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Selgian is used to treat behavioural disorders in dogs which are associated with emotional upset, such as depression or anxiety. Ideally it is used alongside behaviour therapy when it is able to improve signs such as overactivity, phobias and anti-social behaviour. Selgian can also help dogs which have difficulty coping with periodic separation from their owners. Problems such as inappropriate urination or destructiveness when left alone can be improved. Selgian Tablets are given once daily for at least 2 months. The average treatment period is about 4 or 5 months, but can be longer. When required, it is acceptable to stop the medication suddenly, without a gradual withdrawal.
Cross-scored film-coated tablets, divisible into quarters by means of a groove to facilitate accurate dosage, for oral administration to dogs. Each tablet contains 4, 10 or 20 mg (-) selegiline hydrochloride.
Selegiline hydrochloride is an inhibitor of monoamine oxidase (IMAO type B) at the therapeutic dose in the dog; thus it modifies the concentration of monoaminergic neurotransmitters.
It is indicated for use as follows:
1.Treatment of behavioural disorders of purely emotional origin : depression, anxiety.
2.In association with behaviour therapy, treatment of signs of emotional origin observed in behavioural conditions such as overactivity, separation problems, generalised phobia and unsocial behaviour.
Emotional disorders are characterised by a modification of feeding, drinking, auto-stimulatory behaviour, sleep, exploratory behaviour, aggression related to fear and/or irritation, social behaviour and somatic disorders (tachycardia, emotional micturition).
For oral administration to dogs. The dose rate is 0.5 mg/kg/day (-) selegiline hydrochloride in a single administration.
Dog weight in kg
Number of tablets
For dogs weighing less than 8 kg, the use of Selgian® 4 mg is advisable. For dogs weighing more than 17 kg, the use of Selgian® 10 mg or Selgian® 20 mg is advisable. For dogs weighing less than 26 kg, the use of Selgian® 4 mg or 10 mg is advisable.
The treatment should be continued until the clinical condition is stable.
The minimum treatment period recommended is 2 months, based on the clinical trials results:
The treatment period was 2-3 months for 20% of the dogs.
The treatment period was 4-5 months for 50% of the dogs.
The treatment period was 6-7 months for 20% of the dogs.
The treatment period was >7 months for 10% of the dogs.
The treatment can be stopped suddenly without gradual dose reductions.
Owing to its IMAO properties, (-) selegiline hydrochloride may act on prolactin secretion. In the absence of specific studies, it is recommended that Selgian® should not be administered to pregnant and lactating bitches.
Selgian® should not be administered from the day before until the day after anaesthesia or tranquillisation performed with an alpha-2 agonist.
Do not administer with other alpha-2 agonists.
Selgian® should not be administered concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by Selgian®.
Emotional disorders can mask hierarchical conflicts. In dominant dogs suffering from an emotional disorder, the alleviation of the disorder can sometimes reveal a latent aggressiveness. In such cases, behavioural therapy must be instituted.
It is recommended to stop the treatment during pregnancy and lactation.
If no clinical improvement is observed after 2 months, continuing the treatment is unlikely to provide any further benefit. It is advisable to weigh animals before dosing to ensure the correct mg/kg dosage is administered.
Special precautions to be taken by the person administering the medicinal product to animals
In the event of accidental ingestion, seek medical advice and show the doctor the package leaflet. Wash hands after use.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
For animal treatment only. Keep out of reach and sight of children.
Store below 25°C. The tablets are divisible into quarters. Tablet portions can be kept for 4 days in the blister pack.
Box containing 3 blisters of 10 tablets.
Box containing 10 blisters of 10 tablets (for Selgian 10 mg only)
All prices include VAT where applicable.
Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.
For UK delivery, we charge the following:
Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.
For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.
We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.
Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.
Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.
Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.
To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.
*For full details on returns, see our terms and conditions page.
Below are some recent questions we've received regarding Selgian Tablets for Dogs, including answers from our team.
My elderly dog has been on Selgian now for over 2 weeks for ccd. Can the side effects make her stumble more and lose control of her back legs to a certain extent? I’m becoming worried about the side effects as I’m unsure whether the tablets are going to be any help and was thinking maybe it is best to stop them.
This is not a side effect usually seen with Selgian. That said there is always potential for a dog to react in any way to a given drug. The only way to know would be to stop the Selgian and see if she improves. However you should speak to your own vet first before stopping treatment and it would be a good idea for them to have a look at your dog to rule out any other underlying causes for her symptoms.
I have a 16 year old Jack Russell terrier who has begun to show signs of Canine Cognitive Dysfunction, he is quiet in the day and sleeps without issue, but at night he barks endlessly until I come down to him (he can't walk up the stairs so he sleeps downstairs), he also paces around his sleeping space constantly, getting in his basket, instantly getting back out, pacing, then repeat. We have been recommended Selgian, and as our dog is approximately 12KG in weight, it was advised that he takes one 10mg tablet per day, but I have read on several websites that the recommended dosage is 0.5mg per KG, which would put the dosage for his weight at 6mg per day, not 10mg. Would you recommend that he takes a 10mg tablet per day, or half a tablet as per the dosage recommendations online, as the tablets are very expensive and I would prefer 30 tablets to last 2 months not just 1. It may have been recommend that he takes the full 10mg per day because his behaviour at night (or when left alone) is quite severe and half a tablet may be ineffective.
You are right that the recommended dose is half a tablet daily for your dogs weight. However as you say his behaviour is quite severe and the bigger dose may be more helpful. You certainly won't overdose. You could try giving half a tablet daily and see what response you get on this dose. If it is not effective enough you can go up to 1 tablet daily.
What side effects can there be from selgian 10mg tablets for dogs?
Studies have shown that Selgian caused transient minor gastrointestinal irritation, e.g. salivation/ vomiting in 15/15000 administrations. It is also not recommended for use in pregnant or lactating bitches as it may interact with Prolactin and milk production.
my dog is already on akitivalt. is it safe to also give him selgian with these.
Yes it is safe to give Selgian with Aktivait. They have very different ingredients and do not interact adversely at all.
my american akita weighs 50kilos. he is 18mths old and fit.how much dosage will he need to help him chill out around people. thanks
The correct dose for your dog would be one and a quarter tablets daily. Ideally you should follow advice from a dog behaviour therapist at the same time, so as to get the maximum benefit from the tablets. He should become more receptive to being "trained" to improve, rather than hoping the tablets will do it all by themselves. (They might do, as long as you and the people he meets are able to respond appropriately to him. He needs to pick up the right signals from all of you to get the best benefit.)