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Levacide

  • 7.5% Low Volume Drench » 1 litre Bottle £29.99
  • 7.5% Low Volume Drench » 2.5 litre Bottle £52.49
  • 7.5% » 500ml Bottle £13.99
  • Pour-on » 2.5 litre Bottle £172.49

Selection of 4 products from

£13.99 to £172.49

Levacide is a broad spectrum wormer for use in cattle and sheep. It is available as a drench, a pour-on, or as an injection. The active ingredient is levamisole which is one of the major anthelmintics, with good activity against the main worms found in farm animals. The major worm species covered include Lungworms (Dictyocaulus spp.) and Gastrointestinal worms (Trichostrongylus spp; Cooperia spp; Ostertagia spp (except inhibited Ostertagia larvae in cattle); Haemonchus spp; Nematodirus spp; Bunostomum spp; Oesophagostomum spp; and Chabertia spp.)

PLEASE NOTE: When dosing young animals, it is extremely important to accurately weigh each individual and calculate the correct dose for them to avoid overdosing. The product has a narrow safety margin in animals under 10kg, so if you are in any doubt, seek veterinary assistance before administering.

3% Drench for Cattle & Sheep

Presentation

A clear yellow oral solution containing:
Levamisole Hydrochloride 3.0 % w/v

Uses

Levacide 3% Drench is a broad spectrum anthelmintic for use in the treatment and control of nematode infections in cattle and sheep.

Levacide 3% Drench should be used in cases of parasitic gastro-enteritis and lungworm disease caused by mature and developing immature forms of those organisms sensitive to treatment with levamisole hydrochloride.

Lungworms: Dictyocaulus spp.

Gastrointestinal worms: Trichostrongylus spp; Cooperia spp; Ostertagia spp (except inhibited Ostertagia larvae in cattle); Haemonchus spp; Nematodirus spp; Bunostomum spp; Oesophagostomum spp; and Chabertia spp.

Dosage & Administration

Levacide 3% Drench should be administered as an oral drench. Dosing must be carried out accurately using a dosing gun system at a rate of 7.5mg levamisole hydrochloride/kg bodyweight.

Withdrawal Period

Animals must not be slaughtered for human consumption during treatment.

Cattle may be slaughtered for human consumption only after 14 days from the last treatment. Sheep may be slaughtered for human consumption only after 21 days from the last treatment.

This product must not be used in cattle and sheep producing milk for human consumption.

Contraindictions, Warnings etc

Levacide 3% Drench is safe for use in cattle and sheep at the recommended dosages. However, if the recommended dosages are exceeded, animals may exhibit signs of impaired motor functions such as muscle tremors and increased salivation which are of a temporary nature.

To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.

Levacide 3% Drench may be administered to pregnant or lactating animals. However, care should be taken when treating heavily pregnant animals and animals under stress from adverse weather conditions, poor nutrition, penning, handling etc.

Animals must not be treated within a period of 14 days before or after treatment with organophosphorus compounds.Veterinary advice should be sought on appropriate dosing programmes and stock management, to achieve adequate parasite control, and to reduce the likelihood of anthelmintic resistance developing.

Veterinary advice should be sought if the product does not achieve the desired clinical effect since other diseases, nutritional disturbances or anthelmintic resistance might be involved.

In cases of lungworm infections, coughing may persist for a considerable time following successful treatment with Levacide 3% Drench. This is due to tissue damage caused by parasites.

After treatment, animals should be moved to clean pasture in order to prevent re-infection.

Levamisole activity is not affected by benzimidazole resistance.

Care should be taken to avoid the following practices because they increase the risk of development or resistance and could ultimately result in ineffective therapy:

Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device.

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Resistance to levamisole has been reported in Teladorsagia, Cooperia and Trichostrongylus species in sheep in a number of countries, including the EU. There are reports of resistance in Haemonchus in sheep outside the EU. Resistance to levamisole has been reported in Teladorsagia species in cattle in developed countries such as New Zealand. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of
nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

Pharmaceutical Precautions


Do not eat, drink or smoke when using this product. Wash splashes from eyes and skin immediately. Remove any contaminated clothing immediately. Wash hands and exposed skin after handling this product, and before meals.

