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Zylkene is a complementary feed for dogs, cats and horses (for horse version click here) which contains a natural product, derived from casein, a protein in milk. It is a molecule well known to promote the relaxation of newborns after breastfeeding. Launched in April 2008, Zylkene has become a familiar product for veterinary surgeons, behaviourists, nurses and pet owners for use in helping pets cope when facing unusual and unpredictable situations or before occasions such as a change in their normal environment.
Zylkene is a product that can help support dogs, cats and horses in situations where they find the need to adapt their behaviour to cope. These include kennel and cattery stays, house moves, kennel/box rest, arrival of a new pet or baby, sudden noises e.g. fireworks, travel, vet or groomer visits and Christmas festivities.
There are many ways our pets can respond to new and unpredictable situations and not all animals respond in the same way. Zylkene is palatable and easy to give; simply mix with food or give as a treat. Give just once a day.
There are many reports in the literature of remarkably good responses to Zylkene. In dogs and cats it is particularly good for travel, re-homing, grooming, visiting the vets etc. For horses, Zylkene Equine can easily be given in feed for clipping, travelling, shoeing etc.
Zylkene can help in many situations where animals might be expected to feel anxious or stressed. However do remember that you have a part to play too. Our animals have a phenomenal ability to pick up on signals we give them. Zylkene works best when combined with thoughtful and considerate handling from calm and sensible people!
Suitable for situations such as:
Changes in environment
Being left alone
New person, baby or pet being introduced
Travelling
Kennel or cattery visits
Fireworks
Loud noises and thunderstorms
Vet visits
Celebrations
Moving house
Lactation
Weaning
For oral administration.
The recommended daily amount should be given in one intake.
The capsule can be opened and the powder mixed with food or a treat.
| Zylkene 75mg for cats and small dogs | Up to 5kg | 1 capsule per day |
| Zylkene 75mg for cats and small dogs | 5-10 kg | 2 capsules per day |
| Zylkene 225mg for medium dogs | 10-15kg | 1 capsule per day |
| Zylkene 225mg for medium dogs | 15-30kg | 2 capsules per day |
| Zylkene 450mg for large dogs | 15-30kg | 1 capsule per day |
| Zylkene 450mg for large dogs | 30-60kg | 2 capsules per day |
Short Term Use: use for 1-2 days before the predicted event or change in environment. Some animals may need earlier administration (5-7 days).
Longer Term Use: 1-2 months
Horses up to 500kg: 1 sachet daily
Horses over 500kg: 2 sachets daily
Horses are often dosed for 2 days prior to a particular event, as well as on the day itself. Longer periods can be given, up to permanent, daily medication.
Powder 77.3%: Maltodextrin, Casein (Trypsin hydrolysis bovine casein), Magnesium stearate
Capsule 22.7%: Bovine skin gelatine
Powder 76.9%: Casein (Trypsin hydrolysis bovine casein), Maltodextrin, Magnesium stearate,
Capsule 23.1% Bovine Skin gelatine
Powder 82.9%: Casein (Trypsin hydrologic bovine casein), Magnesium Stearate
Capsule 17.1%: Bovine skin gelatine
Crude protein 39%, Crude ash 4%, Moisture 8%, Crude fat 2.5%, Crude fibre 0%
Crude protein 75%, Crude ash 10.5%, Moisture 8%, Crude fat 2%, Crude fibre 0%
Crude protein 78%, Crude ash 12%, Moisture 8%, Crude fat 3%, Crude fibre 0%
All prices include VAT where applicable.
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| Absence Of Side Effects |
Only verified purchasers of this product can leave a review.
Recommended by my vet. She is a very anxious cat and pedigree.
Customer recommends this product
Cat remained very stressed
Customer does not recommend this product
I was quite sceptical about these helping my anxious elderly Labrador but they saw him through firework season and are helping him to relax again at night after his return from hospital for pancreatitis treatment. If using for a particular stressful event, I would start dosing a few days before
Customer recommends this product
I think that this product did contribute in helping my dog feel calmer in the house while the fireworks were happening, I found that there was less panting and he was a bit more relaxed this time.
Customer recommends this product
Unfortunately this product had no calming effect on my dog Minnie.
Customer does not recommend this product
1 person found this review helpful
Below are some recent questions we've received regarding Zylkene, including answers from our team.
Yeo Won Park
Hello.
I want to know how many capsules in "pack of 100" are.
Thank you.
There are 100 capsules in a pack of 100. The strength of the capsules you need (75mg, 225mg or 450mg) is dependent on the weight of your dog or cat. Please see guide below:
The recommended daily amount should be given in one intake.
