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Equest Pramox Horse Wormer

  • Equest Pramox Gel (Treats 700kg Horse) » 1 Syringe £20.12


Equest Pramox contains moxidectin and is one of the few wormers licensed to control the important encysted larval stages of small red worms. It has a long period of anti-worm activity after the dose has been given (13 weeks) and so helps to reduce pasture contamination. Equest Pramox is also less toxic to the natural beetles and other insects which help to break up the dung on the pasture, compared with ivermectin-based products. This means that pastures tend to remain cleaner and healthier where the dung is not collected from the field.

Equest Pramox also contains praziquantel which is provided for tapeworm control. Equest Pramox, in a single dose, controls the potentially dangerous small red worms, all other roundworms including pinworm, bots and all three types of tapeworm. One dose can be given every three months to protect the health of your horse, providing exceptionally good control of all these major parasites.

The presence of worms can be checked in your horse using a Worm Testing Kit.

Equest Horse Wormer is also available.

Equest Pramox Oral Gel


A pale yellow to orange/pink gel containing 19.5 mg/g moxidectin and 121.7 mg/g praziquantel as active ingredients and 220.0 mg/g benzyl alcohol and 0.80 mg/g butyl hydroxytoluene as preservatives/antioxidants.


Moxidectin is a second-generation macrocyclic lactone of the milbemycin family. Praziquantel is a parasiticide widely used in many species for the specific control of tapeworm. For the single dose treatment of mixed cestode and nematode or arthropod infections in horses and ponies, caused by moxidectin and praziquantel sensitive strains of:

Large redworm (large strongyles):

- Strongylus vulgaris (adults)

- Strongylus edentatus (adults)

- Triodontophorus brevicauda (adults)

- Triodontophorus serratus (adults)

- Triodontophorus tenuicollis (adults)

Small redworm (small strongyles/cyathostomin) (adults and intraluminal larval stages):

- Cyathostomum spp.

- Cylicocyclus spp.

- Cylicostephanus spp.

- Cylicodontophorus spp.

- Gyalocephalus spp.


- Parascaris equorum (adults)

Other roundworm species:

- Oxyuris equi (adults)

- Habronema muscae (adults)

- Strongyloides westeri (adults)

- Trichostrongylus axei (adults)


- Gasterophilus intestinalis (L2, L3)

- Gasterophilus nasalis (L2, L3)


- Anoplocephala perfoliata

- Anoplocephala magna

- Anoplocephaloides mamillana

The egg reappearance period of small redworm is 90 days.

The product is effective against (developing) intramucosal L4 stages of small redworm (strongyles). At 8 weeks after treatment, early (hypobiotic/inhibited) EL3 stages of small redworm (strongyles) are eliminated.

The product is effective against benzimidazole resistant strains of cyathostomes.

Dosage and administration

For oral administration.

One 14.4 g syringe contains sufficient gel to treat a 700 kg horse at the recommended dose rate (0.4 mg moxidectin per kg bodyweight and 2.5 mg praziquantel per kg bodyweight). Each graduation on the calibrated syringe delivers sufficient gel to treat 25 kg bodyweight.

Use of a scale or weight tape is recommended to ensure accurate dosing. To avoid overdosing, care should be taken to accurately dose foals, especially low bodyweight foals or pony foals.

Dosing guideline

The recommended dosing interval for the control of small redworm is 13 weeks. For optimum control of bots, the product should be administered in the autumn, after the end of the fly season and before spring as the larvae may start to pupate and therefore are less sensitive to treatment.

Veterinary advice should be given on appropriate dosing programmes and stock management to achieve optimum parasite control.

Contra-indications, warnings, etc

Horses must not be slaughtered for human consumption within 64 days of treatment.

Do not administer to young foals less than 6.5 months of age.

Do not use in cases of hypersensitivity to the active substance or to any of the excipients.

Equest Pramox Oral Gel is formulated specifically for use in horses only. Dogs or cats may be adversely affected by the concentration of moxidectin in this product if they are allowed to ingest spilled gel or have access to used syringes.

Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other on the same premises.

Operator Warnings

This product may cause eye irritation, skin irritation and skin sensitisation.

Avoid direct contact with skin and eyes.

The use of protective gloves is recommended.

Wash hands or any exposed area after use.

Do not smoke, drink or eat while handling the product.

In the event of eye contact flush the eye with copious amounts of clean water and seek medical advice.

In case of accidental ingestion, seek medical help and show the doctor the package insert.

Environmental safety

In order to limit the impact of moxidectin on dung fauna, and due to insufficient data regarding environmental risk of praziquantel, horses should not be turned out onto pasture within 3 days of treatment.