Levamisole can cause idiosyncratic reactions and serious blood disorders in a very small number of people. If symptoms such as dizziness, nausea, vomiting or abdominal discomfort are experienced when using this product, or sore mouth, throat or fever occur shortly afterwards, then medical advice should be sought immediately.

Do not store above 25ºC. Protect from light.
Keep container in outer carton.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

PRODUCT SAFETY DATA SHEET

1. IDENTIFICATION OF SUBSTANCE / PREPARATION AND OF COMPANY / UNDERTAKING
Product Name Levacide 3% Drench
Supplier Norbrook Laboratories Ltd,
Station Works, Newry, Co.Down,
N.Ireland, BT35 6JP.
Telephone No. +44 (0) 28 3026 4435
Fax No. +44 (0) 28 3026 1721
E-Mail: enquiries@norbrook.co.uk.
Emergency Telephone +44 (0) 28 3026 4435
2. HAZARDS IDENTIFICATION
Physical and Chemical Hazards : Not classified as dangerous under EEC Directives 67/548/EEC,
88/379/EEC or 99/45/EC.
Environmental Hazards : None known
Adverse Human Health Effects : Levamisole can cause idiosyncratic reactions and serious blood
disorders in a very small number of people. Medical advice
should be sought quickly.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Substance/Preparation : Preparation
Active Ingredients : Levamisole
Description : Anthelmintic ( Chemical Group 2-LM )
Chemical Family : Imidazothiazole
4. FIRST AID MEASURES
Inhalation : Remove to fresh air. If any signs or symptoms occur or persist seek medical advice.
Skin Contact : Wash thoroughly with soap and water. Remove contaminated clothing and wash before
reuse.
Eyes Contact : Immediately flush eyes with copious amounts of water for at least 15 minutes. If irritation
persists, seek medical attention.
Ingestion : Do not induce vomiting. Seek medical attention.
5. FIRE FIGHTING MEASURES
Extinguishing media: Use carbon dioxide, dry chemical or alcohol-resistant foam spray extinguishers.
Use water spray to cool fire-exposed containers. A fine water mist may be used
to smother or to disperse vapours.

Fire and explosion hazards: None.

6. ACCIDENTAL RELEASE MEASURES
Personal Precautions : Eliminate all ignition sources. Prevent skin and eye contact.
Environmental Precautions : Keep away from drains, surface-water, ground-water and soil.
Method for Clean-up : Absorb small spills on spill pillows, sand, sawdust or other suitable absorbing
material.
7. HANDLING AND STORAGE
Handling : Avoid contact with eyes, skin or clothing. Do not breathe vapours or mist. Do not ingest.
Do not smoke or eat while handling the product. Wash thoroughly after handling. The
containers should be stored in their original boxes when not in use.
Storage : Store in closed containers in a cool, dry, well-ventilated area away from oxidisers, heat,
sparks and open flame. Protect containers from physical damage and light.
Keep container closed when not in use. Before opening large containers, release any
pressure build-up by loosening closure slowly. Do not transfer contents to unlabelled
containers. Do not store in aluminium containers. Use only with adequate ventilation.
Keep out of reach of children.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Component - Occupational Exposure Standard
Levamisole Not Established
For pure levamisole :
LD50 ( Oral, mouse ) 223 mg/kg
LD50 ( Oral, rat ) 180 mg/kg
Protective Equipment : Wear vinyl, nitrile or rubber gloves, a waterproof bib-apron and suitable eye
protection when applying the product.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form : Liquid
Colour : Clear, yellow
Odour : None.
10. STABILITY AND REACTIVITY
Stability : Stable under normal temperatures and pressures.
Conditions to avoid : None known
Materials to avoid : None known
11. TOXICOLOGICAL INFORMATION
Exposure Effects ( Acute )

