Estimated dispatch within 1 working day.
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Drontal Plus XL Flavour Tablets are pale brown to brown oval-shaped divisible tablets scored on both sides containing 175 mg praziquantel, 504 mg pyrantel embonate and 525 mg febantel as active constituents and 408.0 mg Artificial beef flavour irradiated.
For the control of the following gastrointestinal roundworms and tapeworms of dogs and puppies.
Toxocara canis, Toxascaris leonina (adult and late immature forms).
Uncinaria stenocephala, Ancylostoma caninum (adults).
Trichuris vulpis (adults).
Echinococcus species, Taenia species, Dipylidium caninum (adults and immature forms).
For oral administration only.
The recommended dose rate is: 15 mg/kg body weight febantel, 14.4 mg/kg pyrantel and 5 mg/kg praziquantel.
This is equivalent to 1 Drontal Plus XL Flavour Tablet per 35 kg bodyweight as follows:
Drontal Plus XL Flavour Tablets
17.5 kg body weight = ½ tablet
>17.5 - 35 kg body weight = 1 tablet
>35 - 52.5 kg body weight = 1½ tablets
>52.5 - 70 kg body weight = 2 tablets
Drontal Dog Tasty Bone Tablets should be used to achieve accurate dosing in dogs weighing less than 17.5 kg. The dose of Drontal Dog Tasty Bone Tablets is equivalent to 1 tablet per 10 kg.
Oral administration: the tablet(s) can be given directly to the dog or disguised in food. No starvation is needed before or after treatement.
For routine treatment a single dose is recommended.
For the control of Toxocara, nursing bitches should be dosed 2 weeks after giving birth and every two weeks until weaning.
For routine control adult dogs should be treated every 3 months. In the event of heavy roundworm infection a repeat dose should be given after 14 days.
Consult a veterinary surgeon before treating pregnant animals for roundworms.
The product may be used during lactation.
Do not exceed the recommended dose when treating pregnant bitches.
Do not use simultaneously with piperazine compounds.
Concurrent use with other cholinergic compounds is not recommended.
In very rare cases slight and transient digestive tract disorders such as vomiting and/or diarrhoea may occur. In individual cases these signs can be accompanied by nonspecific signs such as lethargy, anorexia or hyperactivity.
Drontal Plus XL Flavour Tablets are well tolerated in dogs. In safety studies doses of 5 x or greater gave rise to occasional vomiting.
Fleas serve as intermediate hosts for one common type of tapeworm - Dipylidium caninum. Tapeworm infestation is certain to re-occur unless control of intermediate hosts such as fleas, mice etc. is undertaken.
Since it contains praziquantel, the product is effective against Echinococcus multilocularis, which does not occur in the UK or Ireland but is becoming more common in some European countries. As a precautionary measure to prevent establishment of E. multilocularis in the UK and Ireland, it is recommended that all dogs entering the country be treated with praziquantel.
In case of accidental ingestion, seek medical advice and show package leaflet to the physician.
In the interests of good hygiene, persons administering the tablets directly to the dog, or by adding them to the dog's food, should wash their hands afterwards.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Do not store above 25°C.
Any part-used tablets should be discarded.
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.
Carton containing a PCTFE/PVC- aluminium foil strip of 2, 8 or 48 tablets.
Pharmacotherapeutic group: Anthelmintics, tetrahydropyrimidine. ATC VetCode: QP52AF30.
The product contains three active substances active against roundworms and tapeworms: 1. Febantel, a probenzimidazole, 2. Pyrantel embonate (pamoate) a tetrahydropyrimidine derivative, 3. Praziquantel, a partially hydrogenated pyrazinoisoquinoline derivative.
In this fixed combination product pyrantel and febantel act synergistically against relevant nematodes (ascarids, hookworms and whipworms) in dogs. In particular, the activity spectrum covers Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum and Trichuris vulpis.
The spectrum of activity of praziquantel covers all important cestode species in dogs, in particular all Taenia spp, Dipylidium caninum, Echinococcus granulosus and Echinococcus multilocularis. Praziquantel acts against adult and immature forms of these parasites.
Praziquantel is very rapidly absorbed and distributed throughout the parasite. Both in vivo and in vitro studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolisation of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, especially calcium.
Pyrantel acts as a cholinergic agonist. Its mode of action is to stimulate nicotinic cholinergic receptors of the parasite, induce spastic paralysis and thereby allow removal from the gastrointestinal (GI) system by peristalsis.
Within the mammalian system febantel undergoes ring closure forming fenbendazole and oxfendazole. It is these chemical entities which exert the anthelmintic effect by inhibition of tubulin polymerisation. Formation of microtubules is thereby prevented, resulting in disruption to structures vital to the normal functioning of the helminth. Glucose uptake, in particular, is affected, leading to a depletion in cell ATP. The parasite dies upon exhaustion of its energy reserves, which occurs 2-3 days later.
Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.
For UK delivery, we charge the following:
Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.
For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.
We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.
Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.
Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.
Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.
To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.
*For full details on returns, see our terms and conditions page.
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