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Selgian is used to treat behavioural disorders in dogs which are associated with emotional upset, such as depression or anxiety. Ideally it is used alongside behaviour therapy when it is able to improve signs such as overactivity, phobias and anti-social behaviour. Selgian can also help dogs which have difficulty coping with periodic separation from their owners. Problems such as inappropriate urination or destructiveness when left alone can be improved. Selgian Tablets are given once daily for at least 2 months. The average treatment period is about 4 or 5 months, but can be longer. When required, it is acceptable to stop the medication suddenly, without a gradual withdrawal.
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Cross-scored film-coated tablets, divisible into quarters by means of a groove to facilitate accurate dosage, for oral administration to dogs. Each tablet contains 4, 10 or 20 mg (-) selegiline hydrochloride.
Selegiline hydrochloride is an inhibitor of monoamine oxidase (IMAO type B) at the therapeutic dose in the dog; thus it modifies the concentration of monoaminergic neurotransmitters.
It is indicated for use as follows:
Oral route: 0.5 mg/kg/day of (ā) selegiline hydrochloride in a single administration.
For dogs weighing less than 8 kg, the use of SelgianĀ® 4 mg is advisable. For dogs weighing more than 17 kg, the use of SelgianĀ® 10 mg or SelgianĀ® 20 mg is advisable. For dogs weighing less than 26 kg, the use of SelgianĀ® 4 mg or 10 mg is advisable.The treatment should be continued until the clinical condition is stable.
The minimum treatment period recommended is 2 months, based on the clinical trials results:
The treatment period was 2-3 months for 20% of the dogs.
The treatment period was 4-5 months for 50% of the dogs.
The treatment period was 6-7 months for 20% of the dogs.
The treatment period was >7 months for 10% of the dogs.
The treatment can be stopped suddenly without gradual dose reductions.
Contra -indications
Owing to its IMAO properties, (-) selegiline hydrochloride may act on prolactin secretion. In the absence of specific studies, it is recommended that SelgianĀ® should not be administered to pregnant and lactating bitches.
SelgianĀ® should not be administered from the day before until the day after anaesthesia or tranquillisation performed with an alpha-2 agonist.
Do not administer with other alpha-2 agonists.
SelgianĀ® should not be administered concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by SelgianĀ®.
Adverse reactions
Trials have shown that some dominant dogs, with behavioural disorders but no signs of aggression, may become aggressive after treatment. Those previously showing aggression may have this enhanced. Appropriate training is essential in such cases.
Use during pregnancy, lactation or lay
It is recommended to stop the treatment during pregnancy and lactation.
Special precautions for use in animals
Emotional disorders can mask hierarchical conflicts. In dominant dogs suffering from an emotional disorder, the alleviation of the disorder can sometimes reveal a latent aggressiveness. In such cases, behavioural therapy must be instituted.
Special precautions to be taken by the person administering the medicinal product to animals
In the event of accidental ingestion, seek medical advice and show the doctor the package leaflet. Wash hands after use.
If no clinical improvement is observed after 2 months, continuing the treatment is unlikely to provide any further benefit. It is advisable to weigh animals before dosing to ensure the correct mg/kg dosage is administered.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
For animal treatment only. Keep out of reach and sight of children.
Store below 25°C. The tablets are divisible into quarters. Tablet portions can be kept for 4 days in the blister pack.
Box containing 3 blisters of 10 tablets.
Box containing 10 blisters of 10 tablets (for Selgian 10 mg only)
Vm 14966/4000
Vm 14966/4001
Vm 14966/4004
Cross-scored film-coated tablets, divisible into quarters by means of a groove to facilitate accurate dosage, for oral administration to dogs. Each tablet contains 4, 10 or 20 mg (-) selegiline hydrochloride.
Selegiline hydrochloride is an inhibitor of monoamine oxidase (IMAO type B) at the therapeutic dose in the dog; thus it modifies the concentration of monoaminergic neurotransmitters.
It is indicated for use as follows:
Oral route: 0.5 mg/kg/day of (ā) selegiline hydrochloride in a single administration.
For dogs weighing less than 8 kg, the use of SelgianĀ® 4 mg is advisable. For dogs weighing more than 17 kg, the use of SelgianĀ® 10 mg or SelgianĀ® 20 mg is advisable. For dogs weighing less than 26 kg, the use of SelgianĀ® 4 mg or 10 mg is advisable.The treatment should be continued until the clinical condition is stable.