Eye Contact : Direct contact of the solution with eyes can cause irritation.
Skin Contact : Prolonged or repeated contact with Levacide 3% Drench may cause irritation
and/or drying and cracking of the skin.
Inhalation : Vapours of Levacide 3% Drench may cause mild irritation of the nose and throat.
Ingestion : Oral toxicity of the Levacide 3% Drench solution is low.
Exposure Effects ( Chronic )
Unknown for the product mixture. When this product is used according to the
directions, prolonged exposure of man is not expected. Both its mutagenicity
and its teratogenicity are not known.
12. ECOLOGICAL INFORMATION
Data on the ecological implications for Levacide 3% Drench is not yet available.
13. DISPOSAL CONSIDERATIONS
Product/Residues : Do not discharge the product material into surface or waste water. For
disposal, use an incinerator licensed for chemical waste.
Package : Dispose of waste containers using regular disposal methods in accordance
with local and national environmental regulations.
14. TRANSPORT INFORMATION
Land, Sea & Air Transport
ADR/RID, IMO/IMDG, IATA/ICAO, UN No. : Not applicable
15. REGULATORY INFORMATION
Labelling Information : None
Safety phrases : S2 Keep out of reach of children
S7 Keep container tightly closed
16. OTHER INFORMATION
Vm : 2000/4054 For Animal Treatment Only
ML : 2000/01
Revision Date : 14/05/10
Revision No : 06
Printing Date : 09/07/2010
Suppliers data sheets and various chemicals and pharmaceuticals databases were used to compile this sheet.

The information contained in this PSDS is believed to be accurate and represents the best information available at the time of preparation. However Norbrook Laboratories Limited makes no warranty, express or implied, with respect to such information and assumes no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes, and Norbrook Laboratories Limited will not be held liable for any damage resulting from the handling of or contact with the above Product.

7.5% Low Volume Drench

Presentation

A clear yellow oral solution, containing:
Levamisole Hydrochloride 7.5% w/v

Uses

Levacide Low Volume is a broad spectrum anthelmintic for use in the treatment and control of nematode infections in cattle and sheep. It should be used in cases of parasitic gastroenteritis and lungworm disease caused by mature and developing immature forms of those organisms sensitive to treatment with levamisole hydrochloride.

Lungworms: Dictyocaulus spp.

Gastro-intestinal worms: Trichostrongylus spp., Cooperia spp., Ostertagia spp. (except inhibited Ostertagia larvae in cattle), Haemonchus spp., Nematodirus spp., Bunostomum spp., Oesophagostomum spp., Chabertia spp.

Dosage & Administration

Levacide Low Volume should be administered as an oral drench. Dosing must be carried out accurately using a dosing gun system at a rate of 7.5 mg levamisole hydrochloride/kg bodyweight.

Withdrawal Period

Animals must not be slaughtered for human consumption during treatment.

Cattle may be slaughtered for human consumption only after 14 days from the last treatment.

Sheep may be slaughtered for human consumption only after 21 days from the last treatment.
This product must not be used in cattle and sheep producing milk for human consumption.

Contraindictions, Warnings etc

Levacide Low Volume is safe for use in cattle and sheep at the recommended dosages. However, if the recommended dosages are exceeded, animals may exhibit signs of impaired motor functions such as muscle tremors, head shaking and increased salivation which are of a temporary nature.

To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.

Levacide Low Volume may be administered to pregnant or lactating animals. However, care should be taken when treating heavily pregnant animals and animals under stress from adverse weather conditions, poor nutrition, penning, handling etc.

Animals must not be treated within a period of 14 days before or after treatment with organophosphorus compounds. Veterinary advice should be sought on appropriate dosing programmes and stock management, to achieve adequate parasite control, and to reduce the likelihood of anthelmintic resistance developing.

Veterinary advice should be sought if the product does not achieve the desired clinical effect since other diseases, nutritional disturbances or anthelmintic resistance might be involved.

In cases of lungworm infections, coughing may persist for a considerable time following successful treatment with Levacide Low Volume. This is due to tissue damage caused by the parasites.

After treatment, animals should be moved to clean pasture in order to prevent re-infection.

Levamisole activity is not affected by benzimidazole resistance.

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:

Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device.

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Resistance to levamisole has been reported in Teladorsagia, Cooperia and Trichostrongylus species in sheep in a number of countries, including the EU. There are reports of resistance in Haemonchus in sheep outside the EU. Resistance to levamisole has been reported in Teladorsagia species in cattle in developed countries such as New Zealand. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

Operator Warnings:
Do not eat, drink or smoke when using this product. Wash splashes from eyes and skin immediately. If irritation persists seeks medical advice. Remove any contaminated clothing immediately. Wash hands and exposed skin after handling this product, and before meals.

