Protexin Denamarin Liver Support for Cats and Dogs

Protexin Denamarin Liver Support for Cats and Dogs
90mg Tablets (Cat/Small Dog) » Pack of 30
225mg Tablets (Med Dog) » Pack of 30
425mg Tablets (Large Dog) » Pack of 30

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  • 90mg Tablets (Cat/Small Dog) » Pack of 30 £27.99
  • 225mg Tablets (Med Dog) » Pack of 30 £46.99
  • 425mg Tablets (Large Dog) » Pack of 30 £68.99

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£27.99 to £68.99

Description

Protexin Denamarin is a dietary supplement containing a stabilised form of the SS-SAMe (S-adenosylmethionine) isomer and silybin complexed with phosphatidylcholine for cats and dogs.

Tablets should be given on an empty stomach at least one hour before a meal for optimum absorption (an overnight fast is preferred).

Once the tablet has been administered, allow at least 1 hour before feeding your pet.

The number of tablets administered may gradually be reduced, or increased, at any time at the recommendation of your veterinary surgeon.

Cats and Dogs under 5kg administer 1 x 90mg tablet daily

Dogs 5kg -15kg administer 1 x 225mg tablet daily

Dogs 15kg-30kg administer 1 x 425mg tablet daily

Dogs 30kg-55kg administer 2 x 425mg tablets daily

Dogs over 55kg administer 3 x 425mg tablets daily

The tablets should not be split or crumbled. Keep tablets in original blister pack until used.

Store in a cool, dry place

Product Composition 90mg Tablets
SAMe 90mg, Silybin 9mg, Additives; Methionine as S-adenosylmethionine, Composition; Silybin phytosome (Milk thistle extract/ Phosphatidylcholine complex), Mannitol.
Product Composition 225mg Tablets
SAMe 225mg, Silybin 24mg, Additives; Methionine as S-adenosylmethionine, Composition; Silybin phytosome (Milk thistle extract/ Phosphatidylcholine complex), Mannitol.
Product Composition 425mg Tablets
SAMe 425mg, Silybin 35mg, Additives; Methionine as S-adenosylmethionine, Composition; Silybin phytosome (Milk thistle extract/ Phosphatidylcholine complex), Mannitol.

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Reviews (66)

Summary of Reviews for Protexin Denamarin Liver Support for Cats and Dogs

Overall 5
Effectiveness
Ease Of Use
Value For Money
Absence Of Side Effects
64 out of 66 (97%) customers would recommend this product.
5 stars (45 reviews)
4 stars (16 reviews)
3 stars (2 reviews)
2 stars (1 reviews)
1 stars (2 reviews)

Only verified purchasers of this product can leave a review.

Denamarin
Verified Purchase

By Barry Crombleholme on 18 October 2025

Works for my dog, keeps her well !

Customer recommends this product

Great service
Verified Purchase

By Janet Gray on 5 March 2025

Helping my pooch

Customer recommends this product

Working well
Verified Purchase

By Helen Clifton on 22 July 2024

So far so good , baileys been taking this for a month now

Customer recommends this product

Liver supplements
Verified Purchase

By Susan Chappelow on 25 June 2024

Delivery was prompt. My dog does like taste of tablets first tablets he has refused but chicken paste smeared on works. Product is as advertised. Awaiting for his next blood test to assess if working, so far so good. They are expensive but seem to be best available recommended by my vet.

Customer recommends this product

Recommended by our vets and seems to be a good supplement
Verified Purchase

By Catherine Armstrong on 2 April 2024

Our elderly bitch had some health issues flagged up in her bloods and the vet suggested this supplement, which seems to have helped.

Customer recommends this product

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Q & A

Below are some recent questions we've received regarding Protexin Denamarin Liver Support for Cats and Dogs, including answers from our team.

22 February 2025 at 9:15am

Dosage

Lucy

What is the dosage? One tablet per day or more?

  • VioVet Staff
  • Dogs
    <5kg 1 small tablet daily

  • Dogs
    5-15kg 1 medium tablet daily

  • Dogs
    15-30kg 1 large tablet daily

  • Dogs
    30-55kg 2 large tablets daily

  • Dogs

    55kg 3 large tablets daily

25 November 2024 at 4:22pm

Denamarin storage

JOHN

Do I have to store these tablets at a special temperature ie in a fridge etc.

  • VioVet Staff

Store in a cool, dry place. Keep tablets in original blister pack until used. The tablets should not be split or crumbled.

22 December 2021 at 7:43pm

Puppy

Sally Embley

Hi can I give this to a 12 week old Deerhound puppy with liver shunt? Thanks

  • VioVet Staff

There is no reason this supplement will not be safe for supporting a 12 week old puppy's liver, however you should only give supplements/food/medication alongside your vets advice if they have a liver shunt. Changes to the diet can affect the condition depending on the severity so it is important your vet approves the use beforehand.

2 November 2021 at 10:22pm

Which one to give

MRS TRACEY J MASTERS

my dog is 9.7kg which tablet should he have please

  • VioVet Staff

Your 9.7kg will need the Medium sized Denamarin tablets.

14 March 2018 at 1:16am

Giving Denamarin tablet

Dexter

I find it very difficult to get my dog to take the tablet. Sometimes it takes two or three attempts, by which time the tablet is losing its coating. Will this make any difference to the tablet's effectiveness? We have sometimes given it with a small amount of food, is this a problem?

  • VioVet Staff

The enteric coating of Denamarin protects the SAMe from degradation in the stomach so that the maximum amount can be absorbed in the small intestine. If the coating is lost then it is likely to be less effective. It is better as you say to give with a very small amount of food then give a main meal one hour later.

16 February 2017 at 6:27pm

Protexin Denamarin

Amanda Lloyd

Is Protein Denamarin a better option then Hepatosyl plus for liver problems?

  • VioVet Staff

Both products contain very similar ingredients. However it is thought that Denamarin is more bio-available so more of the product is absorbed and used by the body. Although, to my knowledge there have not been any studies which compare the two so it is difficult to say with certainty that Denamarin is better.

19 September 2015 at 10:47am

Denamarin with food

Dan Jackson

  • VioVet customer since 2015
  • From: Sir Benfro, United Kingdom

Hello, as per the guidelines we give our Jack Russell the Denmarin 1 hour before eating, always in the morning. shortly we will be leaving her at a kennel for 8 days, will administering it with food be an issue for this short period. Some neighbours of ours always give it with food? Many thanks. Dan

  • VioVet Staff

Giving it with food is often what people have to do, though it is less good than doing it as recommended. It will reduce the effectiveness of that particular dose, because the active ingredient will not be absorbed fully from the gut and will "come out the other end" without ever getting to the liver. However some will be absorbed and for a short period of a few days it is unlikely to make a noticeable difference. Ideally ask the kennels to give the medication with a minimal amount of food, then give a meal later. If they cannot then it should not be a disaster.

23 April 2014 at 5:58pm

Prescription?

JEAN FONE

Is a prescription required for Denamarin?

  • VioVet Staff

No, Protexin Denamarin can be bought without the need for a prescription.

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