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Prazitel Plus Tablets for Dogs are an effective multi-wormer containing three different ingredients to cover all the intestinal worms likely to be found. A single dose is effective and should be given at a dose rate of up to 1 tablet per 10kg bodyweight for Prazitel Plus and 1 tablet per 35kg bodyweight for Prazitel Plus XL.
Prazitel Tablets for Cats are for the treatment of cats with mixed infections of nematodes and cestodes, including Ascarids, Hookworms, Whipworms and Tapeworms. Each tablet is flavoured for palatability and contains 20mg Praziquantel and 230g Pyrantel embonate. Use 1 tablet per 4kg of bodyweight.
Tablet size reference:
Cat tablets are circular, approximately 1cm in diameter and are scored down the middle to be easily divided into halves.
Dog Plus tablets are ciruclar, approximately 1.3cm in diameter and are scored twice, so can be broken into quarters.
Dog Plus XL tablets are oval, apprimately 2.5cm in length, 1.4cm at the widest point, and can be broken into halves.
Tablets can be given directly or mixed into food.
If necessary, break the tablets into halves or quarters to make administration by mouth or disguised in food easier.
Summary of Product Characteristics
1. NAME OF THE VETERINARY MEDICINAL PRODUCT
Prazitel 230/20 mg Flavoured Film-Coated Tablets for Cats
Milaxyn 230/20 mg Flavoured Film Coated Tablets for Cats (Germany)
Prazinon 230/20 mg Flavoured Film Coated Tablets for Cats (Croatia)
Prazitel 230/20 mg Film-Coated Tablets for Cats (Finland)
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Each film-coated tablet contains Pyrantel embonate 230 mg and Praziquantel 20 mg.
For the full list of excipients, see section 6.1.
3. PHARMACEUTICAL FORM
Film-coated tablets.
A white to off white round, biconvex coated tablet with a breakline on one side and plain on the other side.
The tablet can be divided into equal halves.
4. CLINICAL PARTICULARS
4.1 Target species
Cats.
4.2 Indications for use, specifying the target species
For the treatment of mixed infections caused by the following gastrointestinal roundworms and tapeworms:
Roundworms: Toxocara cati, Toxascaris leonina,
Tapeworms: Dipylidium caninum, Taenia taeniaeformis, Echinococcus multilocularis.
4.3 Contraindications
Do not use simultaneously with piperazine compounds.
Do not use in kittens less than 6 weeks of age.
Do not use in animals with known hypersensitivity to the active substances or to any of the excipients.
4.4 Special warnings for each target species
Fleas serve as intermediate hosts for one common type of tapeworm – Dipylidium caninum. Tapeworm infestation is certain to reoccur unless control of intermediate hosts such as fleas, mice, etc. is undertaken.
Parasitic resistance to a certain class of anthelmintics can occur after frequent and repeated use of an anthelmintic from this class.
4.5 Special precautions for use
Special precautions for use in animals
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In the interests of good hygiene, persons administering the tablets directly to the cat, or by adding them to the cat’s food, should wash their hands afterwards.
In case of accidental ingestion, seek medical advice and show the package leaflet to the physician.
4.6 Adverse reactions (frequency and seriousness)
None known.
4.7 Use during pregnancy, lactation or lay
Do not use during pregnancy but may be used during lactation.
4.8 Interaction with other medicinal products and other forms of interaction
Do not use simultaneously with piperazine compounds.
4.9 Amounts to be administered and administration route
To ensure administration of a correct dose, body weight should be determined as accurately as possible.
Dosage
The recommended dose is: 20 mg/kg pyrantel (57.5 mg/kg pyrantel embonate) and 5 mg/kg praziquantel. This is equivalent to 1 tablet per 4 kg bodyweight.
| Body weight | tablets |
| 1.0 - 2.0 kg | ½ |
| 2.1 - 4.0 kg | 1 |
| 4.1 - 6.0 kg | 1 ½ |
| 6.1 - 8.0 kg | 2 |
Administration and duration of treatment
Single oral administration. The tablet should be given directly to the cat, but if necessary can be disguised in food.