Levamisole can cause idiosyncratic reactions and serious blood disorders in a very small number of people. If symptoms such as dizziness, nausea, vomiting or abdominal discomfort are experienced when using this product, or sore mouth, throat or fever occur shortly afterwards, then medical advice should be sought immediately.

Pharmaceutical Precautions


Do not store above 25ºC. Protect from light.
Keep container in outer carton.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

PRODUCT SAFETY DATA SHEET

1. IDENTIFICATION OF SUBSTANCE / PREPARATION AND OF COMPANY / UNDERTAKING
Product Name Levacide Low-Volume
Supplier Norbrook Laboratories Ltd,
Station Works, Newry, Co.Down,
N.Ireland, BT35 6JP.
Telephone No. +44 (0) 28 3026 4435
Fax No. +44 (0) 28 3026 1721
E-Mail: enquiries@norbrook.co.uk.
Emergency Telephone +44 (0) 28 3026 4435
2. HAZARDS IDENTIFICATION
Physical and Chemical Hazards : Not classified as dangerous under EEC Directives 67/548/EEC,
88/379/EEC or 99/45/EC.
Environmental Hazards : None known
Adverse Human Health Effects : Levamisole can cause idiosyncratic reactions and serious blood
disorders in a very small number of people. Medical advice
should be sought quickly.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Substance/Preparation : Preparation
Active Ingredients : Levamisole
Description : Anthelmintic ( Chemical Group 2-LM )
Chemical Family : Imidazothiazole
4. FIRST AID MEASURES
Inhalation : Remove to fresh air. If any signs or symptoms occur or persist seek medical advice.
Skin Contact : Wash thoroughly with soap and water. Remove contaminated clothing and wash before
reuse.
Eyes Contact : Immediately flush eyes with copious amounts of water for at least 15 minutes. If irritation
persists, seek medical attention.
Ingestion : Do not induce vomiting. Seek medical attention.
5. FIRE FIGHTING MEASURES
Extinguishing media: Use carbon dioxide, dry chemical or alcohol-resistant foam spray extinguishers.
Use water spray to cool fire-exposed containers. A fine water mist may be used
to smother or to disperse vapours.
02000/4081 – LEVACIDE LOW-VOLUME REVISION DATE: 14/05/10
2/4
Fire and explosion hazards: None.
6. ACCIDENTAL RELEASE MEASURES
Personal Precautions : Eliminate all ignition sources. Prevent skin and eye contact.
Environmental Precautions : Keep away from drains, surface-water, ground-water and soil.
Method for Clean-up : Absorb small spills on spill pillows, sand, sawdust or other suitable absorbing
material.
7. HANDLING AND STORAGE
Handling : Avoid contact with eyes, skin or clothing. Do not breathe vapours or mist. Do not ingest.
Do not smoke or eat while handling the product. Wash thoroughly after handling. The
containers should be stored in their original boxes when not in use.
Storage : Store in closed containers in a cool, dry, well-ventilated area away from oxidisers, heat,
sparks and open flame. Protect containers from physical damage and light.
Keep container closed when not in use. Before opening large containers, release any
pressure build-up by loosening closure slowly. Do not transfer contents to unlabelled
containers. Do not store in aluminium containers. Use only with adequate ventilation.
Keep out of reach of children.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Component - Occupational Exposure Standard
Levamisole Not Established
For pure levamisole :
LD50 ( Oral, mouse ) 223 mg/kg
LD50 ( Oral, rat ) 180 mg/kg
Protective Equipment : Wear vinyl, nitrile or rubber gloves, a waterproof bib-apron and suitable eye
protection when applying the product.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form : Liquid
Colour : Clear, yellow
Odour : None.
10. STABILITY AND REACTIVITY
Stability : Stable under normal temperatures and pressures.
Conditions to avoid : None known
Materials to avoid : None known
11. TOXICOLOGICAL INFORMATION
Exposure Effects ( Acute )
02000/4081 – LEVACIDE LOW-VOLUME REVISION DATE: 14/05/10
3/4
Eye Contact : Direct contact of the solution with eyes can cause irritation.
Skin Contact : Prolonged or repeated contact with Levacide Low-Volume may cause irritation
and/or drying and cracking of the skin.
Inhalation : Vapours of Levacide Low-Volume may cause mild irritation of the nose and
throat.
Ingestion : Oral toxicity of the Levacide Low-Volume solution is low.
Exposure Effects ( Chronic )
Unknown for the product mixture. When this product is used according to the
directions, prolonged exposure of man is not expected. Both its mutagenicity
and its teratogenicity are not known.
12. ECOLOGICAL INFORMATION
Data on the ecological implications for Levacide Low-Volume is not yet available.
13. DISPOSAL CONSIDERATIONS
Product/Residues : Do not discharge the product material into surface or waste water. For
disposal, use an incinerator licensed for chemical waste.
Package : Dispose of waste containers using regular disposal methods in accordance
with local and national environmental regulations.
14. TRANSPORT INFORMATION
Land, Sea & Air Transport
ADR/RID, IMO/IMDG, IATA/ICAO, UN No. : Not applicable
15. REGULATORY INFORMATION
Labelling Information : None
Safety phrases : S2 Keep out of reach of children
S7 Keep container tightly closed
16. OTHER INFORMATION
Vm : 2000/4081 For Animal Treatment Only
ML : 2000/01
Revision Date : 14/05/10
Revision No : 06
Printing Date : 09/07/2010
Suppliers data sheets and various chemicals and pharmaceuticals databases were used to compile this sheet.

