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Protexin Denamarin Liver Supplement for Dogs & Cats

  • 90mg Tablets (Cat/Small Dog) » Pack of 30 £25.49
  • 225mg Tablets (Med Dog) » Pack of 30 £44.29
  • 425mg Tablets (Large Dog) » Pack of 30 £64.49

Selection of 3 products from

£25.49 to £64.49

Protexin Denamarin Tablets provide effective liver support for dogs and cats. Protexin Denamarin contains a stabilised form of the naturally occurring and biologically active S,S-SAMe isomer and Silybin which has been complexed with phosphatidylcholine. This is known to have a greater bio-availability than silymarin alone, so more of the product is taken in and used by the body.

Feeding Guidelines


Tablets should be given on an empty stomach at least one hour before a meal for optimum absorption (an overnight fast is preferred). The number of tablets administered may gradually be reduced, or increased, at any time at the recommendation of your veterinary surgeon.

Weight Cats and Small Dogs Medium Dogs Large Dogs
<5kg 1 tablet
5-15kg 1 tablet
15-30kg 1 tablet
30-55kg 2 tablets
>55kg 3 tablets

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Reviews of Protexin Denamarin Liver Supplement for Dogs & Cats

Read our customers' reviews of Protexin Denamarin Liver Supplement for Dogs & Cats

Questions & Answers for Protexin Denamarin Liver Supplement for Dogs & Cats

Below are some recent questions we've received regarding Protexin Denamarin Liver Supplement for Dogs & Cats, including answers from our team.

Ask Your Own Question

Giving Denamarin tablet

14th Mar 2018

I find it very difficult to get my dog to take the tablet. Sometimes it takes two or three attempts, by which time the tablet is losing its coating. Will this make any difference to the tablet's effectiveness? We have sometimes given it with a small amount of food, is this a problem?

  • Veterinary Advisor

The enteric coating of Denamarin protects the SAMe from degradation in the stomach so that the maximum amount can be absorbed in the small intestine. If the coating is lost then it is likely to be less effective. It is better as you say to give with a very small amount of food then give a main meal one hour later.

Protexin Denamarin

16th Feb 2017
Amanda Lloyd

Is Protein Denamarin a better option then Hepatosyl plus for liver problems?

  • Veterinary Advisor

Both products contain very similar ingredients. However it is thought that Denamarin is more bio-available so more of the product is absorbed and used by the body. Although, to my knowledge there have not been any studies which compare the two so it is difficult to say with certainty that Denamarin is better.

Denamarin with food

19th Sep 2015
Dan Jackson
  • VioVet Customer Since: March 2015
  • From: Sir Benfro, United Kingdom

Hello, as per the guidelines we give our Jack Russell the Denmarin 1 hour before eating, always in the morning. shortly we will be leaving her at a kennel for 8 days, will administering it with food be an issue for this short period. Some neighbours of ours always give it with food? Many thanks. Dan

  • Non-Executive Director

Giving it with food is often what people have to do, though it is less good than doing it as recommended. It will reduce the effectiveness of that particular dose, because the active ingredient will not be absorbed fully from the gut and will "come out the other end" without ever getting to the liver. However some will be absorbed and for a short period of a few days it is unlikely to make a noticeable difference. Ideally ask the kennels to give the medication with a minimal amount of food, then give a meal later. If they cannot then it should not be a disaster.


23rd Apr 2014

Is a prescription required for Denamarin?

  • Web Developer

No, Protexin Denamarin can be bought without the need for a prescription.