UK Registered Veterinary Retailer

Prednidale Tablets (Prednisolone) for Dogs & Cats

Prednidale Tablets (Prednisolone) for Dogs & Cats

Images are for illustration purposes only. Packaging may change from time to time and images on our website may or may not be updated.

  • 25mg Tablets » Priced per Tablet £1.09


Prednidale 5 mg tablets are used to treat conditions characterised by inflammation or allergic reactions in cats and dogs. These conditions can show symptoms affecting the skin, gut, lungs and airways, locomotory system and the blood, hence Prednidale can be used to treat illnesses with wide ranging symptoms. Prednidale has extensive effects in the body which are of great benefit where used appropriately. Care needs to be taken to ensure that the condition being treated justifies steroid medication, to avoid unwanted side effects. In higher doses, Prednidale can be used to treat autoimmune problems and some forms of neoplasm.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

25mg Tablets » Priced per Tablet

Prednidale Tablets

Qualitative and quantitative composition

Prednidale 5 mg tablets for dogs and cats:

1 tablet contains: Active substance:

Prednisolone 5 mg

Prednidale 25 mg tablets for dogs:

1 tablet contains: Active substance:

Prednisolone 25 mg

Pharmaceutical form

Prednidale 5 mg tablets for dogs and cats:

Tablet. White, circular, flat faced tablets with a breakline and PL5 imprinted on one face and CP or DP on the reverse.

No data has been provided to demonstrate reproducible halving of the tablets.

Prednidale 25 mg tablets for dogs:

Tablet. White, 11 mm circular tablets.

Clinical particulars

Target species

Prednidale 5 mg tablets for dogs and cats:

Dogs and cats.

Prednidale 25 mg tablets for dogs:


Indications for use

Prednidale 5 mg tablets for dogs and cats:

For the treatment of inflammatory and allergic diseases, including some autoimmune diseases and some neoplastic conditions in cats and dogs.

Inflammatory, allergic and autoimmune processes may be involved in cutaneous, alimentary, respiratory, musculoskeletal and haematological manifestations of disease.

Prednidale 25 mg tablets for dogs:

For the treatment of inflammatory and allergic diseases, including some autoimmune diseases and some neoplastic conditions, in dogs.

Inflammatory, allergic and autoimmune processes may be involved in cutaneous, alimentary, respiratory, musculoskeletal and haematological manifestations of disease.


Do not use in animals with renal insufficiency, diabetes mellitus or corneal ulceration.

Do not use in animals recieving vaccines containing live organisms.

Do not use in pregnant animals.

Special warnings for each target species

There are no special warnings required for either target species.

Special precautions for use in animals

Pharmacologically-active dose levels may lead to atrophy of the adrenal cortex, resulting in adrenal insufficiency. This may become apparent particularly after withdrawal of corticosteroid treatment.

Adrenal insufficiency may be minimised by institution of alternate-day therapy if practical. The dosage should be reduced and withdrawn gradually to avoid precipitation of adrenal insufficiency.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Gloves should be worn to administer the product and you should wash your hands immediately after administration of the product.

In the event of accidental ingestion, particularly by a child, seek medical advice and show the doctor the label or package leaflet.

Adverse reactions

Administration of single high doses are generally tolerated well, but medium to long-term use may provoke reactions.

Corticosteroid therapy may lead to increased time in the healing of wounds and to a reduction in the ability of the body to resist infection. Appropriate anti-infective therapy may be required.

Use during pregnancy and lactation

Corticosteroids are not recommended for use in pregnant animals. Studies in laboratory animals have shown that administration during early pregnancy may cause foetal abnormalities. Administration during the later stages of pregnancy may cause abortion or early parturition.

Insignificant amounts of prednisolone are generally eliminated in the milk of lactating animals, and therefore such use is not contraindicated.


There are no known interactions of significance in veterinary medicine.

Amounts to be administered and administration route

For oral administration.

Dogs and cats: 0.1 - 2.0 mg per kg body weight per day.

A single administration may be sufficient for certain conditions such as anaphylaxis, but for more general treatment, treatment for one to three weeks at the above dosage levels may be required. Dosage levels should be monitored carefully to ensure that the lowest effective dose is used. To minimise the risk of adrenal insufficiency, alternate day treatment may be implemented, using dose levels that adequately control the symptoms. Dogs should be dosed in the morning and cats should be dosed at night to coincide with the endogenous cortisol peak.

Higher dose levels may be used in animals with tumours responsive to corticosteroid therapy. In these cases, the dosage level is related to the surface area of the animal and dose levels of between 20 mg per m2 and 60 mg per m2 have been found to be useful. The potential risks associated with these high dose levels should be assessed before commencing treatment.

Prednidale 5 mg tablets for dogs and cats: The tablets are divisible.


Signs of overdosage should be treated symptomatically.

Pharmacological particulars

Pharmacotherapeutic group: Corticosteroid for systemic use.

ATCvet code: QH02AB06

Pharmacodynamic properties

Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressant properties. It possesses only slight mineralocorticoid activity. Prednisolone is used to suppress the clinical manifestations of a wide range of disorders.