The information contained in this PSDS is believed to be accurate and represents the best information available at the time of preparation. However Norbrook Laboratories Limited makes no warranty, express or implied, with respect to such information and assumes no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes, and Norbrook Laboratories Limited will not be held liable for any damage resulting from the handling of or contact with the above Product.

Pour On

Presentation

Levacide Pour-On is a blue solution for external pour-on transcutaneous administration containing levamisole 200 mg/ml.

Uses

Levacide Pour-On is a broad spectrum anthelmintic indicated for external use in cattle in the treatment and control of nematode infections such as parasitic gastro-enteritis and lungworm disease caused by mature and developing immature gastro-intestinal and pulmonary nematodes.

Lungworms:
Dictyocaulus viviparus

Gastrointestinal Roundworms:
Trichostrongylus spp
Cooperia spp
Ostertagia ostertagi (except inhibited O. ostertagi larvae)
Haemonchus spp
Nematodirus spp
Bunostomum spp
Oesophagostomum spp

Dosage & Administration

Levacide Pour-On is indicated for external pour-on transcutaneous administration to cattle.

The recommended dose rate is 10 mg levamisole per kg bodyweight, equivalent to 2.5 ml per 50 kg bodyweight.

The bodyweight of animals should be assessed as accurately as possible before calculating the dosage.

Bodyweight Dose
Up to 50 kg (1 cwt) 2.5 ml
51-100 kg (1-2 cwt) 5 ml
101-150 kg (2-3 cwt) 7.5 ml
151-200 kg (3-4 cwt) 10 ml
201-250 kg (4-5 cwt) 12.5 ml
251-300 kg (5-6 cwt) 15 ml
301-350 kg (6-7 cwt) 17.5 ml

Above 350 kg give a further 2.5 ml for each additional 50 kg bodyweight.

For external administration only: Pour on from the calibrated dispenser or using a standard dosing gun. Apply along the flattest part of the backline at the rate of 10 mg levamisole/kg bodyweight, equivalent to 2.5 ml per 50 kg bodyweight.

Dosing schedule: Dose all young cattle in early summer and if possible move onto clean pasture. Seek veterinary advice on subsequent retreatment.

Treatment of lungworm infection: Cattle should be dosed on the first signs of lungworm infestation; (rapid breathing or coughing). Seek veterinary advice on subsequent retreatment.

Shake well before use.

Equipment should be thoroughly cleaned before and after dosing.

APPLICATION:
For the 500 ml twin neck dispenser, simply squeeze the bottle to allow the appropriate amount of liquid into the calibrated dispenser. The 2.5 L Jerry-can should be used in conjunction with a standard dosing gun.

Withdrawal Period

Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 28 days from the last treatment. Do not use in animals producing milk for human consumption.

Contraindictions, Warnings etc

For external use only.

