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Synulox Antibiotic for Dogs & Cats

Synulox Antibiotic for Dogs & Cats
LC Syringes » Pack of 12
Palatable Drops » 15ml

  • 50mg Tablets » Priced per Tablet £0.49
  • 250mg Tablets » Priced per Tablet £0.89
  • 500mg Tablets » Priced per Tablet £1.69
  • LC Syringes » Pack of 12 £28.49
  • LC Syringes » Pack of 24 £54.49
  • Palatable Drops » 15ml £11.99

Selection of 6 products from

£0.49 to £54.49

Description

Synulox is the most commonly used antibiotic for dogs and cats in the UK. It contains amoxycillin and clavulanic acid which act together to provide a safe and effective antibiotic with activity against a wide range of bacteria. The tablets are flavoured to ease administration to dogs and cats and are given twice daily. They will normally be eaten from the hand, or can be crumbled and added to food. Synulox is safe to use during pregnancy and lactation in dogs and cats. Smaller animals can be given Synulox Drops, but they are not suitable for small herbivores such as rabbits and guinea pigs, which can develop serious enteritis following the use of this type of antibiotic.
Synulox LC is supplied in single-use syringes to treat mastitis in milking cows.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

250mg Tablets » Priced per Tablet

Synulox Palatable Tablets 50 mg and 250 mg

Presentation

Synulox Palatable Tablets are presented as circular, pink tablets with a break line on one face and `SYNULOX' engraved on the other. Each tablet contains clavulanic acid as potassium clavulanate and amoxicillin as Amoxicillin trihydrate in a palatable base. The composition of the two tablet sizes is as follows:

50 mg

40 mg amoxicillin and 10 mg clavulanic acid.

250 mg

200 mg amoxicillin and 50 mg clavulanic acid.

Uses

Synulox Palatable Tablets have a notably broad spectrum of bactericidal activity against bacteria commonly found in cats and dogs.

In vitro Synulox is active against a wide range of clinically important aerobic and anaerobic bacteria including:

Gram-positive: Staphylococci (including β-lactamase producing strains); Clostridia; Corynebacteria; Peptostreptococcus spp; Streptococci.
Gram-negative: Bacteroides spp (including β-lactamase producing strains); Escherichia coli (including most β-lactamase producing strains); Salmonellae (including β-lactamase producing strains); Bordetella bronchiseptica; Campylobacter spp; Fusobacterium necrophorum; Klebsiellae; Pasteurellae; Proteus spp.

Clinically Synulox has been shown to be effective in treating a wide range of diseases of cats and dogs including: Skin disease (including deep and superficial pyodermas); soft tissue infections (abscesses and anal sacculitis); dental infections (eg gingivitis); urinary tract infections; respiratory disease (involving upper and lower respiratory tract); enteritis.

Dosage and administration

Administration

By the oral route. Synulox palatable tablets are often accepted from the hand even by sick cats and dogs. Alternatively, the tablets may be crushed and added to a little food.

Dosage rate

12.5 mg/kg bodyweight.

Dosage frequency

The following table is intended as a guide to dispensing Synulox Palatable Tablets at the standard dose rate of 12.5 mg/kg, twice daily.

For the majority of infections, including those of the skin, urinary tract and gastrointestinal tract, the above dosing regime is effective.

Refractory cases, however, particularly those of the respiratory tract, have shown improved cure rates by doubling the dose to 25 mg/kg bodyweight twice daily. (Note that the smallest animals of 1 kg bodyweight when dosed with ½ tablet will already be receiving the doubled (25 mg/kg) dose rate.)

Duration of therapy

Routine cases involving all indications: The majority of these cases respond to between 5 and 7 days therapy.

Chronic or refractory cases

In these cases, where there is considerable tissue damage, a longer course of therapy may be required in that it allows sufficient time for damaged tissue to repair. Based on clinical trials, the following durations are suggested as guidelines:

Chronic skin disease 10–20 days
Chronic cystitis 10–28 days
Respiratory disease 8–10 days

Contra-indications, warnings, etc

For animal treatment only. Synulox Palatable Tablets should not be given to rabbits, guinea pigs, hamsters or gerbils. Caution is advised in their use in any other very small herbivores.

