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For the vaccination of sheep as an aid to the prevention and treatment of footrot. Refrigerated Product. POM-VPS.
Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication.
Company name: MSD Animal Health
Address: Walton Manor
Telephone: 01908 685685 (Customer Support Centre)
Fax: 01908 685555
Email: [email protected]
Emulsion for injection containing per dose (1 ml) 10 µg pili of each of Dichelobacter nodosus serotypes A, B1, B2, C, D, E, F, G and H and 5 x 108 cells of D. nodosus serotype I. 60% Light mineral oil NF and 4.5% Manide oleate are added as adjuvants. 0.015 % Thiomersal is added as a preservative.
For the active immunisation of sheep as an aid to the prevention of footrot and reduction of lesions of footrot caused by serotypes of D. nodosus.
Dose: 1 ml.
Initial Course: Two doses, 6 weeks apart by subcutaneous injection. The site for injection is on the side of the neck 2-3 inches behind the ear.
Thoroughly shake the vaccine before use.
As the vaccine contains an oil adjuvant it is rather viscous. It will aid administration in cold weather if the vaccine is gently warmed by immersion in warm water (not hot) for 3-4 minutes before use.
Syringes and needles should be sterilised before use and the injection made through an area of clean, dry skin, taking strict precautions against contamination in order to reduce the possibility of abscess formation.
These should be tailored to meet individual flock requirements which will vary from season to season according to the actual or likely incidence of footrot.
Wherever possible ‘whole flock’ vaccination programmes should be adopted. By this means disease incidence in the flock will decline and subsequent disease risk from the environment will be greatly reduced.
Commence vaccination with a single dose of vaccine. Further doses of vaccine will be required according to the flock disease status and/or the climatic conditions. If, after 4-6 weeks significant levels of disease remain in the flock or climatic conditions conducive to footrot persist, administer a further dose. Otherwise delay this dose until conditions favour re-emergence of the disease. Subsequent doses should also be administered according to prevailing conditions. Thus, with severe and constant disease challenge, revaccination may be necessary at 4-5 monthly intervals; conversely under favourable conditions revaccination may be delayed until the incidence of disease challenge increases or climatic conditions worsen.
It should be noted that these adverse conditions tend to occur in the UK between March and May and between October and December thus, vaccination should normally be completed shortly before these periods if problems are anticipated.
A single dose of vaccine should be given to the flock immediately the disease becomes apparent. For maximum effect, treatment with Footvax should be combined with the use of a footbath, hoof-paring and antibiotic treatment.
Revaccination should be as stated in the prevention programme, which should then be continued on the farm as the key element of the overall flock foot care programme.
Can be used during pregnancy.
Do not vaccinate sheep within 6–8 weeks of shearing. Do not use in lactating dairy sheep. Do not vaccinate ewes in the period of 4 weeks before lambing to 4 weeks after lambing.
Sheep destined for show or sale should not be vaccinated within the previous 6 months because of the occurrence of a well defined, inactive lump at the site of injection.
The vaccine may cause a reaction at the site of injection. This may range from a slight swelling from about 24 hours after injection, to a well-defined lump of about 3 cm diameter 8 days after injection. These may further increase in size to 5 or even 8 cm diameter but these swellings generally remain inactive and may resolve completely within 4-6 weeks. Frequently swellings persist for at least ten weeks. Occasionally, however, these swellings may be large, painful and unsightly, with the formation of abscesses which may burst and discharge, particularly if any contaminating skin bacteria are introduced at the time of injection. Even so, partial or complete resolution within ten weeks of inoculation can be expected. Reactions to second doses develop more slowly but the formation of necrotic lesions is rare. Occasionally abscesses may be noted on macroscopic examination of injection sites. Subcutaneous necrosis and inflammation may be noted on microscopic examination of injection sites.
On rare occasions variable incidence of generalised lameness has been reported in vaccinated sheep. This is thought to be due to a local immunological reaction in the feet and is transitory in nature, occurring within 24 hours of vaccination and normally persisting for no more than 48 hours. Treatment is seldom necessary.
Occasional hypersensitivity reactions may occur. In such cases an appropriate dose of adrenalin and/or antihistamines should be administered without delay.
When the vaccine is given at twice the recommended dose a reaction similar to that described above should be expected. In some cases skin lesions with overt pus accumulation or slight necrosis develop. This necrotic skin lesion and pus accumulation occurs less frequently following a second injection. There are no adverse clinical signs in animals following treatment with 2x dose. There is no specific antidote.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except those mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.
Do not mix with any other veterinary medicinal products.
To the user: This product contains mineral oil. Accidental injection/self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.
If you are accidentally injected with this product, seek prompt medical advice even if only a very small amount is injected and take the package leaflet with you.
If pain persists for more than 12 hours after medical examination, seek medical advice again.
To the doctor: This product contains mineral oil. Even if small amounts have been injected, accidental injection with this product can cause intense swelling, which may, for example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.
For animal treatment only. Keep out of reach and sight of children.
Store and transport refrigerated (2°C to 8°C). Protect from light. Do not freeze.
Once opened use immediately.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with the local requirements.
Carton with one bottle containing 20 ml, 50 ml and 250 ml.
All prices include VAT where applicable.
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