UK Registered Veterinary Retailer

Corvental-D Capsules for Dogs

Corvental-D Capsules for Dogs

  • 100mg » Priced per Capsule £1.30
  • 200mg » Priced per Capsule £1.69
  • 500mg » Priced per Capsule £3.10

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Corvental-D capsules are given to dogs to treat congestive heart failure and bronchitis. Most commonly they are prescribed by vets for chronic wheezing and coughing associated with lower airway disease, which is more common in small terrier breeds of dog. A significant improvement in respiratory function can be seen.
Treatment is normally given once daily with food. Dogs to be treated should be weighed so that an accurate dose of Corvental-D can be calculated and given.

Corvental-D is a slight stimulant to the nervous system and can be associated with restlessness and excitement if overdosed. It is sometimes advised not to give Corvental-D immediately before a general anaesthetic. If vomiting occurs, the dose should be reduced in future, or treatment should be stopped.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

200mg » Priced per Capsule

Corvental D Capsules

Qualitative and quantitative composition

Composition (per capsule)

Active ingredient:

Theophylline 100 mg




Indigotine (E132), as colorant 0.048 mg

Titanium dioxide (E171), as colorant 1.152 mg

Ferric oxide (E172) 0.25 mg

For a full list of excipients, see Pharmaceutical particulars section.

Pharmaceutical form

100mg Capsule, hard. Opaque blue/opaque white coloured capsules, size 3. Each capsule half is printed in black with “Th100”.

200mg Capsule, hard. Opaque green/transparent green coloured capsules, size 2. Each capsule half is printed in white with “Th200”.

500mg Capsule, hard. Opaque green/transparent green coloured capsules, size 0/elongated. Each capsule half is printed in white with “Th500

Clinical particulars

Target species


Indications for use, specifying the target species

For the treatment of bronchitis and congestive heart failure in dogs.


Concurrent use of beta-sympathomimetics is contra-indicated, as additive or synergistic interactions, resulting in exaggerated side effects may result.

Do not use in dogs with a known history of epileptiform seizures as convulsions have been reported in patients on theophylline treatment, often with no preceding signs of toxicity and in otherwise apparently normal animals.

Special warnings for each target species

None known.

Special precautions for use

Special precautions for use in animals

Theophylline should be used with caution in patients with liver disease. If vomiting occurs, the dose should be reduced or the treatment discontinued.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

In the case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions (frequency and seriousness)

The following side effects have been reported: restlessness, agitation, excitement, vomiting, diarrhoea, polydipsia, sedation, reduced appetite and polyuria.

If signs of CNS excitement occur, (twitching, restlessness or convulsions) discontinue treatment immediately.

Use during pregnancy, lactation or lay

When theophylline is prescribed to pregnant bitches, the risk-benefit of the treatment should be assessed. Only small amounts of theophylline are excreted in milk.

Interaction with other medicinal products and other forms of interaction

Plasma theophylline levels may increase in patients under treatment with macrolide and fluoroquinolone antibiotics, such as erythromycin and enrofloxacin, and decrease in patients receiving phenobarbitone or phenytoin.

Theophylline may reduce the convulsive threshold in patients receiving ketamine.

Administration of theophylline shortly before halothane anaesthesia may result in arrhythmogenic effects.

Amounts to be administered and administration route

20 mg per kg bodyweight to be given orally once daily only.

Care should be taken to ensure that dogs are weighed carefully and accurately, and the dose does not exceed 20 mg/kg body weight.

Overdose (symptoms, emergency procedures, antidotes), if necessary

There is no specific treatment for theophylline overdose in the dog. The condition should be treated symptomatically with emetics, oral activated charcoal or anti-convulsive drugs as necessary.

Withdrawal period(s)

Not applicable.

Pharmacological particulars

Pharmacotherapeutic group: Systemic drugs for obstructive airway diseases, xanthines.

ATCvet code: QR03DA04

Pharmacodynamic properties

Theophylline is a dimethylated xanthine which was introduced into medicine in 1900. It is similar in structure to the common dietary xanthines, caffeine and theobromine, and has many pharmacological actions. It relaxes smooth muscle, relieves bronchospasm and has a stimulant effect on respiration. Theophylline dilates coronary arteries and increases the strength of contraction of the myocardium. It also acts on the kidney to induce diuresis and is a potent stimulant of the central nervous system.

Pharmacokinetic particulars

Absorption: The methylxanthines are readily absorbed following oral administration. Studies in man have shown that the administration of theophylline with food may slow but not reduce absorption of the drug, and help avoid local irritation of the gastro-intestinal tract. In the absence of food, theophylline solutions or uncoated tablets produce maximal plasma concentration within two hours. The rate and extent of absorption of theophylline differs between various slow release formulations and absorption of the drug appears to be slower at night. However, slow release formulations, if completed absorbed, allow longer dosing intervals with less fluctuation in serum concentration.

Distribution: Theophylline is distributed into all body compartments and human studies have shown that it crosses the placenta and diffuses into breast milk. The drug also crosses the blood brain barrier and enters the central nervous system. The apparent volume of distribution of theophylline in man ranges from 300 to 700 ml/kg and in dogs, 500 to 800 ml/kg. In humans, it is about 50% bound to plasma proteins, but in dogs is lower at about 9%.