Do not treat animals when wet, and where possible, prevent treated animals from being exposed to rain for one hour post treatment.

Levacide Pour-On is safe for use in cattle at the recommended dosage. In cases of overdosage, hyperaesthesia, tremor and occasionally diarrhoea may occur.

Cattle must not be treated within a period of 14 days before or after treatment with organophosphorus compounds.

Do not exceed the stated dose.

The bodyweight of animals should be assessed as accurately as possible before calculating the dose. As with other anthelmintics, veterinary advice should be sought:

(a) on appropriate dosing programmes and stock management to achieve adequate parasite control, and to reduce the likelihood of anthelmintic resistance developing;

(b) if the product does not achieve the desired clinical effect, as other diseases, nutritional disturbances or anthelmintic resistance may be present.

Levacide Pour-On may be administered to pregnant or lactating animals but care should be taken when treating heavily pregnant animals or animals suffering stress from adverse weather conditions, poor nutrition, penning, handling etc.

Side effects:
At the recommended dose rates, animals should not show any adverse effects. However, local skin irritation at the application site may be observed occasionally, characterised by subcutaneous oedema. Severe cases may show signs of epidermal flaking for which symptomatic treatment is recommended.

Pharmaceutical Precautions

Do not store above 25ºC. Store out of reach of children. Do not freeze. Protect from light.
Store tightly closed in original container. Following withdrawal of the first dose, use the product within 6 months. Discard unused material.

Further Information


Levamisole belongs to the Imidazothiazole (2-LM) class of anthelmintics.

In cases of lungworm infection coughing may persist for a considerable time following successful treatment. This is due to tissue damage caused by the parasites.

After dosing animals should be moved to clean pasture. If this is not possible retreatment at regular intervals may be required to prevent re-infection.

PRODUCT SAFETY DATA SHEET

1. IDENTIFICATION OF SUBSTANCE / PREPARATION AND OF COMPANY / UNDERTAKING
Product Name Levacide Pour-On
Supplier Norbrook Laboratories Ltd,
Station Works, Newry, Co.Down,
N.Ireland, BT35 6JP.
Telephone No. +44 (0) 28 3026 4435
Fax No. +44 (0) 28 3026 1721
E-Mail: enquiries@norbrook.co.uk.
Emergency Telephone +44 (0) 28 3026 4435
2. HAZARDS IDENTIFICATION
Physical and Chemical Hazards : Not classified as dangerous under EEC Directives 67/548/EEC,
88/379/EEC or 99/45/EC.
Environmental Hazards : None known
Adverse Human Health Effects : Levamisole can cause idiosyncratic reactions and serious blood
disorders in a very small number of people. Medical advice
should be sought quickly.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Substance/Preparation : Preparation
Active Ingredients : Levamisole
Description : Anthelmintic ( Chemical Group 2-LM )
Chemical Family : Imidazothiazole
4. FIRST AID MEASURES
Inhalation : Remove to fresh air. If any signs or symptoms occur or persist seek medical advice.
Skin Contact : Wash thoroughly with soap and water. Remove contaminated clothing and wash before
reuse.
Eyes Contact : Immediately flush eyes with copious amounts of water for at least 15 minutes. If irritation
persists, seek medical attention.
Ingestion : Do not induce vomiting. Seek medical attention.
5. FIRE FIGHTING MEASURES
Extinguishing media: Use carbon dioxide, dry chemical or alcohol-resistant foam spray extinguishers.
Use water spray to cool fire-exposed containers. A fine water mist may be used
to smother or to disperse vapours.

