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Nobivac Pi Injection for Dogs

Nobivac Pi Injection for Dogs

  • Box of 10 Doses £82.00
  • Box of 50 Doses £401.99
  • Single Dose £8.50

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£8.50 to £401.99

Description


Nobivac Pi provides protection against Parainfluenza virus in dogs. It is supplied as a freeze-dried powder to be mixed with solvent before use.

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  • Landline: 01582 842096
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  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

Single Dose

Nobivac Pi Lyophilisate and Solvent for Suspension for Injection for Dogs

Qualitative and quantitative composition

1 dose of 1 ml contains:

Active substance:

Live attenuated canine parainfluenza virus (CPi) strain Cornell: ≥ 5.5 log10 and ≤ 7.3 log10 TCID50*.

* TCID50 = median Tissue Culture Infective Dose

Solvent:

Nobivac Solvent (Phosphate buffered diluent).

For the full list of excipients, see the Pharmaceutical Particulars section.

Pharmaceutical form

Lyophilisate and solvent for suspension for injection.

Lyophilisate: off-white or cream-coloured pellet.

Solvent: clear colourless solution.

Reconstituted product: off-pink or pink suspension.

Clinical particulars

Target species

Dogs

Indications for use

For active immunisation of dogs from the age of 8 weeks onwards to reduce clinical signs of canine para-influenza infection and to reduce viral shedding.

Onset of immunity: 4 weeks after vaccination.

Duration of immunity: has not been demonstrated, but an anamnestic response is produced in dogs given a revaccination one year after basic vaccination.

Contra-indications

None.

Special warnings for each target species

A protective antibody titre is not accomplished in all vaccinated dogs.

As maternally derived passive antibodies can interfere with the response to vaccination in very young animals, a final dose at 10 weeks of age or older is recommended.

Special precautions for use

Vaccinate only healthy dogs.

Sterile equipment should be used for administration.

Operator warnings

In the case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions

In very rare cases, some dogs may show discomfort during injection.

In very rare cases, a diffuse swelling, up to 5 mm in diameter, may be observed at the site of injection; occasionally this swelling may be hard and painful and last for up to 3 days post injection.

In very rare cases, hypersensitivity reactions may occur. In the event of an anaphylactic reaction appropriate treatment such as adrenaline should be administered without delay.

The frequency of adverse reactions is defined using the following convention:

- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)

- common (more than 1 but less than 10 animals in 100 animals)

- uncommon (more than 1 but less than 10 animals in 1,000 animals)

- rare (more than 1 but less than 10 animals in 10,000 animals)

- very rare (less than 1 animal in 10,000 animals, including isolated reports).

Use during pregnancy, lactation or lay

Nobivac Pi has been shown to be safe for use in pregnant bitches that have been vaccinated before pregnancy with the Pi vaccine of the Nobivac series.

Interactions

Safety and efficacy data (viral excretion) are available which demonstrate that this vaccine can be mixed and administered with the inactivated vaccines of the Nobivac series against canine leptospirosis caused by all or some of the following serovars: L. interrogans serogroup Canicola serovar Canicola, L. interrogans serogroup Icterohaemorrhagiae serovar Copenhageni, L. interrogans serogroup Australis serovar Bratislava, and L. kirschneri serogroup Grippotyphosa serovar Bananal/Liangguang.

The product information of the relevant Nobivac vaccines should be consulted before administration of the mixed product. When mixed with Nobivac leptospirosis vaccines at annual revaccination, it has been established that there is no interference with the anamnestic response induced by the injectable canine parainfluenza virus component.

After administration with one of the leptospirosis vaccines, a mild and transient increase in body temperature (≤ 1°C) may occur for a few days after vaccination, with some pups showing less activity and/or a reduced appetite. A small transient swelling (≤ 4 cm), which can occasionally be firm and painful on palpation, may be observed at the site of injection. Any such swelling will either have disappeared or be clearly diminished by 14 days post-vaccination.

