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Zolvix Oral Solution for Sheep

Zolvix Oral Solution for Sheep
500ml Bottle

  • 500ml Bottle £135.99
  • 1 Litre Bottle £197.99
  • 2.5 Litre Bottle £444.99

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Zolvix Oral Solution for Sheep

Species: Sheep Therapeutic indication: Pharmaceuticals: Endoparasiticides: Anthelmintics for sheep Active ingredient: Monepantel Product:Zolvix® Oral Solution for Sheep Product index: Zolvix Oral Solution for Sheep Sheep - meat: 7 days


Zolvix is an orange clear oral solution containing 25 mg/ml monepantel.


Zolvix oral solution is a broad spectrum anthelmintic for the treatment and control of gastro-intestinal nematode infections and associated diseases in sheep including lambs, hoggets, breeding rams and ewes. Zolvix can be used in pregnant and lactating ewes. Spectrum of activity includes fourth stage larvae and adults of: Haemonchus contortus*, Teladorsagia circumcincta*, Teladorsagia trifurcata*, Teladorsagia davtiani*, Trichostrongylus axei*, Trichostrongylus columbriformis, Trichostrongylus vitrinus, Cooperia curticei, Cooperia oncophora, Nematodirus battus, Nematodirus filicollis, Nematodirus spathiger, Chabertia ovina, Oesophagostomum venulosum. * including inhibited larvae The veterinary medicinal product is effective against strains of these parasites resistant to (pro)benzimidazoles, levamisole, morantel, macrocyclic lactones and H. contortus strains resistant to salicylanilides.

Dosage and administration

Zolvix should be administered orally to sheep as a single treatment, however the administration may be repeated, depending on the epidemiological situation in different areas. To ensure complete swallowing of this low volume solution, Zolvix should be administered using an appropriate drench gun on the back of the tongue. Accuracy and proper functioning of the dosing device should be checked and the drenching equipment should be cleaned after use. If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed according to the heaviest animal within the group in order to avoid underdosage. The recommended dose rate is 2.5 mg per kg bodyweight of monepantel according to the following recommendations:

Body weight (kg) Dose (ml)
10-15 1.5
16-20 2
21-25 2.5
26-30 3
31-35 3.5
36-40 4
41-50 5
51-60 6
61-70 7
>70 1 ml for each additional 10 kg

Contra-indications, warnings, etc

Contra-indications: None. Special Warnings: Safety and efficacy have not been established in sheep weighing less than 10 kg or under 2 weeks of age. No adverse effects were observed after a 10-fold overdose. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy. - Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. - Underdosing, which may be due to underestimation of body weight, misadministration of the veterinary medicinal product, or lack of calibration of the dosing device. In order to help delay the development of resistance, users are advised to check the success of the treatment (e.g. clinical appearance, faecal egg counts). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Tests). Where the results of the tests strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Adverse reactions: None Operator warnings: Personal protective equipment consisting of gloves should be worn when handling the veterinary medicinal product. In case of accidental spillage onto skin or into eyes, wash immediately with water. Take off any contaminated clothes. In case of accidental ingestion seek medical advice immediately and show the package leaflet or the label to the physician. Do not eat, drink or smoke whilst handling the veterinary medicinal product. Wash hands and exposed skin after handling the veterinary medicinal product. Withdrawal period: Meat - 7 days. Not authorised for use in lactating animals producing milk for human consumption. Incompatibilities: In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.

Pharmaceutical precautions

Zolvix does not require any special storage conditions. Zolvix has a shelf life of 3 years in HDPE bottles. Use within 12 months of opening. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Legal category: POM-VPS

Packaging quantities

500ml, 1 litre and 2.5 litres in fluorinated high density polyethylene (HDPE) bottles with a polypropylene cap.

Further information

Zolvix should be used holistically with other classes of anthelmintic in order to help preserve efficacy of all worm drenches. Zolvix may be used to manage resistance and help preserve existing classes of anthelmintic. Zolvix is the first active ingredient from the 4-AD (orange) drench class and has a unique mode of action which differs from existing anthelmintics. Zolvix kills the economically important nematodes of sheep. Monepantel is an anthelmintic belonging to the amino-acetonitrile derivative (AAD) class of molecules. Monepantel acts on the nematode specific nicotinic acetylcholine receptor sub-unit Hco-MPTL-1. This is the first biological function to be described for the Hco-MPTL-1 receptor and therefore monepantel is effective against nematodes resistant to other anthelmintic classes. After oral administration monepantel is readily absorbed and oxidised to a sulfone metabolite. Peak blood concentrations are reached within a day. Afterwards blood concentrations decrease with a half life of about five days. Excretion is mainly via the faeces but also via the urine. Feeding or fasting before or shortly after treatment does not influence efficacy.

Marketing Authorisation Holder (if different from distributor)


Marketing Authorisation Number



GTIN description:Zolvix 500ml HDPE bottle GTIN:05037694091156 GTIN description:Zolvix 1L HDPE bottle GTIN:05037694053314 GTIN description:Zolvix 1L HDPE bottle promo GTIN:05037694053321 GTIN description:Zolvix 2.5L HDPE bottle GTIN:05037694053338 GTIN description:Zolvix 2.5L HDPE bottle promo GTIN:05037694053345

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All prices include VAT where applicable.

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.


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