Operator warning

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reaction to cephalosporins and vice-versa. Allergic reaction to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Wash hands after use.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms, and may require urgent medical attention.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Keep out of the sight and reach of children.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

Packaging quantities

Both size tablets are packed in foil strips containing 5 x 2 tablets. 50 mg tablets are supplied in packs of 100 and 500, 250 mg tablets are in packs of 100 and 250. Not all pack sizes may be marketed.

Further information

Resistance to many antibiotics is caused by beta-lactamase enzymes which destroy the antibiotic before it can act on the bacteria themselves. The clavulanate in Synulox counteracts this defence mechanism by inactivating the beta-lactamases, thus rendering the organisms sensitive to amoxicillin's rapid bactericidal effect, at concentrations readily attainable in the body.

Synulox is effective against Klebsiella infections found in veterinary practice, but it is not indicated for cases involving Pseudomonas species.

Synulox Palatable Tablets are often accepted from the hand, even by sick dogs and cats. Alternatively, the tablets may be crumbled and added to a little food.

Synulox Palatable Tablets can safely be used during pregnancy and lactation.

Synulox Palatable Drops are available as an alternative presentation for treating small individuals.

Marketing Authorisation Number

50 mg Vm 42058/4147
250 mg Vm 42058/4145

50mg Tablets » Priced per Tablet

Synulox Palatable Tablets 50 mg and 250 mg

Presentation

Synulox Palatable Tablets are presented as circular, pink tablets with a break line on one face and `SYNULOX' engraved on the other. Each tablet contains clavulanic acid as potassium clavulanate and amoxicillin as Amoxicillin trihydrate in a palatable base. The composition of the two tablet sizes is as follows:

50 mg

40 mg amoxicillin and 10 mg clavulanic acid.

250 mg

200 mg amoxicillin and 50 mg clavulanic acid.

Uses

Synulox Palatable Tablets have a notably broad spectrum of bactericidal activity against bacteria commonly found in cats and dogs.

In vitro Synulox is active against a wide range of clinically important aerobic and anaerobic bacteria including:

Gram-positive: Staphylococci (including β-lactamase producing strains); Clostridia; Corynebacteria; Peptostreptococcus spp; Streptococci.
Gram-negative: Bacteroides spp (including β-lactamase producing strains); Escherichia coli (including most β-lactamase producing strains); Salmonellae (including β-lactamase producing strains); Bordetella bronchiseptica; Campylobacter spp; Fusobacterium necrophorum; Klebsiellae; Pasteurellae; Proteus spp.

Clinically Synulox has been shown to be effective in treating a wide range of diseases of cats and dogs including: Skin disease (including deep and superficial pyodermas); soft tissue infections (abscesses and anal sacculitis); dental infections (eg gingivitis); urinary tract infections; respiratory disease (involving upper and lower respiratory tract); enteritis.

Dosage and administration

Administration

By the oral route. Synulox palatable tablets are often accepted from the hand even by sick cats and dogs. Alternatively, the tablets may be crushed and added to a little food.

Dosage rate

12.5 mg/kg bodyweight.

Dosage frequency

The following table is intended as a guide to dispensing Synulox Palatable Tablets at the standard dose rate of 12.5 mg/kg, twice daily.

For the majority of infections, including those of the skin, urinary tract and gastrointestinal tract, the above dosing regime is effective.

Refractory cases, however, particularly those of the respiratory tract, have shown improved cure rates by doubling the dose to 25 mg/kg bodyweight twice daily. (Note that the smallest animals of 1 kg bodyweight when dosed with ½ tablet will already be receiving the doubled (25 mg/kg) dose rate.)

Duration of therapy

Routine cases involving all indications: The majority of these cases respond to between 5 and 7 days therapy.

