Prepare for the fireworks season
TermaWorm launch Oct 17

Nobivac Lepto Injection for Dogs

  • Single Dose Lepto 2 for injection £2.99

Nobivac Lepto 4 is a liquid vaccine supplied in single dose bottles to protect dogs against Leptospirosis infection. It can be used as the diluent for Nobivac DHPPi in order to provide protection against additional diseases (Canine Distemper, Hepatitis, Parvo virus and Paranifluenza). Two injections given 4 weeks apart are needed for the first vaccination, which can start from 6 weeks of age. After that, a single booster vaccination needs to be given annually. (It is not necessary to boost for Distemper, Parvo and Hepatitis every year. These can be done on alternate years, or such longer period as advised by your veterinary surgeon.)


Inactivated, bacterial vaccine a liquid suspension of Leptospira interrogans serogroups

-Canicola (strain Ca-12-000) ≥ 40 PD80 /dose

-Icterohaemorrhagiae (strain 820K) ≥ 40 PD80 /dose

Also contains 0.1 mg/ml Thiomersal as a preservative. Each vial contains a single dose.


For active immunisation of dogs to reduce infection with Leptospira interrogans serovar canicola and Leptospira interrogans serovar icterohaemorrhagiae.

Specific claims

Nobivac Lepto 2 significantly reduces the number of animals which develop a urinary tract infection which can predispose to development of a carrier condition after L. canicola and L. icterohaemorrhagiae infection.

The duration of immunity induced by the vaccine was established as at least one year. Nobivac Lepto 2 can be used alone or as a diluent for other freeze dried Nobivac dog vaccines.

Dosage and administration

The contents of one vial (1 ml) should be administered by subcutaneous injection. Sterile equipment should be used for administration.

Primary course vaccination: All dogs not previously vaccinated should be vaccinated twice 2-4 weeks apart. Puppies should be at least 6 weeks of age before they receive the first vaccination.

Booster vaccination: A single annual booster dose is recommended.

Nobivac Lepto 2 may be used to reconstitute Nobivac DHPPi, Nobivac DHP, Nobivac Pi and Nobivac Parvo-C as indicated in the appropriate package leaflet.

The product may be used in pregnant bitches which have previously been vaccinated with Nobivac Lepto.

Contra-indications, warnings, etc

Only healthy dogs should be vaccinated.

A good immune response is reliant on the reaction of an immunogenic agent and a fully competent immune system. Immunogenicity of the vaccine antigen will be reduced by poor storage or inappropriate administration. Immunocompetence of the animal may be compromised by a variety of factors including poor health, nutritional status, genetic factors, concurrent drug therapy and stress.

A local reaction of limited size may occur during the first few days after vaccination.

After subcutaneous administration with the DHPPi, Pi, Parvo-C and/or Nobivac Rabies a diffuse swelling may be observed at the injection site in most puppies. Occasionally this swelling may be hard and painful but this will diminish gradually and will disappear after 2-3 weeks.

In the rare event of a hypersensitivity reaction following vaccination, administer an antihistamine, corticosteroid or adrenaline, without delay and by the most immediate route.

The vaccine may not be effective in dogs incubating the disease at the time of vaccination.

Some animals may be immunologically incompetent and fail to respond to vaccination. Animals that have received the corresponding anti-serum or immunosuppressive drugs should not be vaccinated until an interval of at least 4 weeks has elapsed.

Safety and/or efficacy data are available which demonstrate that this vaccine can be mixed with Nobivac DHPPi, DHP, Pi and/or Parvo-C.

Safety and/or efficacy data are available which demonstrate that this vaccine can be administered the same day but not mixed with Nobivac Rabies.

Do not mix with any other medicinal product except with the vaccines listed above.

For animal treatment only. Keep out of reach and sight of children.

Pharmaceutical precautions

Store at 2 to 8°C. Do not freeze. Protect from light.

In-use shelf life : 10 hours.

Disposal advice

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Legal category


Packaging Quantities

Cartons of 10 and 50 single dose vials or carton with one 10 ml vial.

Not all pack sizes may be marketed.

Further information


Marketing authorisation number

Vm 01708/4360.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:30pm
  • Sat: 9:00am - 1:00pm
  • Email:

All prices include VAT where applicable.

Reviews of Nobivac Lepto Injection for Dogs

Read our customers' reviews of Nobivac Lepto Injection for Dogs

Questions & Answers for Nobivac Lepto Injection for Dogs

Below are some recent questions we've received regarding Nobivac Lepto Injection for Dogs, including answers from our team.

Ask Your Own Question

Do I get card to put batch etc on for use in kennels

1st Mar 2016

Will I get card to prove dosage and batch for proof of cover for kennels

  • Non-Executive Director

If you ask separately for a vaccine card we can send one with your order at no extra charge. You have to do this or you will not get one. The vaccine itself comes in small bottles with a peel-off label which you can stick on the vaccine card. It states the name of the vaccine, the batch number and the expiry date (= use-by date for giving the vaccine, not how long the immunity lasts for). There is a place on the card for the person who gave the vaccine to sign. Normally your vet would sign here, but a vet should not sign if they did not give the vaccine. You can sign it yourself and as long as you do not put any false qualifications there, then the vaccine record card is correct, genuine and can be used. You must not pretend to be a vet, or that is actually against the law. It would be up to the kennels to decide if they wanted to accept a record card signed by you, though they might well not notice who signed it in fact.

Nobivac l4

12th Aug 2015
lesey michael

does lepto4 have to be given 4weeks apart. what time scale is there between injections

  • Non-Executive Director

Ideally it should be 4 weeks between injections which is on the data sheet. Some vets still use the same protocol as for Lepto 2, ie a minimum of 2 weeks and a maximum of 4 weeks between the two injections for an initial course. My guess is that this would be effective but it is not on the data sheet. early completion of the course to facilitate early socialisation and habituation is a factor to consider.