Adaptil Calm Home Diffuser Refill

Adaptil Calm Home Diffuser Refill
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3 x 48ml Refill Vials
48ml Refill Vial

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  • 3 x 48ml Refill Vials £61.00
  • 48ml Refill Vial £25.59

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£25.59 to £61.00


This ADAPTIL® Calm Plug-in Diffuser Refill, when inserted into the ADAPTIL® Calm Plug-in Diffuser Refill, slowly releases the soothing pheromone into the air letting your dog feel at ease.

In the natural environment, puppies and adult canines join together and exchange natural messages delivered into the air - pheromones.

  • These relaxing messages are secreted by mother dogs throughout lactation and around mature dogs' ears.

The ADAPTIL® Calm Plug-in Diffuser gives your dog this soothing pheromone, which you can't yourself: contributing to their well-being and helping them adapt to stressful situations.

Key Benefits

  • Easy to use
  • Each diffuser refill covers an area up to 70 m2
  • Creates a reassuring environment at home
  • Scientifically proven
  • Veterinary used and recommended
  • Each refill lasts for 30 days

Directions for Use

Just plug and play: turn the vial into the diffuser unit and plug it into an electric socket. Ideally, in the area where your dog spends most of its time.

The area covered by the pheromones is up to 70m2 per single Adaptil 48ml Refill Vial.

Avoid plugging in the diffuser under shelves, behind doors, behind curtains or behind furniture, as it will not work.

The diffuser needs to be switched on 24/7. Many dog owners begin to see results within seven days. However, every dog is unique. It may take longer to improve depending on the time the signs have been apparent and how severe they are.

We recommend using ADAPTIL® Calm Plug-in Diffuser for at least one month.

Need help or advice? Contact us:

All prices include VAT where applicable.

Reviews (296)

Summary of Reviews for Adaptil Calm Home Diffuser Refill

Overall 4
Ease Of Use
Value For Money
Absence Of Side Effects
241 out of 296 (81%) customers would recommend this product.
5 stars (164 reviews)
4 stars (53 reviews)
3 stars (28 reviews)
2 stars (18 reviews)
1 stars (33 reviews)

Only verified purchasers of this product can leave a review.

55 Adaptil
Verified Purchase

By on 16 July 2023

Very good.

Customer recommends this product

55 Very distressed greaving dog!
Verified Purchase

By on 20 February 2023

This product used beside Zylkene definitely helped to get my grief stricken wee dog after the loss of two lifetime doggy friends. Calmed down now slowly returning to better state of mind.

Customer recommends this product

45 Its a refill
Verified Purchase

By on 20 October 2022

Purchased refill for use round 5/11/22 and Xmas. Worked well last year to keep my dogs calm at those times

Customer recommends this product

55 Excellent
Verified Purchase

By on 23 February 2022

I use this regularly for my dogs and I have to say it works well. It helps keep them calm and relaxed.

Customer recommends this product

45 Works well for our whippet who panics +++++ when fireworks go off
Verified Purchase

By on 4 December 2021


Customer recommends this product

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Q & A

Below are some recent questions we've received regarding Adaptil Calm Home Diffuser Refill, including answers from our team.

30 September 2021 at 12:00pm

Is it safe for a kitchen?

Jemima Read

  • VioVet customer since 2014
  • From: East Sussex, United Kingdom

Can I use the diffuser in an area where there is food preparation?

  • VioVet Staff

Yes the diffuser can be used in your kitchen. According to the toxicological data on the components of Adaptil,
no particular risk is expected following inhalation of the pheromone
products when used as recommended. The ingredient itself is a dog pheremone that is naturally produced by female dogs 3-5 days after birth to calm the puppies. There is no indication to say that this should interfere with food or be an issue with humans.

25 September 2017 at 2:35pm

Can u use more than one at a time

Paula Gray

  • VioVet customer since 2017
  • From: Hampshire, United Kingdom

Hi we recently homed a dog from blue cross who put adaptil collars on their dogs before leave is it ok to put the disfusser plug in the house as well or it to much for the dog?

