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Advantage 400 Spot On Flea Control Extra Large Dog

Advantage 400 Spot On Flea Control Extra Large Dog Advantage 400 Spot On Flea Control Extra Large Dog Advantage 400 Spot On Flea Control Extra Large Dog
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400 Extra Large Dogs Over 25kg » 4 Pipettes 400 Extra Large Dogs Over 25kg » 4 Pipettes 400 Extra Large Dogs Over 25kg » 4 Pipettes

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  • Special Offer 400 Extra Large Dogs Over 25kg » 4 Pipettes £8.14


Why Worry about fleas?

Fleas can cause more than just irritation in dogs; they can lead to flea allergy dermatitis (FAD) or even anaemia (if it’s a severe infestation). Some pets develop allergies to flea saliva, which means even a few bites can lead to severe itching and sore skin infected fleas can also transmit tapeworm if swallowed during grooming. All very nasty stuff.

What’s more, fleas don’t just bite your furry friend, they bite humans too and can infest your home causing irritation to you and your family. Did you know it can take months to get rid of a infestation in your home as only 5% of fleas lice on tour pet, the other 95% are in your home environment as eggs, larvae and pupae.

One application of advantage, the vet-recommended flea treatment, with its fuss-free pipette application gets to work within one day and remains effective for up to four weeks. Advantage is able to kill fleas through contact, no biting required. *

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:00am - 6:00pm
  • Sat: 9:00am - 1:00pm
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

Reviews (1320)

Summary of Reviews for Advantage 400 Spot On Flea Control Extra Large Dog

Overall 5
Ease Of Use
Value For Money
Absence Of Side Effects
1292 out of 1320 (98%) customers would recommend this product.
5 stars (1116 reviews)
4 stars (171 reviews)
3 stars (8 reviews)
2 stars (5 reviews)
1 stars (20 reviews)

Only verified purchasers of this product can leave a review.

55 Excellent
Verified Purchase

By on 21 July 2020

Works fantastic

Customer recommends this product

55 Flea and tic prevention
Verified Purchase

By on 9 July 2020

Does the job required.

Customer recommends this product

55 flea away!
Verified Purchase

By on 31 May 2020

I have used it before and it's totally fine and at a very reasonable prive!

Customer recommends this product

55 Flea treatment
Verified Purchase

By on 21 May 2020

Seems to have worked, fingers crossed

Customer recommends this product

55 Advantage spot on flea control
Verified Purchase

By on 19 May 2020

Excellent product

Customer recommends this product

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Q & A

Below are some recent questions we've received regarding Advantage 400 Spot On Flea Control Extra Large Dog, including answers from our team.

20 October 2018 at 7:06pm

Active ingredient

Lynn Whitlock

Please could you tell me what the active ingredient in Advantage flea control is please?

  • VioVet Staff

Hi Lynn,

Thanks for your enquiry.

The active ingredient is: imidacloprid

I hope this helps.

31 July 2018 at 2:08pm

Flea treatment for nursing bitch and pups


Can u use this product on a nursing bitch and one week old puppies

  • VioVet Staff

Hello Danielle,

Thank you for your question.

It is safe to apply to lactating females and doing this will treat the puppies or kittens as well as the adult, and can be used on dogs from 8 weeks old.

Hope that helps,


21 July 2018 at 11:38pm

Harvest Mites


Can Advantage kill harvest mites?

  • VioVet Staff

Hi Jennie,

Advantage treats fleas (on cats and dogs) and biting lice (on dogs) only.

Hope this helps.

8 June 2018 at 11:35am

Nursing Cat


Can I use this on my cat who is nursing 2 week old kittens?

  • VioVet Staff

Hello Emma,

Thank you for your question.

Yes you can use the Advantage flea control on your cat while she is nursing her kittens.

Hope this helps.

29 March 2018 at 5:12pm

Does this product need a prescription?

Jacqueline Hall

  • VioVet customer since 2013
  • From: Hampshire, United Kingdom

Does this product need a prescription?

  • VioVet Staff

No you do not need a prescription for Advantage but you do for Advantix.

6 December 2017 at 12:58pm

When can I use an alternative?

Geraldine Sayers Cowper

  • VioVet customer since 2017
  • From: Norfolk, United Kingdom

Advantage has stopped working on my elderly cat (20yrs old). How soon can I use an alternative - I applied Advantagge 2 weeks ago and she still has fleas.

  • VioVet Staff

It should be safe to try an alternative now if it has been 2 weeks since she last had Advantage. However it is unlikely that the Advantage has stopped working but that you need to treat the house too with a spray such as Indorex. Fleas hide in carpets, curtains, furniture, pet bedding etc and then can jump back onto your cat. Even if your cat has been treated it will take around 24hrs before the fleas are killed.

30 November 2017 at 1:31pm

Suitable for Guinea pigs?

Samantha Batty

Brought the Guinea pigs in for winter and I really don't want the cats to get fleas. Will this dosage be suitable for Guinea pigs?

  • VioVet Staff

Hello Samantha, t

Thank you for your question.

Unfortunately this product is not suitable for use on guinea pigs as it is only licensed for use on dogs, cats or rabbits.

We would recommend checking out the Xeno 450 Spot-On Parasite & Flea Treatment to treat guinea pigs for fleas. Here is a link to the product page:

I hope that helps.

19 November 2017 at 3:34pm

Puppy flea treatment


I am looking for advantage puppy flea treatment for a twelve week old puppy weighing approximately 12 kilos do you sell it and for how much?

  • VioVet Staff

Advantage is safe to use on puppies from 8 weeks old. If your puppy is 12kg then you will need Advantage 250 spot-on.

3 November 2017 at 9:41pm

Age of kitten vs weight


I have kitten who is 8 1/2 weeks. Is it definitely safe to use on her or does she have to be at least over a certain weight. I only ask cause my older cat had treatment when he was 8 weeks from something else, which said from 8 weeks so gave it to him only for him to nearly die :( as one dose overdosed him, later found out they were for from 8 weeks but from a certain weight :(

  • VioVet Staff

There is nothing on the Advantage data sheet to say there is a minimum weight at which it can be used, just that kittens should be over 8 weeks old, so it should be fine. However, if you are concerned you could use Fiproclear Spray instead which is suitable for use on all sizes of dog and cat from 2 days old.

13 October 2017 at 2:27pm

Fur mites


Will this help with fur mites on rabbit?

  • VioVet Staff

Hi Chelsea,

Thanks for your question. Advantage wont treat mites, I'm afraid. You could try Pharmaq Ivermectin for small animals (item no 149772).

Kind regards,


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