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FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats

FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats
Cat » 1 Pipette Cat » 1 Pipette Cat » 1 Pipette
Dog Extra Large (40-60kg) » 1 Pipette Dog Extra Large (40-60kg) » 1 Pipette Dog Extra Large (40-60kg) » 1 Pipette
Dog Large (20-40kg) » 1 Pipette Dog Large (20-40kg) » 1 Pipette Dog Large (20-40kg) » 1 Pipette
Dog Medium (10-20kg) » 1 Pipette Dog Medium (10-20kg) » 1 Pipette Dog Medium (10-20kg) » 1 Pipette
Dog Small (2-10kg) » 1 Pipette Dog Small (2-10kg) » 1 Pipette Dog Small (2-10kg) » 1 Pipette

Images are for illustration purposes only. Packaging may change from time to time and images on our website may or may not be updated.

  • Cat » 1 Pipette £5.86
  • Cat » 3 Pipettes £12.98
  • Cat » 6 Pipettes £20.79
  • Dog Extra Large (40-60kg) » 1 Pipette £8.58
  • Dog Extra Large (40-60kg) » 3 Pipettes £26.75
  • Dog Extra Large (40-60kg) » 6 Pipettes £46.34
  • Dog Large (20-40kg) » 1 Pipette £7.34
  • Dog Large (20-40kg) » 3 Pipettes £22.18
  • Dog Large (20-40kg) » 6 Pipettes £30.98
  • Dog Medium (10-20kg) » 1 Pipette £6.73
  • Dog Medium (10-20kg) » 3 Pipettes £23.99
  • Dog Medium (10-20kg) » 6 Pipettes £32.66
  • Dog Small (2-10kg) » 1 Pipette £6.17
  • Dog Small (2-10kg) » 3 Pipettes £18.62
  • Dog Small (2-10kg) » 6 Pipettes £30.29

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FRONTLINE Spot On is the clear market leader for flea and tick treatment for dogs and cats. Easy to use, safe and effective, its introduction revolutionised flea treatment around the world. Many copy type products have appeared, but Frontline Spot-On for dogs and cats remains well ahead of its rivals.

It is supplied in packets of 3 or 6 single use pipettes. The contents of one pipette are applied to the skin at the back of the neck once a month to provide valuable and lasting cover against fleas and ticks, as well as the other health problems they can sometimes cause.

In addition to this flea treatment you may require an additional household spray to combat fleas which may not have yet hatched or dormant fleas in and around the house. Please click here to see the range of household sprays available.

Please take care not to let the product come into contact with varnished or other household surfaces. The alcohol carrier in the product may have adverse effects on these surfaces. Allow the products to fully dry before allowing the animal contact with these surfaces and do not put used pipettes on them.

FRONTLINE Spot On Flea Treatment

The introduction of Frontline revolutionised the treatment of fleas and ticks on dogs and cats in this country and much of the world. It was originally only available as a spray. When a spot-on formulation came out, this just about swept away every other flea treatment on the market at that time. Since then many 'copy' type products have come onto the market. Some are inferior, some contain the exact same ingredient and can be presumed to be similar both in terms of safety and efficacy. Frontline is also available as a spray. In some circumstances this can be the best form of treatment, but it is more difficult to apply and is not available without prescription.

How does it work?

Frontline Spot-on is supplied in small plastic pipettes. A pipette is opened and the contents are tipped onto the dog or cat's skin at the top of the neck. From here the active ingredient (fipronil) spreads over the surface of the skin and binds to the surface of the skin and hair. Almost none of the drug is absorbed into the body, making it very safe to use. Within about 24 hours it will have spread over the entire body surface, killing fleas wherever they are. Because it binds to the surface it is alright to shampoo an animal, or for it to go swimming, and Frontline will still work. However this should not happen within the first 2 days, and then not more often than once per week, or the duration of effect might be reduced. Normally Frontline lasts for about a month on cats, and two months on dogs. After this length of time much of the treated skin/hair will have been shed and another dose has to be applied.

How effective is it?

