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Oxytetracycline is active against a wide range of Gram-positive and Gram-negative pathogenic bacteria, certain rickettsia and the larger viruses. Alamycin 10% Injection is indicated in the treatment of a wide range of common systemic, respiratory and local infections caused by or associated with organisms sensitive to Oxytetracycline in cattle and pigs.
is a bacteriostatic antibiotic that inhibits protein synthesis in susceptible bacteria. Inside the cell it binds irreversibly to receptors on the 30S subunit of the bacterial ribosome where it interferes with the binding of the amino-acyl transfer RNA, to the acceptor site on the messenger RNA ribosome complex. This effectively prevents the addition of the amino acids to the elongating peptide chain, inhibiting protein synthesis.
Oxytetracycline is a bacteriostatic antibiotic that inhibits protein synthesis in susceptible bacteria. Inside the cell it binds irreversibly to receptors on the 30S subunit of the bacterial ribosome where it interferes with the binding of the amino-acyl transfer RNA, to the acceptor site on the messenger RNA ribosome complex. This effectively prevents the addition of the amino acids to the elongating peptide chain, inhibiting protein synthesis. Without the process of protein synthesis taking place, the cell is unable to grow and repair.
33 mg/g Oxytetracycline (as the hydrochloride) in 140g aerosol spray can
An aid in the treatment of foot rot in sheep, digital dermatitis in cattle and superficial skin infections caused by oxytetracycline sensitive organisms in pigs, sheep and cattle.
SHAKE WELL BEFORE USE. Before spraying, the infected area should be cleansed and hooves should be pared. Holding the can upright, spray at a distance of 10 - 15 cm for a minimum of 5 seconds or until the area is covered.
Treated cattle and sheep should be allowed to stand on dry ground for 1 hour before returning to pasture.
Avoid milk contamination. Wash thoroughly from teats and udders prior to milking.
Store below 25°C (Air Conditioning) in a dry place out of direct sunlight.
Aerosols should be completely emptied before disposal. Place empty can in household rubbish. DO NOT PUNCTURE OR INCINERATE.
Oxytetracycline is active against a wide range of
gram-positive and gram-negative pathogenic bacteria. In
severe infections, topical treatment should be
supplemented with systemic antibiotic treatment.
EXPORT SLAUGHTER INTERVAL (ESI): Animals can be
slaughtered for export at zero days after the last
SAFETY AND FIRST AID INSTRUCTIONS:
If poisoning occurs, contact a doctor or Poisons
Information Centre (Ph: 131126). Keep away from eyes.
Avoid inhalation. Wash hands after use.
Store below 25°C (Air Conditioning) in a dry place out of
APVMA Approval No.: 47532
A sterile aqueous solution containing:
Oxytetracycline Dihydrate equivalent to 200mg/ml of oxytetracycline base.
Sodium Formaldehyde Sulphoxylate Dihydrate (0.4%w/v).
Alamycin LA is specifically formulated to provide a prolonged action resulting in sustained antibacterial activity. Blood levels persist for at least 4 days. After administration by the intramuscular route maximum blood levels are achieved after 4 to 8 hours making Alamycin LA suitable for the treatment of acute infections.
Oxytetracycline has been shown to be effective in vitro against the following bacterial species: Bordetella bronchiseptica, Arcanobacterium pyogenes, Erysipelothrix rhusiopathiae, Escherichia coli, Haemophilus somnus, Mannheimia haemolytica, Pasteurella multocida, Salmonella dublin, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus faecalis, Streptococcus pyogenes and Streptococcus uberis.
Alamycin LA is indicated for use in cattle, sheep and pigs in the treatment of: atrophic rhinitis caused by Bordetella bronchiseptica, Mannheimia haemolytica and Pasteurella multocida; navel/joint ill caused by Arcanobacterium pyogenes, E. coli, and Staphylococcus aureus; mastitis caused by Arcanobacterium pyogenes, E. coli, Staphylococcus aureus, Streptococcus agalactiae, and Streptococcus uberis;metritis caused by E. coli and Streptococcus pyogenes; pasteurellosis and infections of the respiratory tract caused by Mannheimia haemolytica and Pasteurella multocida; septicaemia caused by Salmonella dublin and Streptococcus pyogenes; erysipelas caused by Erysipelothrix rhusiopathiae.
Alamycin LA can also be used in the control of enzootic abortion in sheep.
The recommended dosage rate is 20mg/kg bodyweight (1ml per 10kg bodyweight) by deep intramuscular injection. The product is recommended for a single administration only.
Milk for human consumption: Milk taken from cows should not be used for human consumption during treatment or for 10 days after treatment. Sheep’s milk may not be used for human consumption during treatment or for 7 days after treatment.
Meat for human consumption: Cattle, Sheep and Pigs must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 31 days from last treatment and Sheep only after 9 days from last treatment. Pigs may be slaughtered for human consumption after a period of 18 days following last treatment.
When the container is broached for the first time, the date on which any product remaining in the container should be discarded should be calculated and recorded.
A statement of the in-use shelf life of the product is given on the package insert. This discard date should be written in the space provided on the primary label.
Do not dilute Alamycin LA. Although Alamycin LA is well tolerated, occasionally a slight reaction of a transient nature has been observed. The use of tetracyclines during the period of tooth and bone development, including late pregnancy, may lead to discolouration. If concurrent treatment is administered, use a separate injection site. Wash hands after use. In case of contact with eyes or skin, wash immediately with water as irritation may occur. Take care to avoid accidental injection.
Do not store above 25ºC. Protect from light. Following withdrawal of the first dose, use the product within 28 days. Discard unused material. Keep container in outer carton. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
If stored as directed Alamycin LA can be expected to retain its potency for 2 years from the manufacturing date.
When the vial has been broached and the contents exposed to air, the solution may darken but the potency will be unchanged.
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