Chronic or refractory cases

In these cases, where there is considerable tissue damage, a longer course of therapy may be required in that it allows sufficient time for damaged tissue to repair. Based on clinical trials, the following durations are suggested as guidelines:

Chronic skin disease 10–20 days
Chronic cystitis 10–28 days
Respiratory disease 8–10 days

Contra-indications, warnings, etc

For animal treatment only. Synulox Palatable Tablets should not be given to rabbits, guinea pigs, hamsters or gerbils. Caution is advised in their use in any other very small herbivores.

Operator warning

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reaction to cephalosporins and vice-versa. Allergic reaction to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Wash hands after use.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms, and may require urgent medical attention.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Keep out of the sight and reach of children.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

Packaging quantities

Both size tablets are packed in foil strips containing 5 x 2 tablets. 50 mg tablets are supplied in packs of 100 and 500, 250 mg tablets are in packs of 100 and 250. Not all pack sizes may be marketed.

Further information

Resistance to many antibiotics is caused by beta-lactamase enzymes which destroy the antibiotic before it can act on the bacteria themselves. The clavulanate in Synulox counteracts this defence mechanism by inactivating the beta-lactamases, thus rendering the organisms sensitive to amoxicillin's rapid bactericidal effect, at concentrations readily attainable in the body.

Synulox is effective against Klebsiella infections found in veterinary practice, but it is not indicated for cases involving Pseudomonas species.

Synulox Palatable Tablets are often accepted from the hand, even by sick dogs and cats. Alternatively, the tablets may be crumbled and added to a little food.

Synulox Palatable Tablets can safely be used during pregnancy and lactation.

Synulox Palatable Drops are available as an alternative presentation for treating small individuals.

Marketing Authorisation Number

50 mg Vm 42058/4147
250 mg Vm 42058/4145

500mg Tablets » Priced per Tablet

Synulox Palatable Tablets 500 mg

Presentation

Synulox Palatable Tablets are presented as circular, pink tablets with a break line on one face and `SYNULOX' engraved on the other. Each tablet contains 100 mg clavulanic acid as potassium clavulanate and 400 mg amoxicillin as Amoxicillin trihydrate in a palatable base.

Uses

Synulox Palatable Tablets have a broad spectrum of activity against bacteria commonly found in dogs.

In vitro Synulox is active against a wide range of clinically important aerobic and anaerobic bacteria, including:

Gram-positive Staphylococci (including beta-lactamase-producing strains), Clostridia, Actinomyces, Peptostreptococcus spp., Streptococci, Enterococci
Gram-negative Bacteroides spp. (including β-lactamase-producing strains), Escherichia coli (including beta-lactamase-producing strains), Salmonellae (including β-lactamase-producing strains), Bordetella bronchiseptica, Campylobacter spp., Fusobacterium necrophorum, Klebsiellae, Pasteurellae, Proteus spp.

Clinically, Synulox has been shown to be effective in treating a wide range of diseases of dogs including: Skin disease (including deep and superficial pyoderma); urinary tract infection; respiratory disease involving upper and lower respiratory tract, enteritis, dental infections (e.g. gingivitis), soft tissue infections (e.g. abscesses and anal sacculitis).

Note: Synulox is not indicated for cases involving Pseudomonas spp.

Dosage and administration

Administration

By the oral route.

Dosage Guide

Recommended dose rate is 12.5 mg/kg, twice daily. The table below is intended as a guide only.

For oral administration only. Synulox Palatable Tablets are often accepted from the hand, even by sick dogs. Alternatively, the tablets may be crushed and added to a small quantity of food. The majority of routine cases will respond between 5 and 7 days therapy. Because of the low toxicity profile of Synulox, the dose can be doubled if desired at the discretion of the veterinary surgeon for severe infection. In certain indications, for example canine pyoderma and chronic cystitis, bacterial infection may be secondary to other pathology. For such cases longer courses of antibacterial therapy may be required, in addition to diagnosis and treatment of the underlying condition. In such circumstances overall treatment length must be at the clinician's discretion, but should be long enough to ensure complete resolution of the bacterial disease.