Equest Pramox Oral Gel is toxic to fish and aquatic organisms. Do not contaminate ponds, waterways or ditches with product or used syringes. Any unused veterinary medicinal products or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Pharmaceutical precautions

Do not store above 25°C.

Use within 6 months after opening.

Do not use after the expiry date stated on the carton after "EXP".

Keep out of the reach and sight of children.

For animal treatment only.

Legal category

Packaging quantities

HDPE syringe containing 14.4 g of gel with graduated polypropylene plunger and LDPE cap.

Further information

Care should be taken to avoid the following practices, because they increase the risk of development of resistance and could ultimately result in ineffective therapy:

- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time;

- Under-dosing which may due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).

- Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Parasite resistance to a particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.

The veterinary surgeon should give advice regarding appropriate dosing programmes and stock management to achieve adequate parasite control for both tapeworm and roundworm infestations.

In the case of cestode treatment the dose of praziquantel in the product has been selected at the top end of the dosing range.

Flaccid lower lip, ataxia and swelling of the muzzle could be observed on rare occasions in young animals. These adverse effects are transient and disappear spontaneously. In adults transient adverse reactions may occur at 3 times the recommended dose. The symptoms are depression, inappetence, ataxia, flaccid lower lip in the 8 to 24 hours following treatment. Symptomatic treatment is not generally necessary and recovery is generally complete within 24 to 72 hours.

There is no specific antidote.

In case of very high worm burdens, destruction of the parasites may cause a mild transient colic and loose faeces in the treated horse.

Equest Pramox Oral Gel is specially formulated to be easily expelled by the syringe plunger. Once in the horse?s mouth, Equest Pramox Oral Gel liquefies. This facilitates dosing and reduces the risk of rejection.

Equest Pramox Oral Gel has been shown to be safe for use in breeding, pregnant and lactating mares. Administration does not adversely affect the fertility of mares.

Marketing Authorisation Number

Vm 42058/4058

Significant changes


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Reviews of Equest Pramox Horse Wormer

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Questions & Answers for Equest Pramox Horse Wormer

Below are some recent questions we've received regarding Equest Pramox Horse Wormer, including answers from our team.

Ask Your Own Question

Lung worm

25th Sep 2016
Karen Hare
  • VioVet Customer Since: August 2016
  • From: West Midlands, United Kingdom

Will Equest pramox get rid of lung worm? Have just bought a new horse and vet thinks she has lung worm, we haven't got much history for her but believe she could have been kept with donkeys and cattle,

  • Veterinary Surgeon

Lungworm are susceptible to the Macrocyclic Lactones such as ivermectin and moxidectin. Equest Pramox contains moxidectin so is effective against lungworm. It also contains Praziquantel effective against tapeworms which is a good idea for this time of year. However if you do not wish to treat for tapeworm at the moment you can use just Equest which is moxidectin only.

Pregnant horse

13th Jul 2016
Stacey Algie
  • VioVet Customer Since: September 2014
  • From: Cheshire, United Kingdom

Can I give this to a pregnant mare please

John Cousins
  • Veterinary Surgeon

Equest Pramox Oral Gel has been shown to be safe for use in breeding, pregnant and lactating mares. Administration does not adversely affect the fertility of mares.

Equest Paramox v Panacur Guard

6th Oct 2015
Field 1

Do you need to keep horses in when administering either Equest Paramox or Panacure Guard 5 day wormer??
Do they kill the worm in situ or just expel the worms.

Danielle Fletcher
  • Category Manager, Own Brand & E-SQP

There's no need to keep your horses stabled while using these products. It used to be common practice, although nowadays it is not thought to be necessary. However, if you rotate your pastures, you can keep your horses on the same field for 2/3 days after worming, before moving onto fresh pasture and resting the original.

Equest Pramox contains two active ingredients, moxidectin to target roundworm (including encysted small redworm larvae) and bots, and praziquantel to target tapeworm. Moxidectin causes flaccid paralysis and starvation of the parasites. Parasites in the lumen of the gut will be passed out either dead, or in a paralysed state which they will not survive. Encysted redworm larvae in the lining of the gut are not passed out, they die in situ and are broken down and absorbed. Praziquantel causes spastic paralysis of tapeworm, which means that they go rigid and can no longer move, or hold their position in the gut. If they are not dead when they are passed out, they will soon be.

Panacur contains a chemical called fenbendazole, which kills worms through blocking their ability to carry out vital processes such as absorbing food and excreting waste.