Semintra Oral Solution for Cats

Semintra Oral Solution for Cats
4mg/ml » 30ml Bottle
4mg/ml » 100ml Bottle
10mg/ml » 35ml Bottle

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  • 4mg/ml » 30ml Bottle £29.68
  • 4mg/ml » 100ml Bottle £84.99
  • 10mg/ml » 35ml Bottle £76.24

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Semintra is a new drug developed to help cats which have reduced kidney function. It is very common for the kidneys in cats to deteriorate with age. (Our pet cats probably live much longer than cats in the wild would have done.) Hence a very large proportion of older cats (more than one third) do have less than perfect kidneys and could benefit from taking Semintra. It comes in liquid form and is palatable even to fussy cats, with 90% of cats eating it readily when tests have been conducted. Semintra has been shown to reduce the leakage of proteins in the urine, which helps maintain body weight and muscle mass in affected cats.

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Medication Datasheets

Reviews (27)

Summary of Reviews for Semintra Oral Solution for Cats

Overall 5
Ease Of Use
Value For Money
Absence Of Side Effects
27 out of 27 (100%) customers would recommend this product.
5 stars (24 reviews)
4 stars (3 reviews)
3 stars (0 reviews)
2 stars (0 reviews)
1 stars (0 reviews)

Only verified purchasers of this product can leave a review.

55 Vets recomendation
Verified Purchase

By on 3 May 2021


Customer recommends this product

55 Excellent!
Verified Purchase

By on 12 August 2019

My cat Jessye has no problem having this medicine in her food and it has brought her back from the brink brilliantly. Hopefully she will be around a lot longer thanks to Semintra.

Customer recommends this product

55 Elixir for Feline CRF
Verified Purchase

By on 17 June 2019

Semintra has brought down my 17y.o cat's vital kidney readings down to manageable levels albeit still on the high side. If only I had this earlier for my previous two elderly cats.

Only criticism is that VioVet's pricing for Semintra seems excessively high compared to other online Vets. Some 30% higher.

However, their communications platform and its delivery process are fantastic as notifies you at every step.

Customer recommends this product

55 My cats meds.
Verified Purchase

By on 16 May 2019

As it's a prescription med for my cats. So it is a great help.

Customer recommends this product

45 Very affordable
Verified Purchase

By on 20 November 2018

Very affordable

Customer recommends this product

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Q & A

Below are some recent questions we've received regarding Semintra Oral Solution for Cats, including answers from our team.

6 August 2020 at 3:24pm

Taken for how long?

jessica m sacret

My cat has been diagnosed with kidney disease and has been prescribed simintra, 0.75 ml per day. Does she need to take it daily for the rest of her life?

  • VioVet Staff

Semintra helps reduce the loss of protein through your cats urine. If the kidneys are damaged enough to need the medication then unfortunately your cat will likely need it for the rest of their life. The kidneys do not have a capacity to repair and any current damage is managed using treatment/diet as suggested by your vet.

27 October 2017 at 1:25pm


Tarmina Febriana

  • VioVet customer since 2010
  • From: Berkshire, United Kingdom

is it prescription only ?

  • VioVet Staff

Hello Tarmina, thank you for your question,

I can confirm that Semintra is a prescription only medication, so we would need to obtain a prescription before dispensing this product.

12 November 2016 at 1:39pm

Does Semintrea slow progression of CKD


  • VioVet customer since 2016
  • From: Surrey, United Kingdom

Is the effect of Semintrea just to reduce urine protien? Does it slow progression of the CKD? Our 16 year old cat has a urine protein of 0.10 g/l and a urine prot/creatinine ratio of 0.25 which the test results classify as borderline-proteinuric. Would semintrea benefit her? She also has hyperthyroidism (79 nmol/l thyroxin) which is being treated with Vidalta (just started). She has no outward symptoms apart from some weight loss.