Contra-indications, warnings, etc

In common with other penicillins, Synulox should not be administered orally to rabbits, guinea pigs hamsters or gerbils, and should be used with care in other small herbivores.

Synulox should not be administered concomitantly with bacteriostatic antibiotics, which are incompatible.

Operator warning

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reaction to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and may require urgent medical attention.

In the event of accidental ingestion, seek medical advice.

Wash hands after handling the tablets.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Keep out of the sight and reach of children.

For animal treatment only.

Legal category

Packaging quantities

Laminated aluminium foil packs with 2 tablets in each blister card. Packed in an outer carton box and marketed as a 100 tablet presentation.

Further information

Amoxicillin is a broad-spectrum antibiotic active against a wide range of Gram-positive and Gram-negative bacteria. However, many clinically important bacteria produce beta-lactamase enzymes which destroy this antibiotic. Clavulanic acid inactivates these enzymes, rendering the organisms susceptible to the amoxicillin.

Synulox Palatable Tablets can safely be used in pregnant and lactating animals

Marketing Authorisation Number

Vm 42058/4146

Palatable Drops » 15ml

Synulox Palatable Drops, Powder for Oral Suspension

Presentation

Synulox Palatable Drops are presented in a bottle as an off-white powder, containing 150 mg potassium clavulanate equivalent to clavulanic acid and 600 mg Amoxicillin trihydrate equivalent to amoxicillin. Reconstitution of the powder with 15 ml of water provides a suspension containing 10 mg clavulanic acid and 40 mg amoxicillin per ml.

Uses

Synulox Palatable Drops have a notably broad spectrum of bactericidal activity against bacteria commonly found in dogs and cats.

In vitro Synulox is active against a wide range of clinically important aerobic and anaerobic bacteria including:

Gram-positive: Staphylococci (including β-lactamase producing strains); Clostridia; Corynebacteria; Peptostreptococcus spp; Streptococci
Gram-negative: Bacteroides spp. (including β-lactamase producing strains); Escherichia coli (including most β-lactamase producing strains); Salmonellae (including β-lactamase producing strains); Bordetella bronchiseptica; Campylobacter spp; Fusobacterium necrophorum; Klebsiellae; Pasteurellae; Proteus spp.

Clinically Synulox has been shown to be effective in treating a wide range of diseases of cats and dogs including: Skin disease (including deep and superficial pyodermas); soft tissue infections (abscesses and anal sacculitis); dental infections (eg gingivitis); urinary tract infections; respiratory disease (involving upper and lower respiratory tract); enteritis.

Dosage and administration

Administration

By the oral route.

Reconstitution

Add 15 ml water. Shake the bottle before use.

Dosage rate

12.5 mg/kg bodyweight (i.e. 0.25 ml/kg). For the accurate dosing of particularly small patients it is valuable to note that one drop from the pipette provided contains 2.3 mg clavulanate-potentiated amoxicillin. Therefore 5–6 drops/kg twice daily are recommended as a guide.

Dosage frequency

Dogs and cats should be dosed at the rate of 0.25 ml of reconstituted product per kg bodyweight twice daily.

For the majority of infections, including those of the skin, urinary tract and gastrointestinal tract, the above dosing regime is effective.

Refractory cases, however, particularly those of the respiratory tract, have shown improved cure rates by doubling the dose to 25 mg/kg bodyweight twice daily (i.e. 0.5 ml of reconstituted product per kg bodyweight twice daily).

Duration of therapy

Routine cases involving all indications

The majority of these cases respond to between 5 and 7 days therapy.

Chronic or refractory cases

In these cases, where there is considerable tissue damage, a longer course of therapy may be required in that it allows sufficient time for damaged tissue to repair. Based on clinical trials, the following durations are suggested as guidelines:

Chronic skin disease 10–20 days
Chronic cystitis 10–28 days
Respiratory disease 8–10 days

Contra-indications, warnings, etc

Synulox Palatable Drops should not be given to rabbits, guinea pigs, hamsters or gerbils. Caution is advised in their use in any other very small herbivores.

