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Norodine contains two ingredients which act synergistically to block important metabolic pathways in bacteria. This results in efficacy against a wide range of different bacteria and so Norodine can be used for many types of infection. It is used for infections affecting the respiratory and alimentary systems, as well as many other types of soft tissue infection, including infected wounds and septicaemia. The different formulations of Norodine are intended for use in dogs, cats, horses and calves.
All prices include VAT where applicable.
Each tablet contains:Active substance(s): Trimethoprim 200 mgSulfadiazine1.0 gExcipients:For a full list of excipients, see section Pharmaceutical Particulars
For a full list of excipients, see section Pharmaceutical Particulars
A white bolus-shaped tablet, deeply scored on one face.
Norodine Bolus is indicated primarily for the treatment of bacterial scours but may also be used for the treatment of acute salmonellosis and bacterial pneumonia.
Norodine Bolus should not be administered to animals with functionally mature rumens.
No special precautions.
Special precautions for use in animals
Official, national and regional antimicrobial policies should be taken into account when the product is used.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Take care to avoid skin and eye contact. Protective gloves should be worn whilst handling this product. Wash hands and exposed skin after use.
Sulphonamides may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to sulphonamides may lead to cross reactions with other antibiotics. Allergic reactions to these substances may occasionally be serious.
No known interactions.
Oral: One tablet per 40 kg bodyweight daily. This gives 30 mg of combined active ingredients per kg bodyweight.
Treatment should be repeated daily until two days after the symptoms have resolved, but in cases of salmonellosis and bacterial pneumonia treatment should be continued for 5 consecutive days. Treatment must not be continued for more than 5 days.
The product may be administered whole, by hand or balling gun, or dispersed in water. Dosage by dispersion in water: Disperse each bolus by shaking in about 300 ml of water in dosing bottle. This may be facilitated by crushing the bolus before placing it in the bottle. After dosing by this method any unused material should be discarded.
To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
Meat: 15 days.
Pharmacotherapeutic group: Antibacterials for systemic use.
ATC Vet Code: QJ01EW10
Sulphadiazine (SDZ) inhibits the incorporation of para-aminobenzoic acid into folic acid and trimethoprim (TMP) inhibits the enzyme dihydrofolate reductase (DHFR) which converts dihydrofolic acid into tetrahydrofolic acid. TMP and SDZ act together synergistically with a double-blockage mode of action. The combination is bactericidal inhibiting sequential steps in the synthesis of purines which are required for DNA synthesis. TMP-SDZ combinations have a broad bactericidal action against many gram-positive and gram-negative aerobic bacteria, and a large proportion of anaerobic bacteria.
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years
Do not store above 25°C.
Store in a dry place.
Protect from light.
White or grey polypropylene 'securitainers', closed with white, low density polyethylene, tamper evident lids. Each container contains 20 or 50 tablets.
Not all pack sizes may be marketed.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Norbrook Laboratories Limited
17th December 1986
Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.
For UK delivery, we charge the following:
Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.
For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.
We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.
Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.
Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.
Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.
To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.
*For full details on returns, see our terms and conditions page.
Below are some recent questions we've received regarding Norodine Antibiotic, including answers from our team.
of tabletswhat is the doseage for a 40kg dog per day
The dose specified by Norbrook for a 40kg dog would be 2.5 tablets daily. However Norodine is often given twice daily so it would be best to consult your vet for the dose they recommend.
I run a sales prep yard and need routine antibiotics/bute/gastroguard etc etc for a number of horses, up to 12.
Can I get my vet to write a general prescription covering all these drugs or do I need to lodge a specific prescription every time I need to order?
Basically we can supply pretty much whatever your vet allows on the prescription. If you ordered vast amounts which were clearly above what a yard of your size could use, we would have to question it. However as long as your purchases seem reasonable for what you are doing, we will supply whatever we can. That means it is down to your vet to prescribe whatever he/she thinks is reasonable in the circumstances. If your vet is happy to provide a prescription which allows for all the medication you require, then you can send it to us and just draw amounts of medication off that one prescription as you need them. You might need a new prescription every 6 months or a year, but it could cover whatever you need. However this is entirely down to your own vet and he/she is given great freedom within the law to prescribe whatever is reasonable in the circumstances. Vets are given guidelines from the RCVS and different vets interpret these in slightly different ways, but essentially it is up to your own vet.