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Rilexine is an antibiotic containing cephalexin which is particularly used for skin and urinary infections in dogs and cats. Sometimes long courses are required to completely clear infections of this type, so it is important to continue the whole course without a break. Sensitivity testing is recommended to ensure that Rilexine is appropriate for the causative organism. Rilexine tablets are beef flavoured for ease of administration and are happily taken by most dogs and cats.
All prices include VAT where applicable.
Tablets for oral administration containing cephalexin (as cephalexin monohydrate PhEur) in three strengths:
Rilexine 75 containing 75mg cephalexin
Rilexine 300 containing 300mg cephalexin
Rilexine 600 containing 600mg cephalexin
Cephalexin monohydrate is a bactericidal antibiotic of the cephalosporin family, obtained by hemi-synthesis of the 7 amino-cephalosporanic nucleus.
Cephalexin acts by inhibiting the nucleopeptide synthesis of the bacterial wall. As a result bacterial destruction occurs. Cephalexin is not inactivated by β-lactamases produced by the Gram positive bacteria and which normally affect penicillins.
After oral administration, Cephalexin is absorbed through the intestinal barrier. The plasma peak is observed very quickly (T max. 1.5). Therapeutic skin levels are obtained within 2 hours.
Cephalexin is eliminated as an active form, mainly by the urinary route (85%).
Cephalexin is effective against a wide range of Gram positive and Gram negative bacteria including: Staphylococci, Streptococcus spp., Pneumococci, E. Coli, Klebslella spp, and Salmonella spp.
Treatment of the following infections caused by bacteria sensitive to cephalexin:
Infections of the urinary tract in cats and dogs (such as nephritis and cystitis).
Cutaneous infections (pyoderma) in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.
15 mg Cephalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day):
for a duration of 14 days in cases of urinary tract infection;
at least 15 days in cases of superficial pyoderma;
at least 28 days in cases of deep pyoderma.To achieve this dosage, administer:
one tablet of Rilexine 75 per 5 kg bodyweight
one tablet of Rilexine 300 per 20 kg bodyweight
one tablet of Rilexine 600 per 40 kg bodyweight
Rilexine tablets are well accepted by cats and dogs but may be crushed or added to food if necessary.
In severe or acute conditions the dose may be safely doubled.
Do not use in animals known to be hypersensitive to penicillins and cephalosporins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Special precautions for use in animals
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In case of known renal insufficiency, the dose should be reduced and antimicrobials known to be nephrotoxic should not be administered concurrently.
This product should not be used to treat puppies of less than 1 kg of bodyweight or kittens under 9 weeks of age.
Use of the product deviating from the instructions given in the S.P.C. may increase the prevalence of bacteria resistant to Cefalexin and may decrease the effectiveness of treatment with other cephalosporins and penicillins, due to the potential for cross-resistance.
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological information.
Official, national and regional antimicrobial policies should be taken into account when the product is used.
As the tablets are palatable to animals there is a danger of excessive ingestion. The tablets must therefore be stored out of the reach of animals.
Local treatment of cutaneous and subcutaneous infections in cats should be considered as a complement of the antibiotic treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1- Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations.
2- Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3- If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more-serious symptoms and require urgent medical attention.
Adverse reactions (frequency and seriousness)
Very rare cases of soft faeces and vomiting may be observed in animals during treatment.
Hypersensitivity to Cefalexin is rare, however, the product should not be administered to animals which are known to be hypersensitive to Cefalexin or penicillin.
Allergic cross-reactivity with other β-lactams may occur.
Use during pregnancy, lactation or lay
The product can be used in pregnant and lactating animals.
Interaction with other medicinal products and other forms of interaction
The association of first-generation cephalosporins with aminoglycoside antibiotics and some diuretics such as furosemide can enhance nephrotoxicity risks.
The bactericidal activity of cephalosporins is reduced by concomitant administration of bacteriostatic acting compounds (tetracyclines, chloramphenicol, macrolides and rifampicin).
Keep out of reach of children. Protect from light.
Rilexine 75: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 300: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 600: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Nil.
Tablets for oral administration containing cephalexin (as cephalexin monohydrate PhEur) in three strengths:
Rilexine 75 containing 75mg cephalexin
Rilexine 300 containing 300mg cephalexin
Rilexine 600 containing 600mg cephalexin
Cephalexin monohydrate is a bactericidal antibiotic of the cephalosporin family, obtained by hemi-synthesis of the 7 amino-cephalosporanic nucleus.
Cephalexin acts by inhibiting the nucleopeptide synthesis of the bacterial wall. As a result bacterial destruction occurs. Cephalexin is not inactivated by β-lactamases produced by the Gram positive bacteria and which normally affect penicillins.
After oral administration, Cephalexin is absorbed through the intestinal barrier. The plasma peak is observed very quickly (T max. 1.5). Therapeutic skin levels are obtained within 2 hours.
Cephalexin is eliminated as an active form, mainly by the urinary route (85%).