Operator warning

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice-versa. Allergic reaction to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure, such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and may require urgent medical attention.

Wash hands after use.

Pharmaceutical precautions

Powder: Do not store above 25°C.

Reconstituted suspension: Store at 2-8°C. Any reconstituted suspension remaining 7 days after preparation should be discarded.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Keep out of the sight and reach of children.

For animal treatment only.

Legal category

Packaging quantities

Synulox Palatable Drops are supplied in bottles containing 15ml of product following reconstitution (equivalent to 750 mg of clavulanate-potentiated amoxicillin). A dropper with graduations of 0.25 ml, up to 1 ml, is included in each pack to ensure accurate, convenient dosing.

Further information

Resistance to many antibiotics is caused by beta-lactamase enzymes which destroy the antibiotic before it can act on the bacteria themselves. The clavulanate in Synulox counteracts this defence mechanism by inactivating the beta-lactamases, thus rendering the organisms sensitive to amoxicillin's rapid bactericidal effect, at concentrations readily attainable in the body.

Synulox is effective against Klebsiella infections found in veterinary practice, but it is not indicated for cases involving Pseudomonas species.

Synulox Palatable Drops can be safely used in pregnant and lactating animals.

Synulox Palatable Tablets are available as an alternative presentation for treating sick dogs and cats.

Marketing Authorisation Number

Vm 42058/4144

LC Syringes » Pack of 12

Synulox Lactating Cow Intramammary Suspension

Presentation

Synulox Lactating Cow is an intramammary suspension, each 3 g syringe containing 200 mg amoxicillin (as amoxicillin trihydrate), 50 mg clavulanic acid (as potassium clavulanate) and 10 mg prednisolone.

Uses

For use in clinical cases of mastitis in lactating cattle including cases associated with infections with the following pathogens:

Staphylococci (including β-lactamase producing strains),

Streptococci (including S. agalactiae, S. dysgalactiae, and S. uberis),

Escherichia coli (including β-lactamase-producing strains).

Dosage and administration

Before the infusion is made, the teat end should be cleaned and disinfected.

The contents of one syringe should be infused into each affected quarter via the teat canal, immediately after milking, at 12 hour intervals for three consecutive milkings.

In cases of infections caused by Staphylococcus aureus, a longer course of antibacterial therapy may be required. Therefore, overall treatment length must be at the veterinary surgeon’s discretion but should be long enough to ensure complete resolution of the intramammary infection.

Contra-indications, warnings, etc

Do not use in animals which are known to be hypersensitive to β-lactamase antibiotics.

Do not use in cases associated with Pseudomonas.

Synulox Lactating Cow should be used for treatment of clinical mastitis only.

Swab teat end with an appropriate disinfectant before treatment.

Use of the product should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria and take into account official and local antimicrobial policies.

The use of the product should preferably be based on susceptibility tests.

Avoid use of the product in herds where no β-lactamase producing Staphylococci strains have been isolated. Veterinarians should strive to use narrow spectrum antibiotics if possible. Inappropriate use of the product may increase the prevalence of bacteria resistant to β-lactam antibiotics and may decrease the effectiveness of treatment with β-lactam antibiotics, due to the potential for cross-resistance.

Withdrawal periods

Meat and offal: 7 days.

Milk: 84 hours, i.e. 7 milkings with 2 times a day milking or 11 milkings with 3 times a day milking.

Operator warnings

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention.

Wash hands after use.

Pharmaceutical precautions

Store in a dry place. Do not store above 25°C.

Keep out of the sight and reach of children. For animal treatment only.

Any unused veterinary medicinal product or waste materials from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

Cartons of 12 and 24 syringes. Not all pack sizes may be marketed.