After mixed administration of an overdose of Nobivac Pi and an overdose of the leptospirosis vaccines of the Nobivac series, transient local reactions such as diffuse to firm swellings from 1 to 5 cm in diameter may be observed, usually these will persist no longer than 5 weeks, however some may take a little longer to completely disappear.

Safety and efficacy data are available which demonstrate that this vaccine can be mixed and administered with the inactivated vaccine of the Nobivac series against rabies or the inactivated vaccine against rabies and leptospirosis, where applicable. After administration with the rabies containing vaccines transient local reactions such as diffuse to firm swellings from 1 to 4 cm in diameter may be observed for up to 3 weeks after vaccination. The swellings may be painful for up to 3 days post dosing.

When Nobivac Pi is used with any of the other Nobivac vaccines referred to above, the minimum vaccination age for each vaccine must be taken into account such that at the time of vaccination, the dogs are at or older than the oldest minimum vaccination age for the individual vaccines.

No information is available on the compatibility of this vaccine when used with any other veterinary medicinal product except the products mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Amounts to be administered and administration route:

One ml solvent or 1 ml (1 dose) of inactivated vaccine (as specified in section 4.8) must be used to reconstitute the freeze-dried Nobivac Pi vaccine.

One ml (1 ml) of reconstituted vaccine should be given by subcutaneous injection.

Vaccination schedule:

- Basic vaccination:

• Before the age of 12 weeks:

Two vaccinations, each with a single dose: the first vaccination from the age of 8 weeks onwards and the second vaccination 2 - 4 weeks later.

• From the age of 12 weeks onwards:

Single vaccination, with one dose per animal.

- Revaccination:

Every year with a single dose.

Overdose

Not different from a single dose. In some dogs the swelling may be more painful or may be observed for a longer period.

Withdrawal periods

Not applicable.

Pharmacological particulars

Immunological properties:

Pharmacotherapeutic group: Live viral vaccine for dogs

ATCvet code: QI07AD08.

Pharmaceutical particulars

Excipients

Vaccine: Sorbitol, Gelatin, Pancreatic digest of casein, Disodium phosphate dehydrate, Water for injections.

Solvent: Disodium phosphate dihydrate, Potassium dihydrogen phosphate. Water for injections.

Major incompatibilities

Do not mix with any other vaccine except the diluent supplied with the product or with the lepto and/or rabies vaccines of the Nobivac series (where these products and their combined use are authorised).

Shelf life

Shelf-life of the veterinary medicinal product as packaged for sale:

2 years at 2 – 8 °C (after storage by the manufacturer for 29 months at -20 °C).

Shelf-life after dilution or reconstitution according to directions: Use within 30 minutes.

Shelf life of the solvent: 4 years.

Special precautions for storage

Vaccine:

Store in a refrigerator (2 – 8 °C).

Do not freeze.

Protect from light.

Care should be taken to avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.

Solvent:

Store below 25 °C if stored independently from the vaccine.

Immediate packaging

Vaccine:

Vial of hydrolytical class type I (Ph. Eur.) glass closed with a halogenobutyl rubber stopper and a colour coded aluminium cap.

Solvent:

Vial of hydrolytical class type I (Ph. Eur.) glass closed with a halogenobutyl rubber stopper and a colour coded aluminium cap.

Pack sizes: Carton or plastic box with 5, 10, 25 or 50 single dose vials.

Solvent may be packed together with the vaccine or separately.

Not all pack sizes may be marketed

Disposal

Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities.

Marketing Authorisation Holder (if different from distributor)

Intervet International BV, NL represented by Intervet UK Ltd.

Marketing Authorisation Number

Vm 06736/4034

Date of the first authorisation or date of renewal

31 January 2002.

Date of revision of the text

09 February 2017.

Any other information

For animal treatment only. Keep out of the sight and reach of childen.

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Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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