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EasOtic is used to treat common types of ear trouble in dogs. It contains ingredients to kill the bacteria and yeasts (especially Malassezia) found in large numbers in most cases of canine otitis, as well as an anti-inflammatory agent to reduce discomfort, swelling and further discharge within the ear canal. EasOtic is presented in a bottle with a pump action which quietly, comfortably and easily delivers the correct dose of medication (1ml) into the ear canal. Once daily dosing for 5 days is normally recommended. If there is a significant amount of wax or discharge within the ear canal, it is very helpful to use a water-based ear cleaner first. Once the ear canal has been cleaned, it should be left to dry before EasOtic is applied. Sometimes it is also helpful to clip excess hair away from the opening to the ear canal first.
All prices include VAT where applicable.
Ear drops suspension for dogs containing:
Hydrocortisone aceponate 1.11mg/mL
Miconazole as nitrate 15.1mg/mL
Gentamicin as sulfate 1505IU/mL
Treatment of acute otitis externa and acute exacerbation of recurrent otitis externa associated with bacteria susceptible to gentamicin and fungi susceptible to miconazole in particular Malassezia pachydermatis.
Auricular use. One mL contains 1.11mg hydrocortisone aceponate, 15.1mg miconazole (as nitrate) and 1505 IU gentamicin (as sulfate).
It is recommended that the external ear canal should be cleaned and dried before treatment and excess hair around the treatment area be cut.
Shake the bottle thoroughly before first administration and prime the pump.
The recommended dosage is 1mL of the veterinary medicinal product per ear once a day for five consecutive days.
Introduce the atraumatic canula in the ear canal. Administer one dose (1mL) of the product in each affected ear. This dose is adequately delivered by one pump activation. The airless pump allows the product to be administered whatever the position of the bottle is.
After application, the base of the ear may be massaged briefly and gently to allow the preparation to penetrate to the lower part of the of the ear canal. The product as presented allows treating a dog suffering from bilateral otitis. The veterinary medicinal product should be used at room temperature (i.e. do not instil cold product).
Do not use in cases of hypersensitivity to the active substances or to any of the excipients, to corticosteroids, to other azole antifungal agents and to other aminoglycosides.
Do not use if the eardrum is perforated.
Do not use concurrently with substances known to cause ototoxicity.
Do not use in dogs with generalised demodecosis.
Bacterial and fungal otitis is often secondary in nature and appropriate diagnosis should be used to determine the primary factors involved.
Special precautions for use
Special precautions for use in animals
If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate therapy instituted. Use of the veterinary medicinal product should be based on identification of infecting organisms and susceptibility testing and take into account official and local antimicrobial policies.
Use of the veterinary medicinal product deviating from the instructions given in the SPC may increase the prevalence of bacteria and fungi resistant to gentamicin and miconazole respectively and may decrease the effectiveness of treatment with aminoglycosides and azole antifungal agents, due to the potential for cross-resistance.
In case of parasitic otitis, an appropriate acaricidal treatment should be implemented. Before the veterinary medicinal product is applied, the external auditory canal must be examined thoroughly to ensure that the ear drum is not perforated in order to avoid the risk of transmission of the infection to the middle ear and to prevent damage to the cochlear and vestibular apparatus.
Gentamicin is known to be associated with ototoxicity when administered by the systemic route at higher doses.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental skin contact, it is recommended to wash thoroughly with water.
Avoid contact with eyes. In case of accidental contact, rinse with abundant quantities of water. In case of eye irritation, seek medical advice. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Adverse reactions (frequency and seriousness)
Mild to moderate redness of the ear was common (2.4% of treated dogs). Papules were observed uncommonly (less than 1% of treated dogs). In all cases, treatment with the veterinary medicinal product was not discontinued and all dogs recovered without any specific therapy.
In very rare cases, the use of the veterinary medicinal product has been associated with hearing impairment (partial hearing loss or deafness), usually temporary, and primarily in geriatric dogs. If this occurs, treatment should be stopped.
In very rare cases, type-I hypersensitivity reactions (facial swelling, allergic pruritus) have been observed. If this occurs, treatment should be stopped.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports.
Use during pregnancy, lactation or lay
The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Systemic absorption of hydrocortisone aceponate, gentamicin sulphate and miconazole nitrate being negligible, it is unlikely for teratogenic, foetotoxic or maternotoxic effects to occur at the recommended dosage in dogs. Use only accordingly to the benefit-risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
Compatibility with ear cleaners has not been demonstrated.
Keep out of the sight and reach of children. This medicinal veterinary product does not require any special storage conditions. Do not use after the expiry date stated on the label. Once open use within 10 days.
Box containing 1 multidose container (the content of 10mL is equivalent to 10 doses).
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