Fleas which come into contact with Frontline will die after about 24 hours. This appears to be a reliable and consistent fact. Any fleas living on an animal will be dead within two days of Frontline being applied. However it is important to know that fleas spend much of their life not on the animal at all. This means that treating your cat or dog will not get rid of all the fleas. Many will be living in the pet's bedding, in carpets, or in any nooks and crannies they can find. Female fleas lay eggs as they wander through the fur. These eggs drop to the ground where they hatch and develop. This can happen very quickly in warm, muggy weather. But if it is cold (or very dry), they can remain dormant for a long time, becoming active when it warms up. These new fleas will jump onto your pets (or sometimes even you) when they develop. This is why people often discover a flea problem when they switch the central heating on in late autumn. Dormant fleas (in the form of pupae) are stimulated into activity by the warmth. Therefore if you are aware of fleas on your pets, you can be pretty sure that you are seeing a small fraction of the total population. (It is often claimed that there will be up to 100 fleas living in the environment of our pets, for every one found on a pet!) Therefore if fleas are being seen, it is very important to treat the whole house with an insecticide, to vacuum carpets frequently, and to wash any bedding if possible. If you are not seeing fleas, and are using Frontline as a precaution, then this is less important. The environmental infestation will not occur if your pets are treated with Frontline all the time. But if you let the fleas get a 'head start', then just treating the pets will be a slow way of getting rid of the entire flea population. As soon as you see fleas, it normally means there are lots, and you need to treat the house as well as the pets to get rid of them. If there is a very heavy flea burden in the environment before you start treating your pets, it can take quite a while to get rid of them all, even with a product as effective as Frontline. This does not mean there is any resistance developing, which seems not to be the case. It is just a feature of flea populations. It is always best to treat as a preventative, rather than waiting for a real problem to develop.

Does Frontline have any side effects?

Frontline is extremely safe when used on cats and dogs in the recommended way. Very little of the drug is absorbed into the body at all. Occasionally there will be a localised skin reaction at the site of application. This is more commonly seen on cats and is usually a small patch of inflamed skin with some hair loss. It normally clears up without treatment after a few weeks, but if this does occur, it might be best to avoid using Frontline Spot-on in future. There is some evidence that Frontline can be dangerous to rabbits, so avoid using Frontline on them.

The difference between FRONTLINE Spot On & FRONTLINE Combo?

  • Frontline Spot On
    • This contains one ingredient.
    • It coats the skin and hair after being applied and kills off fleas.
    • It persists on the coat even if the animal swims or is shampooed, as long as there is at least a 24 hour gap before and after applying the Frontline.
  • Frontline Combo (Prescription required)
    • This contains 2 ingredients.
    • The first one is exactly the same as in normal Spot-on.
    • The second one also coats the skin and coat, but does not kill fleas at all. Instead it sterilises fleas, so that they cannot breed.
    • The idea of it is that it persists longer on the coat than the killing ingredient.
    • Hence if people do not re-apply the frontline as often as they should, then the killing ingredient will no longer be effective (especially on animals at the top of the weight range of the product used). The other ingredient works for about twice as long as the main ingredient. The idea behind this is that if fleas cannot breed, you only get very small numbers of them and they are unlikely to be noticed or do any harm.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Delivery Information

Reviews (409)

Summary of Reviews for FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats

Overall 5
Ease Of Use
Value For Money
Absence Of Side Effects
385 out of 409 (94%) customers would recommend this product.
5 stars (318 reviews)
4 stars (59 reviews)
3 stars (8 reviews)
2 stars (5 reviews)
1 stars (19 reviews)

Only verified purchasers of this product can leave a review.

45 It works
Verified Purchase

By on 6 January 2020

It say what it does on the packet.

Customer recommends this product

55 Hassle free
Verified Purchase

By on 31 December 2019

Works fantastically. Had trouble buying elsewhere but so convenient here.

Customer recommends this product

45 Good for cats and dogs
Verified Purchase

By on 9 December 2019


Customer recommends this product

55 Frontline spot on
Verified Purchase

By on 30 October 2019

Very good product value for money

Customer recommends this product

45 Came quickly
Verified Purchase

By on 5 October 2019

It’s made a difference but still not got rid of the fleas on the cats I had to get flea collars as well

Customer recommends this product

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Q & A

Below are some recent questions we've received regarding FRONTLINE Spot On Flea & Tick Treatment Dogs & Cats, including answers from our team.

30 July 2018 at 11:49pm



Are there different pippette sizes depending upon the weight of cats?

  • VioVet Staff

Hello Nicola,

There is only one pipette available for cats as this particular treatment covers cats weighing between 1kg-8kg.

Hope this helps.

29 November 2016 at 11:34pm

Possible pregnant bitch

Marella smith

I believe my girl dog maybe a few days pregnant. Is front line safe to use on her if she is pregnate please. I don't want to put the pups at risk

  • VioVet Staff

Yes, Frontline is safe to use in breeding, pregnant and lactating bitches.