Cephalexin is effective against a wide range of Gram positive and Gram negative bacteria including: Staphylococci, Streptococcus spp., Pneumococci, E. Coli, Klebslella spp, and Salmonella spp.
Treatment of the following infections caused by bacteria sensitive to cephalexin:
Infections of the urinary tract in cats and dogs (such as nephritis and cystitis).
Cutaneous infections (pyoderma) in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.
15 mg Cephalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day):
for a duration of 14 days in cases of urinary tract infection;
at least 15 days in cases of superficial pyoderma;
at least 28 days in cases of deep pyoderma.To achieve this dosage, administer:
one tablet of Rilexine 75 per 5 kg bodyweight
one tablet of Rilexine 300 per 20 kg bodyweight
one tablet of Rilexine 600 per 40 kg bodyweight
Rilexine tablets are well accepted by cats and dogs but may be crushed or added to food if necessary.
In severe or acute conditions the dose may be safely doubled.
Do not use in animals known to be hypersensitive to penicillins and cephalosporins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Special precautions for use in animals
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In case of known renal insufficiency, the dose should be reduced and antimicrobials known to be nephrotoxic should not be administered concurrently.
This product should not be used to treat puppies of less than 1 kg of bodyweight or kittens under 9 weeks of age.
Use of the product deviating from the instructions given in the S.P.C. may increase the prevalence of bacteria resistant to Cefalexin and may decrease the effectiveness of treatment with other cephalosporins and penicillins, due to the potential for cross-resistance.
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological information.
Official, national and regional antimicrobial policies should be taken into account when the product is used.
As the tablets are palatable to animals there is a danger of excessive ingestion. The tablets must therefore be stored out of the reach of animals.
Local treatment of cutaneous and subcutaneous infections in cats should be considered as a complement of the antibiotic treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1- Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations.
2- Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3- If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more-serious symptoms and require urgent medical attention.
Adverse reactions (frequency and seriousness)
Very rare cases of soft faeces and vomiting may be observed in animals during treatment.
Hypersensitivity to Cefalexin is rare, however, the product should not be administered to animals which are known to be hypersensitive to Cefalexin or penicillin.
Allergic cross-reactivity with other β-lactams may occur.
Use during pregnancy, lactation or lay
The product can be used in pregnant and lactating animals.
Interaction with other medicinal products and other forms of interaction
The association of first-generation cephalosporins with aminoglycoside antibiotics and some diuretics such as furosemide can enhance nephrotoxicity risks.
The bactericidal activity of cephalosporins is reduced by concomitant administration of bacteriostatic acting compounds (tetracyclines, chloramphenicol, macrolides and rifampicin).
Keep out of reach of children. Protect from light.
Rilexine 75: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 300: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 600: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Nil.
Tablets for oral administration containing cephalexin (as cephalexin monohydrate PhEur) in three strengths:
Rilexine 75 containing 75mg cephalexin
Rilexine 300 containing 300mg cephalexin
Rilexine 600 containing 600mg cephalexin
Cephalexin monohydrate is a bactericidal antibiotic of the cephalosporin family, obtained by hemi-synthesis of the 7 amino-cephalosporanic nucleus.
Cephalexin acts by inhibiting the nucleopeptide synthesis of the bacterial wall. As a result bacterial destruction occurs. Cephalexin is not inactivated by β-lactamases produced by the Gram positive bacteria and which normally affect penicillins.
After oral administration, Cephalexin is absorbed through the intestinal barrier. The plasma peak is observed very quickly (T max. 1.5). Therapeutic skin levels are obtained within 2 hours.
Cephalexin is eliminated as an active form, mainly by the urinary route (85%).
Cephalexin is effective against a wide range of Gram positive and Gram negative bacteria including: Staphylococci, Streptococcus spp., Pneumococci, E. Coli, Klebslella spp, and Salmonella spp.
Treatment of the following infections caused by bacteria sensitive to cephalexin:
Infections of the urinary tract in cats and dogs (such as nephritis and cystitis).
Cutaneous infections (pyoderma) in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.
15 mg Cephalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day):
for a duration of 14 days in cases of urinary tract infection;
at least 15 days in cases of superficial pyoderma;
at least 28 days in cases of deep pyoderma.To achieve this dosage, administer:
one tablet of Rilexine 75 per 5 kg bodyweight
one tablet of Rilexine 300 per 20 kg bodyweight
one tablet of Rilexine 600 per 40 kg bodyweight
Rilexine tablets are well accepted by cats and dogs but may be crushed or added to food if necessary.
In severe or acute conditions the dose may be safely doubled.
Do not use in animals known to be hypersensitive to penicillins and cephalosporins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Special precautions for use in animals
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In case of known renal insufficiency, the dose should be reduced and antimicrobials known to be nephrotoxic should not be administered concurrently.
This product should not be used to treat puppies of less than 1 kg of bodyweight or kittens under 9 weeks of age.
Use of the product deviating from the instructions given in the S.P.C. may increase the prevalence of bacteria resistant to Cefalexin and may decrease the effectiveness of treatment with other cephalosporins and penicillins, due to the potential for cross-resistance.