  • VioVet Staff

The active substance in Semintra, telmisartan, is an ‘angiotensin II receptor antagonist’, which means that it blocks the action of a hormone in the body called angiotensin II. Angiotensin II is a powerful vasoconstrictor (a substance that constricts blood vessels). By blocking the receptor to which angiotensin II normally attaches, telmisartan stops the hormone having an effect, allowing the blood vessels to expand. This allows blood pressure to drop with a resulting decrease in protein in the urine which may slow down progression of kidney disease. If your cat is losing weight then Semintra may well help. Of course hyperthyroidism causes weight loss too but if your cat is losing any protein in her urine then this will contribute. It would be up to your vet to advise how beneficial Semintra would be to your cat at this stage.

16 September 2016 at 11:11pm


Chrissy Anderson

  • VioVet customer since 2016
  • From: Greater Manchester, United Kingdom

My cat was recently prescribed this with a vague excuse why...and I was told to give him 4kg a day but when I got hone I found that the syringe was in mg/ml? when i rang to query this the vets did not seem to understan what I was asking? can you help


  • VioVet Staff

I can see your confusion. The syringe is telling you that there are 4mg of semintra in 1ml of solution. This is not something you need to worry about though. To simplify things the scale on the syringe from 1-8 represents a kg-bodyweight scale. If your cat weighs 4kg you need to fill the syringe up to 4 on the scale.

21 June 2016 at 10:31pm

Administering Semintra while pregnant


Hello. My 12 year old tabby has sadly been diagnosed with early stage CKD and proteinuria. She also has blood in her urine which is being attributed to idiopathic cystitis as an ultrasound revealed nothing suspicious. She has been prescribed Semintra which I've been giving her for a month every morning.
I've just discovered I'm in the early stages of pregnancy and I see on the leaflet that Semintra should be handled with caution/not at all in pregnancy. If my partner gives her the medication is this adequate precaution? Should I stay away from her completely which I would hate and would be very hard to do when I live with her? Can I still stroke her or is that dangerous to me?
I asked my vet nurse, Dr and pharmacist and due to the new nature of the drug they were not able to offer much advice apart from to get my partner to medicate the cat and stay away from her for an hour afterwards. Please could you advise as I would like a vet's take on it?
Many thanks

  • VioVet Staff

I am sure that close contact with your cat will be completely safe as far as this medication is concerned. There is a theoretical risk if you have a litter tray and you handle that, because the compound is excreted unchanged in the faeces. However I am sure that normal hygiene measures will be fully adequate to protect you there. (A much more real danger to you from a litter tray would be Toxoplasmosis, so please ask your doctor about this if you are not aware of it.) I suppose if she had some residual medication in her mouth and then bit you, there would be a slight risk, but you can assess how likely that really is. Again if she has some in her mouth then grooms herself, some will be present on her coat. However we are getting into the realms of theoretical tiny risks here and there are many greater dangers out there than this. The amount that you could actually ingest through stroking her is ridiculously small and quite insignificant. The danger to pregnant women comes really from being prescribed the medication themselves, so the dose would be immensely higher. Basically as long as you do not have any direct contact with the medication, all will be well. Perhaps wash your hands before eating etc while pregnant, for lots of reasons. Otherwise I do not think this should be a concern of yours now.

I hope your pregnancy goes well in every way and that you enjoy motherhood in all its complexities!

25 November 2015 at 12:25pm




  • VioVet Staff

I would certainly think that Semintra could replace the Fortekor. It might well reduce blood pressure too in time, but by a different mechanism than amlodipine.You could perhaps maintain the amlodipine initially and measure blood pressure periodically while then withdrawing the it. You could certainly find that amlodipine is not needed, depending perhaps on how high the blood pressure has been before. Your vet is best able to advise on this.

25 January 2014 at 11:17pm

Will it hrlp my poor puss prudence aged 20?

sue fisher

Prudence is 20,has ckd hyperthroidism and bp of. 150 .she had just had her medication changed from fortecor to semintra, and akso takes istin and felimazole.
Her illness has occurred in tge last 6 months and sge has deteriorated, lost weight and is quire frail,.
I woukd do anything to make her bettet.
Please can you give me some advice.
Thank you

  • VioVet Staff

Prudence is so old, you must be very proud of her. Semintra is designed for cats just like her and it should help, but nothing will make her young again. It can help to reduce the weight loss by reducing the amount of protein which leaks out in the urine. We would recommend you continue with it.

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