The minimum treatment period recommended is 2 months, based on the clinical trials results:
The treatment period was 2-3 months for 20% of the dogs.
The treatment period was 4-5 months for 50% of the dogs.
The treatment period was 6-7 months for 20% of the dogs.
The treatment period was >7 months for 10% of the dogs.
The treatment can be stopped suddenly without gradual dose reductions.
Contra -indications
Owing to its IMAO properties, (-) selegiline hydrochloride may act on prolactin secretion. In the absence of specific studies, it is recommended that SelgianĀ® should not be administered to pregnant and lactating bitches.
SelgianĀ® should not be administered from the day before until the day after anaesthesia or tranquillisation performed with an alpha-2 agonist.
Do not administer with other alpha-2 agonists.
SelgianĀ® should not be administered concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by SelgianĀ®.
Adverse reactions
Trials have shown that some dominant dogs, with behavioural disorders but no signs of aggression, may become aggressive after treatment. Those previously showing aggression may have this enhanced. Appropriate training is essential in such cases.
Use during pregnancy, lactation or lay
It is recommended to stop the treatment during pregnancy and lactation.
Special precautions for use in animals
Emotional disorders can mask hierarchical conflicts. In dominant dogs suffering from an emotional disorder, the alleviation of the disorder can sometimes reveal a latent aggressiveness. In such cases, behavioural therapy must be instituted.
Special precautions to be taken by the person administering the medicinal product to animals
In the event of accidental ingestion, seek medical advice and show the doctor the package leaflet. Wash hands after use.
If no clinical improvement is observed after 2 months, continuing the treatment is unlikely to provide any further benefit. It is advisable to weigh animals before dosing to ensure the correct mg/kg dosage is administered.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
For animal treatment only. Keep out of reach and sight of children.
Store below 25°C. The tablets are divisible into quarters. Tablet portions can be kept for 4 days in the blister pack.
Box containing 3 blisters of 10 tablets.
Box containing 10 blisters of 10 tablets (for Selgian 10 mg only)
Vm 14966/4000
Vm 14966/4001
Vm 14966/4004
Cross-scored film-coated tablets, divisible into quarters by means of a groove to facilitate accurate dosage, for oral administration to dogs. Each tablet contains 4, 10 or 20 mg (-) selegiline hydrochloride.
Selegiline hydrochloride is an inhibitor of monoamine oxidase (IMAO type B) at the therapeutic dose in the dog; thus it modifies the concentration of monoaminergic neurotransmitters.
It is indicated for use as follows:
Oral route: 0.5 mg/kg/day of (ā) selegiline hydrochloride in a single administration.
For dogs weighing less than 8 kg, the use of SelgianĀ® 4 mg is advisable. For dogs weighing more than 17 kg, the use of SelgianĀ® 10 mg or SelgianĀ® 20 mg is advisable. For dogs weighing less than 26 kg, the use of SelgianĀ® 4 mg or 10 mg is advisable.The treatment should be continued until the clinical condition is stable.
The minimum treatment period recommended is 2 months, based on the clinical trials results:
The treatment period was 2-3 months for 20% of the dogs.
The treatment period was 4-5 months for 50% of the dogs.
The treatment period was 6-7 months for 20% of the dogs.
The treatment period was >7 months for 10% of the dogs.
The treatment can be stopped suddenly without gradual dose reductions.
Contra -indications
Owing to its IMAO properties, (-) selegiline hydrochloride may act on prolactin secretion. In the absence of specific studies, it is recommended that SelgianĀ® should not be administered to pregnant and lactating bitches.
SelgianĀ® should not be administered from the day before until the day after anaesthesia or tranquillisation performed with an alpha-2 agonist.
Do not administer with other alpha-2 agonists.
SelgianĀ® should not be administered concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by SelgianĀ®.
Adverse reactions
Trials have shown that some dominant dogs, with behavioural disorders but no signs of aggression, may become aggressive after treatment. Those previously showing aggression may have this enhanced. Appropriate training is essential in such cases.
Use during pregnancy, lactation or lay
It is recommended to stop the treatment during pregnancy and lactation.
Special precautions for use in animals
Emotional disorders can mask hierarchical conflicts. In dominant dogs suffering from an emotional disorder, the alleviation of the disorder can sometimes reveal a latent aggressiveness. In such cases, behavioural therapy must be instituted.