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological information.
Official, national and regional antimicrobial policies should be taken into account when the product is used.
As the tablets are palatable to animals there is a danger of excessive ingestion. The tablets must therefore be stored out of the reach of animals.
Local treatment of cutaneous and subcutaneous infections in cats should be considered as a complement of the antibiotic treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1- Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations.
2- Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3- If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more-serious symptoms and require urgent medical attention.
Adverse reactions (frequency and seriousness)
Very rare cases of soft faeces and vomiting may be observed in animals during treatment.
Hypersensitivity to Cefalexin is rare, however, the product should not be administered to animals which are known to be hypersensitive to Cefalexin or penicillin.
Allergic cross-reactivity with other β-lactams may occur.
Use during pregnancy, lactation or lay
The product can be used in pregnant and lactating animals.
Interaction with other medicinal products and other forms of interaction
The association of first-generation cephalosporins with aminoglycoside antibiotics and some diuretics such as furosemide can enhance nephrotoxicity risks.
The bactericidal activity of cephalosporins is reduced by concomitant administration of bacteriostatic acting compounds (tetracyclines, chloramphenicol, macrolides and rifampicin).
Keep out of reach of children. Protect from light.
Rilexine 75: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 300: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Rilexine 600: Boxes of 140 tablets (20 blisters of 7 tablets per blister).
Nil.
Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.
For UK delivery, we charge the following:
| Order Total | Weight | Delivery |
| £0-£28.99 | Under 2kg | £2.99 |
| 2kg+ | £4.99 | |
| £29-£38.99 | Under 2kg | Free |
| 2kg+ | £4.99 | |
| £39+ | Under 2kg | Free |
| 2kg+ | Free |
Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.
For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.
We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.
Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.
Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.
Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.
To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.
*For full details on returns, see our terms and conditions page.
Below are some recent questions we've received regarding Rilexine Palatable Tablets for Dogs & Cats, including answers from our team.
Ali
My dog has been prescribed Relexine 600 tablets but we are having difficulty getting him to eat them, he is on a restricted diet so can't give inside a treat. Can we crush them into his normal dry food? Is it safe? Thank you.
These tablets are not coated and are perfectly OK to be given crumbled up into pieces. You can given them with food or water. However if mixed with dried food, the pieces will tend to fall to the bottom of the bowl and he will leave them. It would be much better to find a wet food to mix them with. Check with your vet if anything is suitable. If an allergy is suspected, then it is normally safe to give a completely different food item to what he has had before. (Often it is fine to give a little fish in oil, such as sardines, or duck, rabbit, venison etc. You must check with your vet about this first, but 99% of situations this is fine to do for dogs on restricted diets. I would add that the beef flavouring for the Rilexine tablets might be a concern in fact, so again you should check with your vet about this. Beef is often implicated in dietary allergies in dogs.)
Lila
Cn I give rilexine 75 palatable for my kitten age 2 mths cause by flu?
Cat flu is most commonly caused by Feline Herpes Virus-1 (FHV-1), or Feline Calicivirus (FCV). Rilexine would not have any effect on a flu virus but it is commonly used for secondary bacterial infections which are often associated with cat flu. It would be best for you to take your kitten to the vet to get them diagnosed and a suitable treatment in place.
Vaccination is the best way to protect your cat from the viruses mentioned, and this is usually carried out as a young kitten, and a booster given yearly.
We are able to supply prescription-only medication such as vaccines and antibiotics if you can send us a prescription from your vet, so it might be worth checking if this will save you some money.
leanne
My Makita got given this drug ..they are sensitive to certain medication and says on packet not to give to animals that are sensitive ....she had a fit after she took it ...is that due to the drug and the breed ? As I think the vet should of known this
Dogs which are "allergic" to penicillin should not have this drug. Otherwise it is very safe. This is the sensitivity the warning applies to. If a dog reacts to Rilexine it is very unlikely to have a fit, so I should think this is a coincidence. However, there is nothig wrong with asking your vet about this.
If you still feel there might be a problem, you can report this to the authorities by going to https://www.vmd.defra.gov.uk/adversereactionreporting/?AspxAutoDetectCookieSupport=1
Lesley
Can these be safely given to pregnant and lactating bitches
Yes they are suitable for use on pregnant and lactating bitches.
Marion Seviour
what are the side effects of this drug please. My dog takes 1 and 1/2 tablet twice daily. She is a large german shepherd. She is listless and tired and hungry all the time while taking them. Is this normal please. X
Most dogs do not show side effects from this antibiotic at all. A few dogs will display signs of nausea and occasionally abdominal discomfort. These could account for how your dog's behaving, though increased appetite would not fit particularly. It is usual to give the tablets with a meal to reduce any side effects, so make sure you are doing this.
As in the use of any drug, one has to balance the benefits against any possible side effects. It is very likely that your dog will quickly return to normal when you stop the medication. It is possible of course that your dog's behaviour is nothing to do with the medication and is down to some other underlying problem. If in doubt you should of course talk to your own vet.
