TermaWorm™ Tablets for Cats & Dogs

TermaWorm Tablets for Cats and Kittens 230/20 mg

ACTIVE SUBSTANCE(S) )

Each film-coated tablet contains Pyrantel embonate 230 mg and Praziquantel 20 mg.

INDICATION(S)

For the treatment of mixed infections caused by the following gastrointestinal roundworms and tapeworms:

Roundworms: Toxocara cati, Toxascaris leonina,

Tapeworms: Dipylidium caninum, Taenia taeniaeformis, Echinococcus multilocularis.

DOSAGE AND METHOD OF ADMINISTRATION

Do not use in kittens less than 6 weeks of age.

The recommended dose is: 20 mg/kg pyrantel (57.5 mg/kg pyrantel embonate) and 5 mg/kg praziquantel. This is equivalent to 1 tablet per 4 kg bodyweight.

Administration and duration of treatment

Single oral administration. The tablet should be given directly to the cat, but if necessary can be disguised in food. Wash hands after use.

In ascarid infestation, especially in kittens, complete elimination cannot be expected, so a risk of infection for humans can persist. Repeat treatments should, therefore, be carried out with a suitable roundworm product at 14 day intervals until 2-3 weeks fter weaning.

To ensure administration of a correct dose, body weight should be determined as accurately as possible

SPECIAL WARNING(S)

Do not use during pregnancy but may be used during lactation.

After doses higher than 5 times the recommended dose, signs of intolerance such as vomiting have been observed.

Fleas serve as intermediate hosts for one common type of tapeworm – Dipylidium caninum. Tapeworm infestation is certain to reoccur unless control of intermediate hosts such as fleas, mice, etc. is undertaken.

NFA-VPS

TermaWorm Tablets for Dogs 50/50/150 mg

ACTIVE SUBSTANCE(S)

Pale yellow pork-flavoured tablets with a cross breakline on one side . Each tablet contains Praziquantel 50 mg, Pyrantel 50 mg (equivalent to 144 mg Pyrantel Embonate) and Febantel 150 mg. The tablets can be divided into halves or quarters.

INDICATION(S)

In dogs: Treatment of mixed infections by nematodes and cestodes of the following species

Nematodes:

Ascarids: Toxocara canis, Toxascaris leonina (adult and late immature forms).

Hookworms: Uncinaria stenocephala, Ancylostoma caninum (adults).

Whipworms: Trichuris vulpis (adults).

Cestodes:

Tapeworms: Echinococcus species, (E. granulosus, E. multilocularis), Taenia species,

(T. hydatigena, T. pisiformis, T. taeniformis) Dipylidium caninum (adult and immature forms).

DOSAGE AND METHOD OF ADMINISTRATION

Single dose: For oral administration.

The recommended dose rates are: 15 mg/kg bodyweight febantel, 5 mg/kg pyrantel (equivalent to 14.4 mg/kg pyrantel embonate) and 5 mg/kg praziquantel.

1 tablet per 10 kg (22 lbs) bodyweight. The tablets can be given directly to the dog or disguised in food. No starvation is needed before, or after, treatment.

The tablet can be divided in two or four equal doses.

Dosage table:

The advice of a veterinarian should be sought regarding the need for and the frequency of repeat administration.

To ensure administration of a correct dose, bodyweight should be determined as accurately as possible.

ADVERSE REACTIONS

In very rare cases slight and transient digestive tract disorders such as vomiting and /or diarrhoea may occur.
In individual cases these signs can be accompanied by nonspecific signs such as lethargy, anorexia or hyperactivity.

The frequency of adverse reactions is defined using the following convention:
- Very common (more than 1 in 10 animals treated displaying adverse reaction(s)).
- Common (more than 1 but less than 10 animals in 100 animals treated).
- Uncommon (more than 1 but less than 10 animals in 1,000 animals treated).
- Rare (more than 1 but less than 10 animals in 10,000 animals treated).
- Very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

SPECIAL WARNING(S)

Do not use simultaneously with piperazine compounds as the anthelmintic effects of pyrantel and piperazine may be antagonized.

Concurrent use with other cholinergic compounds (e.g.foxim) can lead to toxicity.

If you are uncertain, and your dog uses other veterinary medicinal products,check with a veterinary surgeon or pharmacist.

Fleas serve as intermediate hosts for one common type of tapeworm – Dipylidium caninum.

Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.

Tapeworm infestation is unlikely in pups less than 6 weeks of age.

Teratogenic effects attributed to high doses of febantel have been reported in sheep and rats. No studies have been performed in dogs during early pregnancy. Use of the product during pregnancy should be in accordance with a benefit risk assessment by the responsible veterinarian. It is recommended that the product is not used in dogs during the first 4 weeks of pregnancy. Do not exceed the stated dose when treating pregnant bitches.

Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.

Overdose:

The combination of praziquantel, pyrantel embonate and febantel is well tolerated in dogs. In safety studies, a single dose of 5 times the recommended dose or greater gave rise to occasional vomiting.

NFA-VPS

TermaWorm XL Tablets for Dogs 175 mg Praziquantel /175 mg Pyrantel /525 mg Febantel

ACTIVE SUBSTANCES

Each pork flavoured tablet contains 175 mg Praziquantel, 175 mg Pyrantel (equivalent to 504 mg Pyrantel Embonate) and 525 mg Febantel. The tablets can be divided into halves.

INDICATION(S)

In adult dogs: Treatment of mixed infections by nematodes and cestodes of the following species

Nematodes:

Ascarids: Toxocara canis, Toxascaris leonina (adult and late immature forms).

Hookworms: Uncinaria stenocephala, Ancylostoma caninum (adults).

Whipworms: Trichuris vulpis (adults).

Cestodes:

Tapeworms: Echinococcus species, (E. granulosus, E. multilocularis), Taenia species,

(T. hydatigena, T. pisiformis, T. taeniformis) Dipylidium caninum (adult and immature forms).

DOSAGE AND METHOD OF ADMINISTRATION

The tablets can be given directly to the dog or disguised in food. No starvation is needed before or after treatment. Wash hands after use.

The recommended dose rates are: 15mg/kg bodyweight febantel, 5 mg/kg pyrantel (equivalent to 14.4 mg/kg pyrantel embonate) and 5 mg/kg praziquantel. This is equivalent to 1 TermaWorm XL Tablets for Dogs per 35 kg bodyweight.

Dogs of > 35 kg bodyweight should be given 1 TermaWorm XL Tablets for Dogs plus the appropriate quantity of TermaWorm Tablets for Dogs equivalent to 1 tablet per 10 kg bodyweight.

Dogs weighing approx 17.5kg bodyweight should be given ½ TermaWorm XL tablet.

Dosage table:

If there is a risk for re-infestation, the advice of a veterinarian should be sought regarding the need for and the frequency of repeat administration.

To ensure administration of a correct dose, body weight should be determined as accurately as possible

Unused half tablet must be used within 14 days.

ADVERSE REACTIONS

Slight and transient digestive tract disorders such as vomiting and /or diarrhoea may occur in very rare cases.
Non-specific signs such as lethargy, anorexia or hyperactivity can accompany these signs in individual cases.

The frequency of adverse reactions is defined using the following convention:
- Very common (more than 1 in 10 animals treated displaying adverse reaction(s)).
- Common (more than 1 but less than 10 animals in 100 animals treated).
- Uncommon (more than 1 but less than 10 animals in 1,000 animals treated).
- Rare (more than 1 but less than 10 animals in 10,000 animals treated).
- Very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
If you notice any side effects, even those not already listed in this package leaflet, or you think that the medicine has not worked, please inform your veterinary surgeon.

SPECIAL WARNING(S)

Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class. Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.

Special precautions for use in animals:

To ensure administration of a correct dose, body weight should be determined as accurately as possible.

Interaction with other medicinal products and other forms of interaction:

Do not use simultaneously with piperazine compounds as the anthelmintic effects of pyrantel and piperazine may be antagonized. Concurrent use with other cholinergic compounds can lead to toxicity. Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.

Pregnancy:

Teratogenic effects attributed to high doses of febantel have been reported in sheep and rats. No studies have been performed in dogs during early pregnancy. Use of the product during pregnancy should be in accordance with a benefit risk assessment by the responsible veterinarian. It is recommended that the product is not used in dogs during the first 4 weeks of pregnancy. Do not exceed the stated dose when treating pregnant bitches.

Overdose (symptoms, emergency procedures, antidotes):

In safety studies, a single dose of 5 times the recommended dose or greater gave rise to occasional vomiting.