Karidox

Karidox contains the antibiotic doxycycine and is intended to be used in chickens and pigs, particularly against respiratory infections.

Presentation
A clear, dense, brownish-yellow solution containing 100 mg doxycycline, asdoxycycline hyclate, per ml.

Uses
In chickens, prevention and treatment of chronic respiratory disease (CRD) andmycoplasmosis caused by microorganisms sensitive to doxycycline.In pigs,prevention of clinical respiratory disease due toPasteurella multocidaandMycoplasma hyopneumoniaesensitive to doxycycline. The presence of the disease inthe herd should be established before treatment.

Instructions for use
Karidox is to be administered in drinking water.For chickens, give 10-20 mg of doxycycline / kg live weight / day for 3-5 days (i.e. 0.5-1.0 ml of product / litre ofdrinking water / day).For pigs, give 10mg of doxycycline / kg b.w. / day for 5 days(i.e. 1 ml of product / 10 kg b.w. / day).To ensure the correct dosage and avoid under dosing, live weight should be determined as accurately as possible. The consumption of medicated water depends on the clinical condition of the animals. In order to achieve the correct dosage, the concentration of doxycycline has to be adjusted accordingly. Medicated water should be the only water available.The medicated water may be used only for 24 hours and should be made up freshly every day. If no improvement in clinical signs is seen within the recommended duration of treatment, the diagnosis should be reviewed and the treatment changed.

Contra-indications and warnings
Do not use Karidox in animals hypersensitive to tetracyclines, in animals with hepatic dysfunction or for laying hens.Allergic and photosensitivity reactions can occur.Intestinal flora may be affected if treatment is very prolonged, and this may result in digestive disturbance. Do not administer Karidox to laying birds from four weeks before the start of lay and during lay. It should not be used during pregnancy orlactation.Absorption of doxycycline may be reduced by high concentrations of calcium, iron, magnesium or aluminium in the diet. Do not administer with antacids,kaolin or iron preparations.Do not administer together with bactericidal antibiotics.The solubility of the product depends on acidity and will it precipitate if mixed in analkaline solution. Do not administer with milk replacers.Special precautions for use in animals. Avoid administration in oxidized drinking equipment. Resistance against doxycycline may vary, so the use of this product should be based on culture and sensitivity of micro-organisms from diseased cases on the farm or on recent experience on the farm.Special precautions to be taken by the person administering Karidox to animals Do not handle the product if you are hypersensitive to tetracyclines.Wear gloves,overalls and approved safety glasses.This product is acid and likely to be irritant.Avoid its contact with the skin and eyes. In case of contact with skin, rinse immediately with plenty of water. In case of contact with eyes, rinse immediately