Special precautions to be taken by the person administering the medicinal product to animals
In the event of accidental ingestion, seek medical advice and show the doctor the package leaflet. Wash hands after use.
If no clinical improvement is observed after 2 months, continuing the treatment is unlikely to provide any further benefit. It is advisable to weigh animals before dosing to ensure the correct mg/kg dosage is administered.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
For animal treatment only. Keep out of reach and sight of children.
Store below 25°C. The tablets are divisible into quarters. Tablet portions can be kept for 4 days in the blister pack.
Box containing 3 blisters of 10 tablets.
Box containing 10 blisters of 10 tablets (for Selgian 10 mg only)
Vm 14966/4000
Vm 14966/4001
Vm 14966/4004
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Value For Money | |
Absence Of Side Effects |
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This took about 12 days to work. My dog was a lot calmer and stopped barking at night. She was 17 and her back legs were going. If she fell she would bark to be helped up. It seemed to help with her incontinence at first also , maybe because she was more aware she was going to need to wee. She interacted with us again . I would recommend this for an old dog.
Customer recommends this product
My vet prescribed Selgian for Jay as he had a number of behavioural problems which was put down to doggy dementia ( he is 13 and a springer spaniel). It has eased some of his anxiety issues, although not all of them and is much cheaper to buy from viovet ( with an online prescription) than from my vets
Customer recommends this product
1 person found this review helpful
Below are some recent questions we've received regarding Selgian Tablets for Dogs, including answers from our team.
R Smith
My elderly dog has been on Selgian now for over 2 weeks for ccd. Can the side effects make her stumble more and lose control of her back legs to a certain extent? Iām becoming worried about the side effects as Iām unsure whether the tablets are going to be any help and was thinking maybe it is best to stop them.
This is not a side effect usually seen with Selgian. That said there is always potential for a dog to react in any way to a given drug. The only way to know would be to stop the Selgian and see if she improves. However you should speak to your own vet first before stopping treatment and it would be a good idea for them to have a look at your dog to rule out any other underlying causes for her symptoms.
Joe
I have a 16 year old Jack Russell terrier who has begun to show signs of Canine Cognitive Dysfunction, he is quiet in the day and sleeps without issue, but at night he barks endlessly until I come down to him (he can't walk up the stairs so he sleeps downstairs), he also paces around his sleeping space constantly, getting in his basket, instantly getting back out, pacing, then repeat. We have been recommended Selgian, and as our dog is approximately 12KG in weight, it was advised that he takes one 10mg tablet per day, but I have read on several websites that the recommended dosage is 0.5mg per KG, which would put the dosage for his weight at 6mg per day, not 10mg. Would you recommend that he takes a 10mg tablet per day, or half a tablet as per the dosage recommendations online, as the tablets are very expensive and I would prefer 30 tablets to last 2 months not just 1. It may have been recommend that he takes the full 10mg per day because his behaviour at night (or when left alone) is quite severe and half a tablet may be ineffective.
Many thanks.
You are right that the recommended dose is half a tablet daily for your dogs weight. However as you say his behaviour is quite severe and the bigger dose may be more helpful. You certainly won't overdose. You could try giving half a tablet daily and see what response you get on this dose. If it is not effective enough you can go up to 1 tablet daily.
Nicola Othen
What side effects can there be from selgian 10mg tablets for dogs?
Studies have shown that Selgian caused transient minor gastrointestinal irritation, e.g. salivation/ vomiting in 15/15000 administrations. It is also not recommended for use in pregnant or lactating bitches as it may interact with Prolactin and milk production.
Julie Howes
my dog is already on akitivalt. is it safe to also give him selgian with these.
Yes it is safe to give Selgian with Aktivait. They have very different ingredients and do not interact adversely at all.
Claire Cunningham
my american akita weighs 50kilos. he is 18mths old and fit.how much dosage will he need to help him chill out around people. thanks
The correct dose for your dog would be one and a quarter tablets daily. Ideally you should follow advice from a dog behaviour therapist at the same time, so as to get the maximum benefit from the tablets. He should become more receptive to being "trained" to improve, rather than hoping the tablets will do it all by themselves. (They might do, as long as you and the people he meets are able to respond appropriately to him. He needs to pick up the right signals from all of you to get the best benefit.)