Further information

Amoxicillin is a broad spectrum bactericidal b-lactam antibiotic. Clavulanic acid inactivates b-lactamases. This combination is effective against b-lactamase producing organisms. Prednisolone is an anti-inflammatory corticosteroid.

In vitro, clavulanic acid and amoxicillin in combination are active against a wide range of clinically important bacteria including the following organisms which are commonly associated with bovine mastitis:

Staphylococci (including b-lactamase producing strains)

Streptococci (including S. agalactiae, S. dysgalactiae and S. uberis)

Arcanobacteria (including A. pyogenes)

Escherichia coli (including β-lactamase producing strains)

No adverse reactions are to be expected from an accidental overdose.

Marketing Authorisation Number

Vm 42058/4143

LC Syringes » Pack of 24

Synulox Lactating Cow Intramammary Suspension

Presentation

Synulox Lactating Cow is an intramammary suspension, each 3 g syringe containing 200 mg amoxicillin (as amoxicillin trihydrate), 50 mg clavulanic acid (as potassium clavulanate) and 10 mg prednisolone.

Uses

For use in clinical cases of mastitis in lactating cattle including cases associated with infections with the following pathogens:

Staphylococci (including β-lactamase producing strains),

Streptococci (including S. agalactiae, S. dysgalactiae, and S. uberis),

Escherichia coli (including β-lactamase-producing strains).

Dosage and administration

Before the infusion is made, the teat end should be cleaned and disinfected.

The contents of one syringe should be infused into each affected quarter via the teat canal, immediately after milking, at 12 hour intervals for three consecutive milkings.

In cases of infections caused by Staphylococcus aureus, a longer course of antibacterial therapy may be required. Therefore, overall treatment length must be at the veterinary surgeon’s discretion but should be long enough to ensure complete resolution of the intramammary infection.

Contra-indications, warnings, etc

Do not use in animals which are known to be hypersensitive to β-lactamase antibiotics.

Do not use in cases associated with Pseudomonas.

Synulox Lactating Cow should be used for treatment of clinical mastitis only.

Swab teat end with an appropriate disinfectant before treatment.

Use of the product should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria and take into account official and local antimicrobial policies.

The use of the product should preferably be based on susceptibility tests.

Avoid use of the product in herds where no β-lactamase producing Staphylococci strains have been isolated. Veterinarians should strive to use narrow spectrum antibiotics if possible. Inappropriate use of the product may increase the prevalence of bacteria resistant to β-lactam antibiotics and may decrease the effectiveness of treatment with β-lactam antibiotics, due to the potential for cross-resistance.

Withdrawal periods

Meat and offal: 7 days.

Milk: 84 hours, i.e. 7 milkings with 2 times a day milking or 11 milkings with 3 times a day milking.

Operator warnings

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention.

Wash hands after use.

Pharmaceutical precautions

Store in a dry place. Do not store above 25°C.

Keep out of the sight and reach of children. For animal treatment only.

Any unused veterinary medicinal product or waste materials from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

Cartons of 12 and 24 syringes. Not all pack sizes may be marketed.

Further information

Amoxicillin is a broad spectrum bactericidal b-lactam antibiotic. Clavulanic acid inactivates b-lactamases. This combination is effective against b-lactamase producing organisms. Prednisolone is an anti-inflammatory corticosteroid.

In vitro, clavulanic acid and amoxicillin in combination are active against a wide range of clinically important bacteria including the following organisms which are commonly associated with bovine mastitis:

Staphylococci (including b-lactamase producing strains)

Streptococci (including S. agalactiae, S. dysgalactiae and S. uberis)

Arcanobacteria (including A. pyogenes)

Escherichia coli (including β-lactamase producing strains)

No adverse reactions are to be expected from an accidental overdose.

Marketing Authorisation Number

Vm 42058/4143

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (10)

Q & A

Below are some recent questions we've received regarding Synulox Antibiotic for Dogs & Cats, including answers from our team.

