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Ventipulmin for Horses

Ventipulmin for Horses
Granules » 500g Tub
Injection Solution » 50ml Multidose Vial
Syrup » 355ml Bottle

  • Granules » 500g Tub £52.49
  • Injection Solution » 50ml Multidose Vial £62.99
  • Syrup » 355ml Bottle £52.99

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£52.49 to £62.99

Description

Ventipulmin is a drug used to open the respiratory passages of horses and to help clear them of mucus. This can be beneficial in some allergic respiratory diseases, often associated with a cough, due to mould spores in hay and straw (chronic obstructive pulmonary disease or COPD). Ventipulmin is also useful in cases where infection of the respiratory tract is involved, such as equine influenza. Where bacterial infection is present, antibiotics can be used as well. Ventipulmin is available as Ventipulmin Granules or Ventipulmin Syrup to add to food. There is also a Ventipulmin Injection available.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

Granules » 500g Tub

Ventipulmin Granules 16 micrograms/gram

Presentation

White, finely grained free flowing granules. Each gram of granules contains 16 micrograms of clenbuterol hydrochloride.

Uses

Treatment of respiratory disease in horses where airway obstruction due to bronchospasm and/or accumulation of mucus is a contributing factor, and improved mucociliary clearance is desirable. To be used alone or as adjuvant therapy.

In particular:

Dosage and administration

For oral administration.

Twice daily administration of 0.8 micrograms clenbuterol per kg bodyweight, for as long as necessary. This is equivalent to twice daily administration of 5g granules per 100kg bodyweight. The granules should be added to the feed.

Add to feed immediately before administration. Discard any remaining medicated feed. A measuring scoop is provided with the 500g pack. When full, the scoop contains 10g. A second line on the scoop indicates a half measure (5g).

Contra-indications, warnings, etc

Do not use in horses with known cardiac disease.

Special precautions for use in animals

Do not use in animals with known hypersensitivity to the active substance.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

This product contains clenbuterol, a beta-agonist.

Take care to avoid skin contact. In case of skin contact wash affected area thoroughly. If irritation occurs/persists seek medical advice. Take care to avoid accidental eye contact. In the case of accidental eye contact, flush thoroughly with clean water and seek medical advice. When using do not eat, drink or smoke. Wash hands thoroughly after using the product. Avoid inhaling dust.

Clenbuterol may cause side effects such as sweating (mainly neck region), muscle tremor, tachycardia, slight hypotension or restlessness. These are typical for β-agonists and occur rarely.

Ventipulmin antagonises the effects of prostaglandin F2α and oxytocin.

Ventipulmin is antagonised by β-adrenergic blocking agents.

If used during pregnancy, treatment must be discontinued at the expected time of delivery since uterine contractions may be abolished under its influence.

Dosages of clenbuterol hydrochloride up to 4 times the therapeutic dose (administered orally) for a period of 90 days caused transient side effects typical for beta2-adrenoceptor agonists (sweating, tachycardia, muscle tremor), which required no treatment. In case of accidental overdose, a β-blocker (such as propranolol) may be used as antidote.

Withdrawal period

Meat and offal: 28 days

Do not use in animals producing milk for human consumption.

Pharmaceutical precautions

Shelf life of the medicinal product as packaged for sale : 3 years.

Do not store above 30°C. Protect from light. Discard unused material. Add to feed immediately before administration. Discard remaining medicated feed.

Keep out of the reach and sight of children. For animal treatment only.

To be supplied only on veterinary prescription.

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

The product is packed in a polyethylene container with a push-fit polyethylene cap. The container is filled with 500 g granules. A polystyrene measuring spoon, graduated at 5g and 10g is also supplied.

Further information

The product contains the active ingredient clenbuterol hydrochloride which is a sympathomimetic amine with a high degree of selectivity for the B2-receptor sites in the body, thus providing intense bronchodilating properties with minimum effect on the cardiovascular system. It has been shown to stimulate mucociliary clearance in horses.

The effects on pulmonary function and clinical response have been assessed in clinical trials with horses suffering from a variety of respiratory conditions.