Metabolism and Excretion: Little information is available concerning the metabolism and excretion of theophylline in dogs. In man, theophylline is eliminated from the body by hepatic biotransformation into relatively inactive metabolites which are excreted in the urine. Theophylline is metabolised by demethylation and oxidation, mainly to 1,3-dimethyluric acid. D-methyluric acid and 3-methylxanthine are also formed in smaller amounts, and about 10% of the drug is excreted unchanged in the urine. The half life of theophylline in adults is 8 to 9 hours, and in children it is 3.5 hours.

Pharmaceutical particulars

List of excipients

Povidone K-25

Silica Colloidal Anhydrous

Triethyl citrate

Poly (Ethylacrylate, Methylmethacrylate, trimethylammonio Ethylmethacrylate Chloride) 1:2:0.1 150,000 (Eudragit RS 100)

Poly (Ethylacrylate, Methylmethacrylate, trimethylammonio Ethylmethacrylate Chloride) 1:2:0.2 150,000 (Eudragit RL 100)

Talc purified

Capsule cap

Titanium dioxide (E171)

Indigotine (E132)


Water, purified

Capsule body

Titanium dioxide (E171)


Water, purified

Printing Ink

Ferric oxide (E172)


Soya lecithin (E322)


None known.

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 5 years.

Special precautions for storage

Do not store above 30°C. Store in a dry place.

Nature and composition of immediate packaging

Cartons containing 3 or 5 PVC blister strips with aluminium foil seal.

Each blister strip contains 20 capsules.

Not all pack sizes may be marketed.

Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements

Marketing Authorisation Holder (if different from distributor)


Marketing Authorisation Number

Vm 00879/4014

Vm 00879/4015

Vm 00879/4016

Date of the first authorisation or date of renewal

16 February 1993.

Date of revision of the text

January 2016

Any other information

Legal category

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (7)

Q & A

Below are some recent questions we've received regarding Corvental-D Capsules for Dogs, including answers from our team.

8 August 2016 at 5:00pm

Corvental OD

Sue Ferguson

  • VioVet customer since 2016
  • From: Merseyside, United Kingdom

My 41.6kg male labrador has accidentally had 2 500mg capsules today 12 hrs apart. Breakfast and supper. (Stupid humans). Will get be ok? Called vet. No reply vet. Receptionist said they would call back ...

  • Brand Manager

Hi Sue,

Please accept my apologies for the delay in our response, I really hope that you have heard back from your vet in the meantime and your dog did not experience any side effects.

Normally, the maximum recommended dose per kg of bodyweight is 20mg. With each 500mg tablet, your dog receives approximately 12mg/kg, so if he had been given 2 x 500mg in one go he would have received 24mg/ that day, which is slightly over the recommended maximum. The fact that he received the 2 capsules 12 hours apart would have reduced the chances of exceeding this maximum dose, because his body would have already started to eliminate the drug (usually, about half of the amount is eliminated within 8-9 hours).

If this happens again I would again contact your vet for advice and watch out for the following signs and take him to the vet if you are concerned: restlessness, agitation, excitement, twitching, vomiting, diarrhoea, excessive thirst, sedation, reduced appetite and excessive volume and frequency of urination.

I hope this has been helpful.

Kind regards,


29 January 2014 at 8:47pm

Side effects

Carol Cunningham

My dog almost died after being prescribed corvental -D 200mg capsules for a cough. He developed a dangerously high temperature, stopped eating and appeared to be depressed and losing the will to live. After a week on the medication, luckily my husband and I rushed him back to the vet where he was given a series of antibiotics. We do believe if we had not taken our dog back to the vets when we did he would not be here today. Like us humans dogs are individuals and may react differently to prescribed drugs. Why sell such a medication which could possibly do much more harm than good and possibly be fatal, to our four legged friends who cannot complain of the side effects, and whom have to rely on, in my dogs case, his vigilant owner before it was too late for him?

  • Non-Executive Director

I am sorry to hear about your dog. I think you should talk to your vet about the possibility of the Corvental causing the problems. If this might be the case, then there is an official reporting mechanism for suspected adverse reactions to veterinary drugs. These should be reported to the Veterinary Medicine Directorate so that they can be looked into. If a drug is thought to be causing trouble, it will be withdrawn from the market. Please go to to report this very easily on the official website. If you have any trouble with this, email [email protected] and we will help you. However, the truth is that Corvental is unlikely to cause a high temperature or the other symptoms you describe. A chest infection on the other hand could easily do so. The fact that you mention your vet giving antibiotics suggests that your vet thought an infection was involved. If this is the case then it is possible that the Corvental was of no benefit, but it is unlikely to have been the cause of your dog's illness. I wonder what the initial diagnosis was when your dog went onto Corvental and if this diagnosis could be questioned. Again these are matters for your vet.

On a more general note, any individual could potentially react to Corvental, especially if accidentally overdosed. This is true of all drugs. Some drugs are more likely to cause harm than others, but no drugs should ever be given if the risk outweighs the possible benefit. In your case it seems that the antibiotics helped your dog, but on another day a different dog could react badly to that same antibiotic. How then would dogs like yours be treated? We need drugs, but should use them carefully and appropriately. A correct diagnosis is also vitally important, or the drugs do not have a chance to work. Then an appropriate treatment plan has to be started. That is where the skill of your vet comes in, but withdrawing drugs too readily might cause a lot more harm than good. Please do report the matter to the VMD if you feel that would be helpful, but talk to your vet first.