Fire and explosion hazards: Isopropyl alcohol, as a constituent, will not burn or ignite under normal usage
but is a dangerous fire hazard and a moderate explosion hazard when exposed
to heat, flames or oxidisers. Vapours are heavier than air and may travel a
considerable distance to an ignition source and flashback.
6. ACCIDENTAL RELEASE MEASURES
Personal Precautions : Eliminate all ignition sources. Prevent skin and eye contact.
Environmental Precautions : Keep away from drains, surface-water, ground-water and soil.
Method for Clean-up : Absorb small spills on spill pillows, sand, sawdust or other suitable absorbing
material.
7. HANDLING AND STORAGE
Handling : Avoid contact with eyes, skin or clothing. Do not breathe vapours or mist. Do not ingest.
Do not smoke or eat while handling the product. Wash thoroughly after handling. The
containers should be stored in their original boxes when not in use.
Storage : Store in closed containers in a cool, dry, well-ventilated area away from oxidisers, heat,
sparks and open flame. Protect containers from physical damage and light.
Keep container closed when not in use. Before opening large containers, release any
pressure build-up by loosening closure slowly. Do not transfer contents to unlabelled
containers. Do not store in aluminium containers. Use only with adequate ventilation.
Keep out of reach of children.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Component - Occupational Exposure Standard
Levamisole Not Established
Isopropyl Alcohol OES ( 8hr TWA ) 400 ppm ( 980 mg/m3 )
For pure levamisole :
LD50 ( Oral, mouse ) 223 mg/kg
LD50 ( Oral, rat ) 180 mg/kg
Protective Equipment : Wear vinyl, nitrile or rubber gloves, a waterproof bib-apron and suitable eye
protection when applying the product.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form : Liquid
Colour : Blue
Odour : Characteristic smell of isopropyl alcohol. Do not test for odour.
Flash point : 14°C
10. STABILITY AND REACTIVITY
Stability : Stable under normal temperatures and pressures.
Conditions to avoid : None known

Materials to avoid : Isopropyl alcohol is incompatible with acetaldehyde, chlorine, ethylene oxide,
hypochlorous acid, isocyanates, phosgene, oleum, perchloric acid and strong
oxidising agents.
11. TOXICOLOGICAL INFORMATION
Exposure Effects ( Acute )
Eye Contact : Direct contact of the solution with eyes can cause irritation.
Skin Contact : Prolonged or repeated contact with Levacide Pour-On may cause irritation
and/or drying and cracking of the skin.
Inhalation : Vapours of isopropyl alcohol may cause mild irritation of the nose and throat.
Prolonged exposures to isopropyl alcohol above the OES may cause nausea,
headache and mild narcosis.
Ingestion : Oral toxicity of the Levacide Pour-On solution is low. Ingesting a large amount
of isopropyl alcohol will cause burning of the gastrointestinal tract, nausea,
vomiting and CNS depression.
Exposure Effects ( Chronic )
Unknown for the product mixture. When this product is used according to the
directions, prolonged exposure of man is not expected. Both its mutagenicity
and its teratogenicity are not known.
12. ECOLOGICAL INFORMATION
Data on the ecological implications for Levacide Pour-On is not yet available.
13. DISPOSAL CONSIDERATIONS
Product/Residues : Do not discharge the product material into surface or waste water. For
disposal, use an incinerator licensed for chemical waste.
Package : Dispose of waste containers using regular disposal methods in accordance
with local and national environmental regulations.
14. TRANSPORT INFORMATION
Land Transport, Sea Transport, Air Transport
ADR / RID IMO / IMDG IATA / ICAO
UN Number : 1219
Proper Shipping Name Isopropanol (Isopropyl Alcohol)
Class : 3
Packing Group : II
Hazchem Code : 2(Y)E
15. REGULATORY INFORMATION
Labelling Information

Risk phrases : R 11 Highly flammable
Safety phrases : S2 Keep out of reach of children
S7 Keep container tightly closed
S16 Keep away from sources of ignition - No Smoking
16. OTHER INFORMATION
ML : 2000/01 For Animal Treatment Only
Vm : 2000/4138
Revision Date : 14/05/10
Revision No : 06
Printing Date : 09/07/2010
Suppliers data sheets and various chemicals and pharmaceuticals databases were used to compile this sheet.

The information contained in this PSDS is believed to be accurate and represents the best information available at the time of preparation. However Norbrook Laboratories Limited makes no warranty, express or implied, with respect to such information and assumes no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes, and Norbrook Laboratories Limited will not be held liable for any damage resulting from the handling of or contact with the above Product.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Freephone*: 0800 084 2608
  • Mon - Fri: 8:30am - 6:00pm
  • Sat: 9:00am - 1:00pm
  • Email: support@viovet.co.uk

All prices include VAT where applicable. *The freephone number is free from most UK landlines only, mobiles are usually charged so we'd recommend calling our landline from your mobile or internationally.

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