A marked decrease in intrathoracic pressure, a decrease in respiratory rate, an initial decrease followed by an increase in arterial oxygen partial pressure and clinical improvements were observed.

In addition, a significant reduction in resistance to airflow and a clinical improvement in the animals respiratory pattern were seen.

The active substance is well absorbed following oral administration. Oral and parenteral dose rates are identical at 0.08 micrograms per kg bodyweight.

Marketing Authorisation Number

Vm 00015/4040

Syrup » 355ml Bottle

Ventipulmin Syrup 25 micrograms/ml

Presentation

Clear colourless syrup. Each ml contains 25 micrograms clenbuterol hydrochloride as active substance plus 1.8 mg methyl parahydroxybenzoate and 0.2 mg propyl parahydroxybenzoate as excipients.

Uses

Treatment of respiratory disease in horses where it is considered that airway obstruction due to bronchospasm and/or accumulation of mucus is a contributing factor, and improved mucociliary clearance is desirable. To be used alone or as adjuvant therapy..

In particular:

In cases complicated by bacterial infection, the administration of antimicrobial agents is recommended.

Dosage and administration

For oral use. Administer 4 ml Ventipulmin Syrup per 125 kg bodyweight twice daily.

This is equivalent to twice daily administration of 0.8 micrograms clenbuterol hydrochloride per kg bodyweight. The syrup should be added to the feed. (One depression of the pump delivers 4 ml syrup). Treatment should continue for as long as necessary.

Contra-indications, warnings, etc

Do not use in cases of known hypersensitivity to the active ingredient. Do not use in horses with known cardiac disease.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

This product contains clenbuterol, a beta-agonist.

Take care to avoid skin contact. In case of skin contact wash affected area thoroughly. If irritation occurs/persists seek medical advice. Take care to avoid accidental eye contact. In the case of accidental eye contact, flush thoroughly with clean water and seek medical advice. When using do not eat, drink or smoke. Wash hands thoroughly after using the product.

Clenbuterol may cause side effects such as sweating (mainly neck region), muscle tremor, tachycardia, slight hypotension or restlessness. These are typical for β-agonists and occur rarely.

If used during pregnancy, treatment must be discontinued at the expected time of delivery since uterine contractions may be abolished under its influence.

Ventipulmin antagonises the effects of prostaglandin F2α and oxytocin. Ventipulmin is antagonised by β-adrenergic blocking agents.

Dosages of clenbuterol hydrochloride up to 4 times the therapeutic dose (administered orally) for a period of 90 days caused transient side effects typical for beta2-adrenoceptor agonists (sweating, tachycardia, muscle tremor), which required no treatment. In case of accidental overdose, a β-blocker (such as propranolol) may be used as antidote.

Withdrawal period

Meat and offal: 28 days.

Do not use in animals producing milk for human consumption.

Pharmaceutical precautions

Shelf life of the medicinal product as packaged for sale : 2 years.

Shelf life after first opening the immediate packaging : 30 days.

Do not store above 25°C. Protect from light.

Keep out of the reach and sight of children. For animal treatment only.

To be supplied only on veterinary prescription. Keep the bottle in outer carton.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

355ml screw top polyethylene bottle with a 4ml pump dispenser.

Further information

Pharmacotherapeutic group: Adrenergics for systemic use (selective beta2-adrenoreceptor agonists)

ATC Vet code : QR03CC13: Drugs for obstructive airway disease.

Pharmacodynamic properties

Ventipulmin contains clenbuterol hydrochloride, which is a sympathomimetic amine which preferentially binds to β2 adrenoreceptors on cell membranes of the bronchi. This subsequently activates the enzyme adenylate cyclase in smooth muscle cells, thus providing intense bronchodilating properties and decreasing airway resistance with minimum effect on the cardiovascular system. Ventipulmin has been shown to inhibit histamine release from mast cells in the lungs, and enhance mucociliary clearance in horses.

Pharmacokinetic particulars

After oral administration in horses, clenbuterol is readily absorbed and maximum plasma concentrations reached within 2 hours of dosing. Steady state level in plasma is reached after 3-5 days treatment and range from 1.0 – 2.2 ng/ml.

