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Sedalin Gel is supplied in a graduated plastic syringe and used to sedate horses. The syringe can be inserted into the corner of the mouth to deposit the palatable gel into a cheak pouch, or Sedalin Gel can be added to food. The active ingredient is ACP (acepromazine) and this produces sedation within 15 to 30 minutes, which lasts for up to 6 or 7 hours. Increasing the dose will increase the level of sedation and prolong the period of effect.
All prices include VAT where applicable.
Yellow-orange transparent gel for oral administration. Each ml contains acepromazine (as acepromazine maleate) 35.0 mg and methyl-4-hydroxybenzoate 0.65 mg and propyl-4-hydroxybenzoate 0.35 mg as preservatives.
For sedation of horses
Moderate sedation: 0.15 mg acepromazine/kg bodyweight.
The dose may be varied to administer between ½ and 1 ½ times the above recommendation according to the level of sedation required, i.e. for mild sedation, administer half the recommended dose and for deeper sedation, administer 1 ½ times the recommended dose.
Because of the difficulties in ensuring the accurate delivery of small doses, the product should only be used in horses of less than 200kg bodyweight in accordance with a benefit / risk assessment by the responsible veterinarian.
The syringe is brought into the animal’s mouth and the suitable dose is pumped into the cheek pouch. The palatable gel can also be mixed with food.
Not for use in animals in shock or post traumatically, or with existing severe emotional excitation or epilepsy.
Sedation lasts for approximately six hours, although the actual time and depth of sedation are very dependent on the status of the individual animal.
Increasing the dosage results in prolonged action and side effects but no greater sedation.
Do not use in cases of post traumatic hypovolemia.
In the case of accidental ingestion contact a physician showing the pack insert or product label to the physician. Wash hands and exposed skin thoroughly after use. Persons with sensitive skin or in continuous contact are advised to wear impermeable gloves. Avoid contact with eyes. If accidental eye contact occurs, flush gently with running water for 15 minutes and seek medical advice if any irritation persists.
Since acepromazine decreases sympathetic nervous system tone, a transient drop in blood pressure may occur after its administration. Acepromazine inhibits temperature regulation.
The following reversible changes are possible in the haemogram: Transient decrease in the erythrocyte count and haemoglobin concentration as well as in thrombocyte and leukocyte counts.
Because it increases prolactin secretion, the administration of acepromazine may lead to disturbances in fertility.
Penile prolapse may occur due to the relaxation of the retractor penis muscles. Retraction of the penis should be visible within two to three hours. If this does not take place, it is advised to contact a veterinary surgeon. Lack of retraction is of particular concern in breeding stallions. Acepromazine has caused paraphimosis sometimes in a sequel to priapism.
Acepromazine should not be used in pregnant or lactating mares.
In stallions the lowest dose range is indicated to minimise prolapse of the penis.
Acepromazine potentiates the action of centrally depressant drugs. The simultaneous use of organic phosphate esters increases the toxicity of acepromazine. Since acepromazine decreases sympathetic nervous system tone, it should not be given at the same time as blood pressure reducing drugs.
Overdosage results in an earlier onset of the sedative symptoms and in a prolonged effect.
Toxic effects are: ataxia, hypotensia, hypothermia, extrapyramidal effects.
Noradrenaline can be used to counteract the cardiovascular effects. Methylamphetamine has been recommended for the treatment of aberrant reactions in horses.
Not authorised for use in horses intended for human consumption.
Simultaneous administration or administration to patients who were treated recently with organophosphates should be avoided, since these molecules enhance the toxic effects of acepromazine.
Simultaneous treatment with blood pressure lowering products should be avoided.
10 ml white, low density polyethylene pre-filled oral dial-a-dose syringe and syringe plunger with white low density polyethylene cap (push fit)
ATC Vet Code: QN05AA04. Acepromazine is a phenothiazine derivate. This group of molecules belongs to the neuroleptica: they depress the central nervous system and exert associated effects on the autonomic system. These effects are due to their interference with different neurotransmitter receptors (dopaminergic, adrenergic) and to their interference with hypothalamic performance.
The desired effects observed after treatment with acepromazine include a general tranquillizing effect, anti-emetic effect and a slight antihistaminic effect. There is no analgesic action. The neuroleptical effects are variable between individual animals.
Acepromazine is partly absorbed from the gastrointestinal tract. It binds extremely well to plasma proteins and is extensively distributed over the body tissues. Plasma levels are usually low. Acepromazine is highly metabolized and excreted in urine. The sedative activity starts within 15-30 minutes and lasts up to 6-7 hours.
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Below are some recent questions we've received regarding Sedalin Gel for Horses, including answers from our team.
Would this be ok to use for a nervous horse being clipped?
She is normally sedated by vets for this but it costs me so much money and she needs clipping again
Sedalin will take the edge off a nervous horse when being clipped but is no where near as potent as a true sedative. There is also a huge variation in its effect on different horses. The only way to know is to give it a go. The other option is Domosedan gel which is stronger and goes under the horses tongue. Both of these products will require a prescription from your vet. Hope this helps. Good luck.
Miss L. Mewes (mewes1127)
If you were to use sedaline on a pony in shock or with severe emotional excitation, what possible reactions or outcomes would there be?
In this situation, the Sedalin might appear to be ineffective, or alternatively might have a more pronounced and prolonged effect. You might see excessive staggering about, or the horse getting cold and then shivering, or other unwanted effects. Essentially it should only be used in horses which are well, although any adverse effects usually get better on their own soon afterwards.
Hi would this be an adequate sedation for my sec d cob to have his teeth done this is the first time he has had his teeth done his previous owner never bothered he can be quiet bolshy and panic in new situations and I know he won't appreciate having the gag on tia
Horses vary in how they respond to this as a sedative. It seems to work better in some than others. Also of course the way the horse is handled makes a big difference. Ideally your own vet should be advising you on this subject as Sedalin and any more potent alternatives are prescription only. They should be prescribed taking into account your individual animal and situation, which only your own vet can assess. For the average horse Sedalin is adequate though.
I am going to use Sedalin to clip pony at 0930 ,planning on giving it to him 30 mins prior ,no feed ,hay etc ,daughter keen to ride in the afternoon ,1230 ish !! What time line is safe for her to do so ,or do I wait till Sunday ?? Many thanks
I would have to advise that stumbling is slightly more likely to occur even after a pony appears to have recovered. This could possibly result in injury to pony or rider. Personally I would not advise riding on the same day after giving this product. Sorry!