In ascarid infestation, especially in kittens, complete elimination cannot be expected, so a risk of infection for humans can persist. Repeat treatments should, therefore, be carried out with a suitable roundworm product at 14 day intervals until 2-3 weeks after weaning.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
After doses higher than 5 times the recommended dose, signs of intolerance such as vomiting have been observed.
4.11 Withdrawal period(s)
Not applicable.
5. PHARMACOLOGICAL PROPERTIES
Pharmacotherapeutic group: Anthelmintics, praziquantel combinations.
ATC vet code: QP52AA51
5.1 Pharmacodynamic properties
This product contains anthelmintics active against gastrointestinal roundworms and tapeworms. The product contains two active substances, as follows:
and
Pyrantel acts as a cholinergic agonist. Its mode of action is to stimulate nicotinic cholinergic receptors of the parasite, induce spastic paralysis and thereby allow expulsion from the gastro-intestinal (GI) system by peristalsis.
Praziquantel is very rapidly absorbed and distributed throughout the parasite. Both in vitro and in vivo studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolization of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, especially calcium.
In this fixed combination, pyrantel is active against the following ascarids: Toxocara cati, and Toxascaris leonina. Praziquantel is effective against tapeworms in particular Dipylidium caninum and Taenia taeniaeformis.
Since it contains praziquantel, the product is effective against Echinococcus multilocularis,.
5.2 Pharmacokinetic particulars
Praziquantel is rapidly absorbed, metabolised and distributed in the body. It is also believed to be excreted back into the intestinal lumen by the mucous membrane.
Following administration of the product to cats, peak plasma concentrations of praziquantel were achieved by approximately 2 hours.
Pyrantel is poorly absorbed so it is expected that a large proportion of the administered dose remains in the GIT where it exerts its therapeutic effect and it is excreted largely unchanged in the faeces.
Following administration of the product to cats, peak plasma concentrations of pyrantel were achieved by approximately 3 hours.
6. PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Core tablet:
Maize starch,
Microcrystalline cellulose,
Crospovidone
Magnesium stearate,
Colloidal anhydrous silica,
Film coat
Grilled meat flavour
Opadry II White consisting of Polyvinyl Alcohol, Titanium Dioxide (E171), Macrogol 3350 and Talc (E553b)
6.2 Incompatibilities
Not Applicable
6.3 Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 4 years
Discard unused half tablets.
6.4. Special precautions for storage
This veterinary medicinal product does not require any special storage conditions
The product is presented in either:
Individual blisters made up of a PVC/PE/PCTFE white opaque copolymer and a 20µm heatseal
lacquer/aluminium containing 2, 4, 6, 8, 10, 12, 14, 16, 18 or 20 tablets.
or
Individual blisters made up of 45µm PVC/aluminium/orientated polyamide and a 20µm heatseal lacquer/aluminium containing 2 or 8 tablets.
The blisters are packed into cartons containing either: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 24, 28,
30, 32, 36, 40, 42, 44, 48, 50, 52, 56, 60, 64, 68, 70, 72, 76, 80, 84, 88, 92, 96, 98, 100, 104,
106, 108, 112, 116, 120, 128, 136, 140, 144, 150, 152, 160, 168, 176, 180, 184, 192, 200, 204,
206, 208, 216, 224, 232, 240, 248, 250, 280, 300, 500 or 1000 tablets
Not all pack sizes may be marketed.
6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
7. MARKETING AUTHORISATION HOLDER
Chanelle Pharmaceuticals Manufacturing Ltd.,
Loughrea,
Co. Galway,
Ireland
8. MARKETING AUTHORISATION NUMBER(S)
VPA10987/101/001
All prices include VAT where applicable.
| Overall | |
| Effectiveness | |
| Ease Of Use | |
| Value For Money | |
| Absence Of Side Effects |
Only verified purchasers of this product can leave a review.
