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Vetivex Solutions for Injection or Infusion

Vetivex Solutions for Injection or Infusion
Isolec Hartmann's Solution » 250ml
No. 1 » Normal Saline » 100ml

  • Isolec Hartmann's Solution » 250ml £5.50
  • Isolec Hartmann's Solution » 500ml £7.99
  • Isolec Hartmann's Solution » 1 litre £7.99
  • Isolec Hartmann's Solution » 3 litre £18.49
  • Isolec Hartmann's Solution » 5 litre £17.50
  • No. 1 » Normal Saline » 100ml £4.69
  • No. 1 » Normal Saline » 500ml £5.99
  • No. 1 » Normal Saline » 1 litre £7.00
  • No. 1 » Normal Saline » 2 litre £18.49

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Description

A range of solutions designed to be given usually by intra-venous infusion.

Need help or advice? Contact us:

  • Landline: 01582 842096
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All prices include VAT where applicable.

Medication Datasheets

Isolec Hartmann's Solution » 500ml

Vetivex® (Hartmann's) 11 Solution for Infusion for Cattle, Horses, Dogs and Cats

Qualitative and quantitative composition

1 ml contains: Active substances:

Sodium lactate 3.20 mg

Sodium chloride 6.00 mg

Potassium chloride 0.40 mg

Calcium chloride 0.20 mg

(equivalent to Calcium chloride dihydrate 0.27 mg)

Sodium 131 mmol/litre

Potassium 5 mmol/litre

Calcium 2 mmol/litre

Bicarbonate (as lactate) 29 mmol/litre

Chloride 111 mmol/litre

Pharmaceutical form

Solution for infusion. Clear, colourless solution.

Clinical particulars

Target species

Cattle, horses, dogs and cats.

Indications for use

This veterinary medicinal product is administered by intravenous infusion for the treatment of dehydration and metabolic acidosis in cattle, horses, dogs and cats. It may be used to correct volume depletion (hypovolaemia) resulting from gastrointestinal disease or shock.

Contraindications

Do not use in animals with:

- hyperkalaemia

- hypercalcaemia

- hypernatraemia

- hyperlactataemia

- hyperhydration

- metabolic alkalosis

- oedema (hepatic, renal, or cardiac)

- Addison's disease

Special precautions for use in animals

Do not use unless the solution is clear, free from visible particles, and the container is undamaged.

A risk of thrombosis with intravenous infusion should be considered.

Maintain aseptic precautions.

This veterinary medicinal product should be warmed to approximately 37°C prior to the administration of large volumes, or if the administration rate is high, in order to avoid hypothermia.

This veterinary medicinal product does not contain an antimicrobial preservative. It is intended for single use only and any unused contents should be discarded.

Use of this solution requires monitoring of the clinical and physiological status of the animal especially in cases of:

- severe renal impairment

- cardiac impairment

- sodium retention with oedema

- treatments with corticosteroids and their derivatives.

This veterinary medicinal product should be used with caution in animals with cardiac or renal impairment as sodium overload may occur. It should be noted that sodium excretion may be impaired post-surgery/trauma.

Monitor serum potassium and serum calcium in treated animals, particularly potassium levels in cases at risk of hyperkalaemia, such as during chronic renal failure.

In animals with hepatic impairment, the product may not produce its alkalising action since lactate metabolism may be altered.

Adverse reactions

Skin reactions (urticarial, eczema, skin lesions) and allergic oedema are very rarely observed.

The frequency of adverse reactions is defined using the following convention:

- very common (more than 1 in 10 animals displaying adverse reaction(s))

- common (more than 1 but less than 10 animals in 100 animals treated)

- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)

- rare (more than 1 but less than 10 animals in 10,000 animals treated)

- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Use during pregnancy and lactation

The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only according to the benefit/risk assessment by the responsible veterinarian.

Interactions

This veterinary medicinal product is incompatible with methylprednisolone, and sodium lactate or sodium bicarbonate intravenous infusions.

Interactions linked to calcium.

In case of concomitant blood transfusion, the product should not be administered with the blood in the same infusion set due to the risk of clotting. This veterinary medicinal product contains calcium. Do not add drugs to this solution that may bind (chelate) to calcium.

Amounts to be administered and administration route

Intravenous use.

The infusion should ideally be warmed to approximately 37°C prior to administration.

The volume and rate of infusion will depend upon the clinical condition, existing deficits of the animal, maintenance needs and continuing losses.

Generally aim to correct hypovolaemia by 50% initially (ideally over 6 hours but faster if necessary) and reassess by clinical examination.

Deficits are generally in the range of 50 ml/kg (mild) to 150 ml/kg (severe). An infusion rate of 15 ml/kg/hour is recommended in the absence of shock (range 5-75 ml/kg/hour).

In shock, high initial infusion rates, up to 90 ml/kg/hour, are needed. High infusion rates should not be continued for longer than 1 hour unless renal function and urine output are restored. The maximum infusion rate should be decreased in the presence of cardiac, renal and pulmonary disease.

Overdose

In the presence of volume overload signs (eg restlessness, moist lung sounds, tachycardia, tachypnoea, nasal discharge, coughing, vomiting and diarrhoea), treatment should involve administering diuretics and stopping the infusion. An excessive infusion of product may cause metabolic alkalosis due to the presence of lactate ions.

Withdrawal periods

Meat and offal: zero days.

Milk: zero hours.

Pharmacological particulars

Pharmacotherapeutic group: Electrolytes

ATCvet code: QB05BB01

Pharmacodynamic properties

Isotonic crystalloid solutions are for vascular filling and electrolyte replacement. They have an ionic composition very close to the extracellular fluid.

Sodium is the major cation of extracellular fluid. It is responsible for maintaining the volume of liquid and extracellular osmolarity.

Potassium is mainly an intracellular cation.

99% of calcium is present in the skeleton.

Chloride is essentially an extracellular anion.

Lactate produces bicarbonate salts (hence its alkalising effect).

Pharmacokinetic properties

The solution diffuses into the extracellular space whose volume is increased accordingly.

The lactate ion is rapidly metabolised by the liver where it is converted to pyruvate used in the Krebs cycle with production of bicarbonates.

Pharmaceutical particulars

Incompatibilities

This veterinary medicinal product is incompatible with methylprednisolone, and sodium lactate or sodium bicarbonate intravenous infusions.

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

The veterinary medicinal product should be used immediately and not stored after opening.

Special precautions for storage

Do not store above 25°C.

Do not freeze.

Immediate packaging

Polyvinylchloride infusion bags overwrapped with polypropylene.

All pack sizes have two ports. In place of the additive port on the 5000 ml combi pack is a combi port. This enables two such bags to be connected in sequence and volumes greater than 5000 ml to be administered during one infusion.

Pack sizes: Individual fluid bags of 250 ml, 500 ml, 1000 ml, 3000 ml, 5000 ml and 5000 ml combi, each supplied with a package leaflet, or boxes containing 20 x 250 ml, 20 x 500 ml, 10 x 1000 ml, 4 x 3000 ml, 2 x 5000 ml, 2 x 5000 ml combi.

Not all pack sizes may be marketed.

Disposal

Any unused veterinary medicinal product or waste materials derived from such medicinal products should be disposed of in accordance with local requirements.

Marketing Authorisation Holder (if different from distributor)

Dechra Limited, Snaygill Industrial Estate, Keighley Road, Skipton, North Yorkshire, BD23 2RW, United Kingdom.

Marketing Authorisation Number

Vm 10434/4080

Date of the first authorisation or date of renewal

20 June 2013

Date of revision of the text

July 2018

Any other information

For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.

Legal category

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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