29 December 2015 at 1:27pm


Laura Lowe

  • VioVet customer since 2010
  • From: East Sussex, United Kingdom

Is frontline OK to use for puppies

  • VioVet Staff

Hi Laura, Frontline can be used on puppies over 8 weeks old and weighing over 2kg. I can see that Milo (4kg) is registered on your account, and if he is the puppy you wish to treat, you just need to wait another week and then he can be treated with a pipette of Frontline 2-10kg.

25 November 2015 at 5:17pm



  • VioVet customer since 2015
  • From: Staffordshire, United Kingdom

I brought frontline for my kitten who is 1.25kg but i just need to know if i use this every 4 weeks on him.??

  • VioVet Staff

Yes that is correct, you should use it every 4 weeks to maintain effective flea control.

24 November 2015 at 5:13pm

Just over 1kg kitten

Kirsty Sharratt

  • VioVet customer since 2015
  • From: Staffordshire, United Kingdom

I ordered frontline for my kitten who is 14 weeks and he is just weighing over 1kg, i had to purchase stonghold from the vets as he was too light for this before. As hes now just over 1kg is stonghold fine to use on him and do i use the whole pipet or half every 4 weeks.??

  • VioVet Staff

As long as your kitten is over 8 weeks of age and 1kg in bodyweight, you can use Frontline Spot-on.

For Stronghold (which does worms as well but needs a vet's prescription) there are different sizes available, though your vet might not sell all of them. The kitten size of Stronghold is safe to use once the kitten is over 6 weeks of age, regardless of bodyweight. A normal 6 week kitten is never over 1kg but this is not a problem in fact.

Frontline Spot-on is still a great product to use for routine flea and tick control, but you need to do something else as well for worm control. (Stronghold does not treat ticks, so if these are a concern in your area, you probably need Frontline for them anyway.)

2 November 2015 at 4:46am

Different package


  • VioVet customer since 2015
  • From: , Korea, Republic of

I'm currently in South Korea and bought a package at a local vet's office but it looks different from the image on this site. Do frontline packages vary according to the countries or continents they are exported to? If so, can I expect to have the same result when I buy Frontline on this site and at the local vet's office?
Thanks in advance.

  • VioVet Staff

Packaging does often vary depending on the country where it is marketed. As long as it is genuinely Frontline, manufactured by Merial, then it will be exactly the same product wherever you buy it from. The Frontline we sell is all genuine and is produced for sale in the UK. We are able to export it but we do not get hold of any different stock to do so, we simply export the UK product.

Obviously I have no idea if the product you bought locally is genuine, but if it cam from a veterinary premises I do not doubt it will be genuine. It just has local packaging.

20 August 2015 at 10:06am



Can this safely be used on greyhounds as I know greys can be sensitive to chemicals

  • VioVet Staff

Occasionally this product will cause a small sore patch on the skin where it is applied. This is unusual even in Greyhounds but with their thin skin it can certainly occur. Usually they are fine with it and all effective flea product can cause reactions of some sort occasionally. Frontline is extremely safe in other respects and so on balance it is probably a good product for you to use.

3 April 2015 at 4:35am

Super fleas

Gaynor Tomlin

  • VioVet customer since 2012
  • From: Limassol, Cyprus

Can you tell me what to do if fleas & ticks stop responding to frontline after using it on 3 small dogs for 5 years in cyprus with success

  • VioVet Staff

You could get a prescription for Advantix and use that for a while. Usually after a period of time, people find that Frontline will seem to start working again if you keep on using it every month. This is because the problem usually has some other cause and is not down to genuine resistance.

3 April 2015 at 4:25am

Something stronger


Hello I live in cyprus & have used frontline on my dogs for 5 years now, it seems the grease & ticks have grown used to it. Do you do something else for this predicament.

  • VioVet Staff

A good alternative for flea control would be Advantage, though this does not treat against ticks. Usually you find that Frontline will start working again in time, because this is not usually a genuine resistance problem. Whatever you do, keep treating every month until the problem is gone.

1 March 2015 at 11:45am

Pregnant bitch

Bobbie campbell

Is this safe to use on pregnant bitch

  • VioVet Staff

This product is regarded as very safe and should be fine to use on your bitch. It is a general rule to try and avoid any medication during the first 3 weeks of pregnancy in a bitch, but after that Frontline should be perfectly safe.