As good as any other.
Customer recommends this product
Dog ate it easily but had slight upset stomach
Customer recommends this product
Fine
Customer recommends this product
Wouldn’t use this again. Made dog very sick and off colour for two days.
Customer does not recommend this product
Good
Customer recommends this product
1 person found this review helpful
Below are some recent questions we've received regarding Prazitel Worming Tablets for Dogs & Cats, including answers from our team.
Elizabeth White
How often do I administer this wormer.
Worming every 3 months is recommended for the average cat. If your cat is a prolific hunter then monthly dosing during the hunting season is advised. Equally if your cat is indoors only and the risk of scavenging is almost negligible then every 6 months can suffice.
Yifat wallach
My dog is 33 Kg. which tablet will fit him?
The difference depends on your dog's weight and the doseage required. A single dose is effective and should be given at a dose rate of up
to 1 tablet per 10kg bodyweight for Prazitel Plus and 1 tablet per 35kg
bodyweight for Prazitel Plus XL.
I would advise 1 tablet of Prazitel Plus XL for your 33kg dog.
Becky
Can this product be given to puppies?
This wormer can be used on puppies from 2 weeks of age.
Susie
My mother cat has worms but only gave birth two weeks ago. Is it safe to give her a wormer?
Yes, this is perfectly safe. The kittens are likely to have worms also, as some types of roundworm can get into the mammary glands, and pass to the kittens in their mother's milk. While they are not weaned and she is cleaning them up when they go to the toilet, the kittens will be a source of infection for her also.
I'd recommend worming her with Prazitel every 4 weeks until they are fully weaned. The kittens can't have Prazitel until they at least 6 weeks old and weighing at least 1kg. While they're small, I recommend using something like Panacur Paste or Panacur Suspension with them at 2, 5, 8 and 12 weeeks of age (or just before they leave your home).
I hope this helps!
Is this for both worms
Are these for both type of worms
Yes, Prazitel treats all common types of roundworms (nematodes) and tapeworms (cestodes) found in dogs and cats, including Ascarids, Hookworms, and Whipworms. It unfortunately cannot treat heartworm though, you would need to ask your vet to prescribe a product for this if your dog is in a high risk area.
Pamelite
Prazitel Worming Tablets for Dogs & Cats
i did not receive a leaflet for use with the packet. i do not know how frequently to administer this tablet. is it once every four months ... or?
The usual frequency of administration for a wormer such as this would be once every 3 months. However it depends a bit on each dog. If your dog is a particular scavenger then you could worm up to once a month but usually every 3 months is enough.
Clare Ratcliffe
Is this wormer ok to use on kittens?
This wormer is fine to use in kittens over 6 weeks of age.
Nat c
A couple of my dogs weigh 12kg. Do they need two whole tablets or one and a half? Can I give half a tablet? Cheers
The correct dose is one and a half tablets to each dog.
Lucky13
Does the treat lungworm and roundworm as well? Do you need a prescription for this?
You do not need a prescription for this wormer. It treats tapeworms and all the main round worms, but is not claimed to have any activity against lungworm. The only product which is known to be helpful against the main type of lungworm in dogs is prescription-only (Advocate).
Sandra Crook
I wormed my dog 10 days ago and have just found out she is pregnant. Will this drug harm the pups?
Giving a worm dose in early pregnancy is not recommended because on principle this should be avoided with any medication. Usually there is no particular reason to worm a bitch in early pregnancy anyway, so the advice would be not to do it. That does not mean however that it is actually likely to be harmful. The chances of you noticing any adverse response are very slim. Many dogs are given worm doses while pregnant and it does not seem to cause a problem. I would not have advised that you did this if you had known she was pregnant, but now that it is done you should not worry. I very much doubt if it will cause any trouble at all.