  • VioVet Staff

Hi Paula,

Thank you for your question. It is perfectly fine to use the diffuser plug-in together with the collars.

I hope this helps.

17 April 2017 at 2:19pm

How to use spray

Brian millar

Hi do you spray directly onto dog or onto collar and how much do you use

  • VioVet Staff

Hi Brian,

Adaptil Spray should only be applied to an environment a dog will be in eg a crate, car, kennel etc, and cannot be sprayed directly onto the dog. If you'd like your dog to have support from Adaptil at all times (inside and outside the house), I'd recommend trying the Adaptil Collars.

Adaptil Spray is great for short-term support like vet trips and car journeys. The effects last 4-5 hours and the spray must be applied to the area (8-10 pumps) about 15 minutes before the dog is introduced. Waiting 15 minutes lets the alcohol the pheromone is delivered in evaporate. The full usage instructions can be found in the description tab here on our website. There is also a section called 'Not sure which Adaptil product to use?' which will show you which of the products are recommended for your situation eg a new puppy/nervous when travelling/ fear of loud noises/ separation anxiety etc.

I hope this helps!

10 February 2017 at 2:20pm

Does size matter?


Hi, I have the plug in which currently has the 48ml bottle in it. Would the larger bottle fit in the same plug in unit or they come in different sizes too?

Thanks in advance!

  • VioVet Staff

Hi Kelley,

The only size refill vial is the 48ml one. The Adaptil Spray is 60ml but that is just a spray and doesn't go in the diffuser unit.

I hope this helps.

11 January 2017 at 10:01pm

Heart murmur affected?

Heart murmur

One of my dogs (not the one with the issues) has a heart murmur. Is this product suitable to be used around her?

  • VioVet Staff

Hi there,

There should be no problems whatsoever as Adaptil is a natural product containing a synthetic copy of the dog appeasing pheromone. It is non-sedative, non-systemic and can be used alongside other types of medication. If you need any further advice, we would advise contacting the manufacturer, Ceva, about it.

I hope this helps.

22 September 2016 at 10:11pm

Dap 48ml lasts how long?

Marina Hunter-Gray

  • VioVet customer since 2013
  • From: West Yorkshire, United Kingdom

See above please?

  • VioVet Staff

The 48ml refills last 4 weeks on average but it can vary slightly depending on air flow in the room, temperature etc. The diffuser itself should be replaced every 6 months.

14 August 2015 at 4:29pm

Would this affect my budgie

affect other animal's

Would this product affect my budgie or is it safe with birds

  • VioVet Staff

This is completely fine to use with birds. It is true that birds are often particularly sensitive to inhaled toxic substances, but the Adaptil products are perfectly harmless to all species.

11 August 2015 at 10:40pm

Pregnant wife


My wife is pregnant and the dog appears to have seperation anxiety. Please can you recommend a product whuch is safe to be around my wife. Thanks

  • VioVet Staff

Adaptil is perfectly safe for your wife, and could certainly help with the anxiety. You could try giving the dog Zylkene too if needed. It should be perfectly safe for your wife to handle that too. Separation anxiety can be helped a great deal by the way the dog is managed around the times it is left so you should seek some expert advice about this. Probably there is good information online, or perhaps even contact to get some help.

27 April 2015 at 10:48am

Dosage of Tablets for a GSD dog

sally mackenzie

Going to Ireland, might be a rough crossing!! she is normally OK on ferry to France although appeared a little 'stressed' once so we went Euro tunnel next. She does travel well but is now 9 years old. Only medication she has every other day is Metacam. Travelling 9th.May .15. thanks.

  • VioVet Staff

I would give 3 tablets to her 2 hours before you travel. The dose can be repeated 6 hours later.

31 December 2014 at 3:51pm

Adaptil tablets


How long do the tablets last?

  • VioVet Staff

These tablets are a new addition to the range and we have not yet had any feedback into how effective they are.

The effect would be expected to last for a few hours. If a longer duration of effect is wanted, then they should be combined with one of the pheromone products. A further tablet dose can be given 6 hours or so later if needed.

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