16 March 2018 at 8:33am

Obsorb Synulox

Helen McLeod

How long does Synulox taken to obsorb in my dogs system, as she is being sick but managing to keep food down for a few hours which include this antibiotic.

  • Veterinary Advisor

Synulox should be absorbed within an hour so vomiting 2 hours after giving the tablet should not affect the efficacy of the antibiotic.

20 April 2016 at 9:55am

Crystals in cats

Carol M

Does Synalox help with reducing problems with crystals in cat

  • Non-Executive Director

In a way it might help indirectly. Synulox is an antibiotic so it kills bacteria in the bladder and helps to eliminate infection. There can be a complex relationship between infection in the bladder and the conditions which encourage crystals to form in the urine, with one encouraging the other. Synulox can certainly help with the overall situation and is often used as part of the treatment, but a change in diet and water intake is also important. (Personally I would always stop all dried food and give wet food only. That includes the prescription diets - dried diets are at best a compromise in treatment, whatever the manufacturer might say. Often these cats are overweight, so a reduction in the total amount of food consumed is also beneficial for them.)

13 September 2015 at 11:48am

How fast until it works

Jed

Hi,
My dogs have kennel cough and I'm using synulox, they've been on it 3 days and no improvement so far. How long should it take to clear them up?

  • Non-Executive Director

A lot of different infections are grouped together under the name "Kennel Cough" and in fact many individual cases will involve more than one type of infectious organism. This means that there is a lot of variation and some outbreaks seem to respond well to Synulox whereas some shoe very little response to any type of antibiotic. Many vets do not even prescribe antibiotics for routine cases of kennel cough. Sometimes anti-inflammatories are given to ease any discomfort/distress from the coughing, but often the infection has to run its course just as when you get a bad cold. Viruses often play a part in Kennel Cough and it is the body's immune system which deals with those, Synulox will make no difference.

The usual approach is to do what is needed to help things along, but essentially wait for the dogs' immune systems to deal with the infection. If you are concerned that they are not doing well, it is best to go back to your vet and see if anything more needs to be done.

13 August 2015 at 8:15am

Question of method of administration

Alex Mar

When to take medicine :
Before or after eating and drinking water?
How long ago or how long after eating and drinking water?
It repeated after vomiting and to what period? For example - if vomiting one hour after dosing, is it necessary repetition and in what dose?
(Excuse the mistakes - is used Google translation)

  • Non-Executive Director

Synulox is absorbed very well and so it is not important if food is present or not. You can give before food, with food or without food. It is not important. Normally if the patient vomits very soon after taking a dose I would recommend repeating the dose (it is very safe to give a double dose in fact). However if vomiting occurs more than one hour after taking the tablet, I would presume the drug has been absorbed and the vomiting is not important.

25 July 2014 at 1:48pm

Swollen leg due to a wound

roxey

Hi my dog recently cut her leg I've been bathing it but this morning the paw looks a little inflamed it's not a big wound but I'm wondering if synulox would be good for this thank you

  • Non-Executive Director

Synukox and all other antibiotics are prescription only in the UK so you can only buy some from us if you send us a prescription from your vet. This is because a vet should decide upon examining your dog whether or not antibiotics are appropriate. Very often they are not required, but sometimes they can be very important. Your vet is best able to assess this, much as we would like to help.

9 July 2014 at 8:01pm

My tomcat has been taking prescribed synulox 50 mg twice a day and since the first pill..

Ana-Maria

My tomcat is eating scarcely since the first pill.. I am asking if the drug synulox has as a side-effect the lack/diminishing of appetite. Thank you!

  • Non-Executive Director

Loss of appetite is not normally a side effect of Synulox. I think it is much more likely that an underlying illness is the cause. It would be best to get him checked again with your own vet.

8 October 2013 at 5:33pm

Prescription

c mcintosh

do isitsmy dog need a presciption he is prone to anal absesses and has one at present l have a few tablet left from previous vet v

  • Non-Executive Director

Sorry but we cannot sell this product without a prescription, whatever the situation.