The capsule can be opened and the powder mixed with food or a treat.
| Zylkène 75mg for cats and small dogs | Up to 5kg | 1 capsule per day |
| Zylkène 75mg for cats and small dogs | 5-10 kg | 2 capsules per day |
| Zylkène 225mg for medium dogs | 10-15kg | 1 capsule per day |
| Zylkène 225mg for medium dogs | 15-30kg | 2 capsules per day |
| Zylkène 450mg for large dogs | 15-30kg | 1 capsule per day |
| Zylkène 450mg for large dogs | 30-60kg | 2 capsules per day |
Amanda
Can I give zylkene with Seren-um? Two of my five cats are not getting on and both have been so stressed they have been spraying in the house. I've been using Zylkene for a few days and things are better but still quite tense. I also wondered about the valerian spot on for some quick calm.
Thanks for your help
You can use Zylkene with Seren-um since they work in different ways however I would suggest using only one at a time since you won't know which one is having an effect if you use both together. I would actually try a Feliway Friends diffuser over the calmers though. It has been clinically proven to reduce conflict between housemate cats.
Sophie Matthews
what dosage would you recommend for a small terrier
I would guess that your dog weighs somewhere between 5-10kg in which case you would need to give 2 of the 75mg capsules per day.
Derek Thomson
37.5 Kilos large Greyhound what dosage does he require, he is not overly anxious but they do bother him?
The correct dose for your dog would be 2 large dog capsules a day. I would start them 2 days before the event- in this case I am presuming bonfire night! In particularly anxious dogs it is worth starting the capsules up to 7 days before the event but it sounds as though your dog will be fine starting 2 days before.
Susan Blanchflower
Would zylkene in your opinion help my main coons visit to the Cattery, he has been going to the same Cattery since he was young. The Cattery tells me he settles in OK but when it's time to go home he turns into a wild cat, spitting and growling and very aggressive, it takes him about a day to get back to his normal gentle personality.
I would have thought zylkene would be very helpful for your cat in this situation. It certainly won't do him any harm so is definitely worth a try next time he goes to the cattery.
Olivia Curry
Hi
I have a very anxious miniature schnauzer and was prescribed these by my vet, he has been taking a daily dose for a couple of days, how long does it take until they start to show?
Thank you
You should start to notice small changes after a few days but it could be a little longer before you really notice a difference. Zylkene is usually very helpful but if you find you do not got the complete effect you require seeking advice from an animal behaviourist alongside the zylkene is a good idea. You can also get some useful advice on apbc.org.uk
Dan Power
Dennis hates grooming and is struggling and biting at the groomers whilst getting cut. Can this product help as they are refusing to groom him in future if he isn't calmer.
Zylkene will help to calm Dennis if he is biting due to fear and being anxious at the groomers. It is certainly worth a try although it may be that you need stronger medication which we can usually supply but will need to be prescribed by your vet. It may also be worth a look at apbc.org.uk which gives some good advice on dog behaviour issues.
Sharon
What dosage would you give stressy horse when ridden. Angel in the stable. Weighs 480kg
For a horse under 500kg the amount is one sachet (of Zylkene Equine) per day. If you do this for a long time (over about 2 months) it will not be as effective, though it is perfectly safe. It can be done for a few days most effectively (to cover for a particular event etc).
Abbie Sol
I've used this product successfully a few times since last year's firework night. My dog goes through phases of being anxious and unsettled at night times, especially in weird weather. How long can I use this for? I want to support him to feel calm but I want to do what's best for his body too. He's well fed (natural food, no additives), trained and exercised. We've tried a dap diffuser and sedatives (firework night) with no success. I've started using zulkene this time to help him stay settled through the night, he's started digging in his crate. It's the same place he's slept for five years. He's always shown this behaviour during thunderstorms etc but it's become a nightly occurrence. He's a 7yr old staffy, we keep to a similar weekly routine.
Zylkene is a very safe product and is not going to cause any trouble even if you keep giving it all the time, but it would tend to have a diminishing affect if you were to do that. You can safely use it whenever the weather is "weird" or there are any unusual factors. You could try Aktivait or Senelife if your dog is particularly upset at night, They are safe supplements meant for older dogs but they can help in this situation. If your dog needs extra help for fireworks etc in future, then I would ask your vet about alprazolam, a human drug sold under the brand name Xanax. It is usually remarkably effective for "panic" situations in dogs, without causing and sedation (sedatives rarely work in fact).
Ursula
How many and what dosage per day to would I give a very anxious dog who weighs 6.2kg?
You should give 2 of the small (75mg) capsules daily, for as long as required.