The substance is rapidly distributed in tissues and metabolised primarily by the liver. Clenbuterol is the main excretory product and approximately 45% of the dose is eliminated unchanged in the urine. The kidneys excrete 70 – 91% of the total dose, and the remainder is eliminated in the faeces (6 – 15%).

Marketing Authorisation Number

Vm 00015/4032.

Injection Solution » 50ml Multidose Vial

Ventipulmin Solution for Injection 30 micrograms/ml

Presentation

Clear colourless solution for injection. Each ml contains 30 micrograms clenbuterol hydrochloride as active substance and 10 mg benzyl alcohol as preservative.

Uses

Treatment of respiratory disease in horses where it is considered that airway obstruction due to bronchospasm and/or accumulation of mucus is a contributing factor, and improved muco-ciliary clearance is desirable. To be used alone or as adjuvant therapy.

In particular:

Dosage and administration

Administer by slow intravenous injection at a dose of 2.7ml per 100kg bodyweight twice daily for as long as necessary. This is equivalent to twice daily administration of 0.8 micrograms clenbuterol hydrochloride per kg bodyweight.

Contra-indications, warnings, etc

Do not use in horses with known cardiac disease.

Special precautions for use in animals

Do not use in cases of known hypersensitivity to clenbuterol

Special precautions to be taken by the person administering the veterinary medicinal product to animals

This product contains clenbuterol, a β-agonist. Take care to avoid skin contact. In case of skin contact wash affected area thoroughly. If irritation occurs/persists seek medical advice. Take care to avoid accidental eye contact. In the case of accidental eye contact, flush thoroughly with clean water and seek medical advice. When using do not eat, drink or smoke. Wash hands thoroughly after using the product.

Accidental self-injection may produce tachycardia and tremor. These effects may be reversed by the use of a non-selective beta-blocker. If accidental self-injection occurs seek medical advice immediately, avoiding driving if possible.

In clinical use, it has been noted that following intravenous administration to horses, cases of transient mild muscle tremor and sweating were observed. It is suggested that a ‘bolus’ effect may have occurred in these cases and caused transient peripheral vasodilation. This vasodilation is a feature exhibited by all beta-adrenergic drugs to a greater or lesser degree. These effects may be minimised by administering the product slowly.

If used during pregnancy, treatment must be discontinued at the expected time of delivery since uterine contractions may be abolished under its influence.

This product antagonises the effects of prostaglandin F2-alpha and oxytocin. This product is antagonised by beta-adrenergic blocking agents.

In case of accidental overdose, a β-blocker such as propanolol may be used.

Withdrawal period

Meat and offal: 28 days.

Do not use in animals producing milk for human consumption.

Pharmaceutical precautions

Shelf life of the medicinal product as packaged for sale : 3 years.

Shelf life after first opening the immediate packaging : 28 days.

Do not store above 25°C. Protect from light. Following withdrawal of the first dose use the product within 28 days. Discard unused material. Avoid the introduction of contamination during use. Should any growth or discolouration occur the product should be discarded.

To be supplied only on veterinary prescription.

Keep out of the reach and sight of children. For animal treatment only.

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

50ml amber glass injection vial (Ph Eur. Type II), with pink bromobutyl rubber stopper and aluminium crimp cap.

Further information

The product contains the active ingredient clenbuterol hydrochloride, which is a sympathomimetic amine with a high degree of selectivity for the B2-receptor sites in the body, thus providing intense bronchodilating properties with minimum effect on the cardiovascular system. It has been shown to stimulate muco-ciliary clearance in horses.

The effects on pulmonary function and clinical response have been assessed in clinical trials with horses suffering from a variety of respiratory conditions.

A marked decrease in intrathoracic pressure, a decrease in respiratory rate, an initial decrease followed by an increase in arterial oxygen partial pressure and clinical improvements were observed. In addition, a significant reduction in resistance to airflow and a clinical improvement in the animals respiratory pattern were seen.

Marketing Authorisation Number

Vm 00015/4039.

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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