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Excenel Antibiotic Injection

Excenel Antibiotic Injection
Sterile Powder for Solution for Injection » 1g

  • Sterile Powder for Solution for Injection » 1g £26.49
  • Sterile Powder for Solution for Injection » 4g £78.49

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This product is sourced in the United Kingdom and is intended for use in the United Kindgom only.

Excenel is an antibiotic used to treat various serious disease in cattle and pigs, particularly including respiratory disease, uterine infections after giving birth and foot rot.

For full datasheet information, click on the product names below.

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Medication Datasheets

Sterile Powder for Solution for Injection » 1g

Excenel 50 mg/ml Sterile Powder for Solution for Injection


Vials containing a powder for solution for injection. Vials contain either 1 g or 4 g ceftiofur as the sterile, freeze-dried sodium salt. Ceftiofur sodium is a white to beige, amorphous powder requiring reconstitution with Water for Injection. Each ml of reconstituted solution contains ceftiofur sodium equivalent to 50 mg ceftiofur.


Excenel contains ceftiofur which is a beta-lactamase resistant, broad spectrum, bactericidal cephalosporin antibiotic. The product is indicated for:

Dosage and administration


1 g vial. Reconstitute by adding 20 ml Water for Injection.

4 g vial. Reconstitute by adding 80 ml Water for Injection.

For ease of reconstitution use an 18 gauge needle. Rapid addition of diluent will give best results.

Dosage: Cattle

1 mg/kg bodyweight. This is equivalent to 1 ml of the reconstituted solution per 50 kg bodyweight. For respiratory disease, the dose should be given once daily at 24 hour intervals for 3 to 5 days in total. For foul in the foot, the dose should be given once daily at 24 hour intervals for 3 days in total. As with all antibiotic therapy, treatment of this condition with Excenel should be instituted as early as possible in order to provide maximum clinical effect.


3 mg/kg bodyweight. This is equivalent to 1 ml of the reconstituted solution per 16 kg bodyweight. The dose should be given once daily at 24 hour intervals for 3 days in total.

If no response is seen within these periods, the diagnosis should be redetermined.


2 mg/kg bodyweight. This is equivalent to 2 ml of the reconstituted solution per 50 kg bodyweight. The dose should be given once daily at 24 hour intervals and continued for 48 hours after clinical signs have disappeared. A 10 day treatment period is usually adequate. A maximum of 10 ml solution should be administered per injection site. If no response is seen within 4–5 days, the diagnosis should be redetermined.


The intramuscular route only should be used in cattle, pigs and horses. In the pig, particular care must be taken to avoid injection into fat tissue. Normal aseptic injection techniques should be practiced.

Contra-indications, warnings, etc

The use of Excenel Sterile Powder is contra-indicated in animals previously found to be hypersensitive to ceftiofur.

Do not use in poultry (including eggs) due to the risk of spread of antimicrobial resistance to humans.

The use of the product may cause occasional local discomfort upon injection but this is a transient effect.

The administration of antimicrobials to horses under conditions of stress may be associated with acute diarrhoea which could be fatal. If acute diarrhoea is observed, discontinue use of this antimicrobial and initiate appropriate therapy.

Excenel Sterile Powder selects for resistant strains such as bacteria carrying extended spectrum betalactamases (ESBL) and may constitute a risk to human health if these strains disseminate to humans e.g. via food. For this reason, Excenel Sterile Powder should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly (refers to very acute cases when treatment must be initiated without bacteriological diagnosis) to first line treatment.

Official, national and regional antimicrobial policies should be taken into account when the product is used. Increased use, including use of the product deviating from the instructions given in the SPC, may increase the prevalence of such resistance. Whenever possible, Excenel Sterile Powder should only be used based on susceptibility testing.

Excenel Sterile Powder is intended for treatment of individual animals. Do not use for disease prevention or as a part of herd health programmes. Treatment of groups of animals should be strictly restricted to ongoing disease outbreaks according to the approved conditions of use.

Withdrawal period

Cattle: meat: 1 day.

Milk: zero hours.

Pigs: meat: 2 days.

Horses: Not for use in horses intended for human consumption.

Treated horses may never be slaughtered for human consumption.

The horse must have been declared as not intended for human consumption under national horse passport legislation.

Operator warnings

Care should be taken to avoid accidental self-injection. In the event of accidental self-injection, seek medical advice immediately.

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Handle this product with great care to avoid exposure taking all recommended precautions.

If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.

Wash hands after use.

Pharmaceutical precautions

Store unreconstituted product in a refrigerator (2°–8°C).

After reconstitution, product may be stored for 7 days at +2°C to +8°C, or for 12 hours when stored below 25°C.

Protect from light. The colour of the powder may vary from off-white to tan. The colour of the powder does not affect potency.

Any unused product or waste materials should be disposed with in accordance with national requirements.

For animal treatment only.

Keep out of reach and sight of children.

Legal category

Packaging quantities

Excenel Sterile Powder is supplied as 1 g vials or 4 g vials. Not all pack sizes may be marketed.

Further information

After recommended dose, therapeutic levels of ceftiofur are achieved within a few minutes and are maintained for at least 24 hours.

Marketing Authorisation Number

Vm 42058/4066

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.


Q & A

Below are some recent questions we've received regarding Excenel Antibiotic Injection, including answers from our team.

4 August 2015 at 12:24am

Excenel RTU


Can I give Excenel RTU to my farm dog to help with imfection?

  • Non-Executive Director

This antibiotic is not licensed for use in dogs. It might not be safe or effective and the correct dose to use is not known. I would not advise doing this.