which could be causing the damage, you should consider stopping that immediately.

Samylin tablets

8th Jan 2016
MRS S POUND (dupon2141)
  • VioVet Customer Since: February 2013
  • From: SURREY, United Kingdom

Are these given on an empty tummy as there are no details in the box.. I assume the powder is sprinkled on the food but are the tablets also to be taken with food
Thank you

John Cousins
  • Veterinary Surgeon

This product is normally taken with food. The tablets can be given whole or crushed, but some food is normally given at the same time or afterwards. The powder is much better given with some food.


31st Oct 2015
Maryann Rice
  • VioVet Customer Since: August 2015
  • From: North Lanarkshire, United Kingdom

If the dog stops taking this can it damage it thanks

  • Marketing Assistant

Hi Maryann,

If the vet has recommended you stop giving this to your dog then that's fine. Otherwise the dog would just not be getting any liver support.

Hope this helps,



12th Oct 2015
Ym Heo

What is the difference between small and medium breed?Is it only capacity of difference or there are other differences or ingredients?

John Cousins
  • Veterinary Surgeon

The difference is purely in the amount of ingredients per sachet, they are the same otherwise.

Right dosage for a heavy cat.

6th Oct 2015
Allan Feliciano

My cat weighs seven kilos and his ALT has been so high. We have been giving him two packs of samylin for months. Should we be giving him ONE or TWO?

John Cousins
  • Veterinary Surgeon

It is safe to give 2 sachets for such a large cat, but I would be tempted to give just one sachet daily from now on. I would also suggest that if your cat is overweight (it certainly sounds like it must be) then very gradual weight loss would be very helpful too. Fat builds up in the liver and is not a good thing.

Dog with liver problems

21st Mar 2015
Emma West

My 13 y o fox terrier, has been diagnosed with Liver problems. But have refused to allow vet, to do anymore investigations, as he is elderly. I have just started him on Denamarin, as you offer other products for liver problems,Samylin, milk thistle, can they be given together with Denamarin, which contains some of the same, ingredients ? or will it just be overdosing, and a waste of money ? Thanks

John Cousins
  • Veterinary Surgeon

There is a lot of overlap in the ingredients contained in most liver supplements. Samylin contains enough of them by itself to be effective so I would not add anything to it, that would be unlikely to make any difference.