Pharmacokinetic properties

Prednisolone is readily absorbed from the gastro-intestinal tract. Peak plasma concentrations are reached one to two hours after administration, with a plasma half-life of between two and three hours. It is extensively bound to plasma proteins. It is excreted in the urine as free and conjugated metabolites and parent compound. It has a biological half-life of several hours, making it suitable for alternate-day therapy.

Pharmaceutical particulars

Shelf life

Prednidale 5 mg tablets for dogs and cats:

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

Prednidale 25 mg tablets for dogs:

Shelf life of the veterinary medicinal product as packaged for sale: 48 months.

Special precautions for storage

Do not store above 25°C. Store in tightly closed original container. Store in a dry place.

Immediate packaging

Prednidale 5 mg tablets for dogs and cats:

Polypropylene tubs with a low density polyethylene cap (push-fit) with a tamper evident ring, containing 500 or 1000 tablets.

Prednidale 25 mg tablets for dogs:

Polypropylene containers with low density polyethylene push-fit tamper evident closures containing 100 tablets.


Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Marketing Authorisation Holder (if different from distributor)

Dechra Limited, Snaygill Industrial Estate, Keighley Road, Skipton, North Yorkshire, BD23 2RW, United Kingdom.

Marketing Authorisation Number

Prednidale 5 mg tablets for dogs and cats: Vm 10434/4009

Prednidale 25 mg tablets for dogs: Vm 10434/4008

Date of the first authorisation or date of renewal

Prednidale 5 mg tablets for dogs and cats:

14 August 1998

Prednidale 25 mg tablets for dogs:

19 November 2007

Date of revision of the text

Prednidale 5 mg tablets for dogs and cats:

September 2016

Prednidale 25 mg tablets for dogs:

September 2016

Any other information

For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.

Legal category

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (12)

Q & A

Below are some recent questions we've received regarding Prednidale Tablets (Prednisolone) for Dogs & Cats, including answers from our team.

25 March 2018 at 5:32pm

Prednidale, withdrawal symptoms regarding my dog.

David tobin

My dog, 16 yrs old, has been on this tablet for a week, have now dropped dose to half tablet. Is there any withdrawal symptoms. ..

  • Veterinary Advisor

Steroids can cause adrenal insufficiency if stopped too quickly. Signs include lethargy, lack of appetite, vomiting and diarrhoea. However the dose is reduced and withdrawn gradually to avoid this. If you reduce the dose as advised by your vet then your dog is unlikely to show signs of adrenal insufficiency but you should contact your vet immediately if he does.

24 May 2015 at 11:27am

Can humans take these tablets


Are these the same as prednisone for humans

  • Non-Executive Director

Theoretically these do contain the same ingredient. However tablets which are licensed for use in animals are not licensed for us in humans, and vice-versa. It might be possible that the inert ingredients which make up the rest of the tablet could affect things and they have not been reliably tested. You are supposed to stick to using tablets as per their license and we can never advise otherwise.

19 May 2015 at 8:41am

Interaction with joint supplements


Can my dog continue to take joint supplements with this medictation?

  • Non-Executive Director

No sort of adverse interaction would be expected from using this drug with joint supplements. It should be perfectly safe.

17 May 2015 at 8:14pm

Are the tablets dissolvable?


My cat has been prescribed prednidale and I'd like to know if it is dissolvable in water? He's on other liquid oral medication which he takes reasonably well from a syringe, so I'm hoping I could do the same with the steroid. Thank you.

  • Non-Executive Director

I do not think this dissolves, or can be given effectively in a drink. The tablets have very little flavour though so it should be possible to give broken up into a little food. Use something which is only ever given as a treat, never a meal, and kept as a special treat. A mashed up prawn works for some cats and these can be kept in the freezer and just one used at a time. Never give lots though, or you will lose the "treat" concept.

10 April 2015 at 9:52am



Hiya my puppy has been on this medication since Christmas and he's losing hair is that a side effect?

  • Non-Executive Director

Sometimes this can happen, but it is not ideal. I have to wonder if a puppy should be on them for months anyway. They are very good for short-term use, say a few days, but ideally a young dog would not be put on them for a long time. I presume your vet has good reason to do this, but it would be worth checking to see if there is something else which could be done. I think you should ask your vet about this.

25 March 2014 at 4:21am

Dog keeps weeing


My dog has a ear infection the vet has put him on prednidale 25mg but he's drinking bowls and bowls of water and he's weeing a lot so much so he carnt hold it in until he gets out side and he's doing it in the house he never messes in the house normally is this normal on these tablets

  • Non-Executive Director

25mg of prednisolone would be a huge dose for an infection and it would indeed make your dog very thirsty and produce loads of urine. I think that either you misunderstand the problem your dog has, or there is a mistake somewhere and your dog should not be on prednisolone 25mg. If your dog has an "auto-immune" disease, then 25mg might be appropriate. If it has an infection, it would not. I suggest you ask your vet about this and say that the side effects are making things difficult for you. It might be possible to change the medication.

17 January 2014 at 10:38pm

How to take

Janet Paton

Can these tablets be crushed when given with food.

  • Non-Executive Director

These prednisolone tablets can be given whole, directly into the mouth, or crushed and given with food. It should not make any difference. The are not coated or flavoured and it does not matter how they are given, including with or without food.