Bimeda Cosecure Bolus

Benefits

• Reduces time & cost of re-servicing
• Reduces cost of cows not in calf
• Reduce cost of fertility treatments
• Healthy embryos – reduced early abortions
• Copper is an integral part of several enzymes with oxidase function e.g. caeruloplasmin, monoamine oxidase, cytochrome oxidase, tyrosinase, lysyl oxidase, cytochrome C and superoxide dismutase; thus copper is essential for a variety of body functions, including growth. Extra copper supplementation is essential in cases of infertility due to the formation of thiomolybdates in the rumen, which search for copper and move into the blood stream if there is not sufficient in the rumen. In the blood stream, thiomolybdates render the enzymes useless by complexing with the copper in them
• Cobalt is an integral part in Vitamin B12 (cyanocobalamin), which is important for several metabolic functions. This vitamin is synthesised by micro-organisms in the rumen and is absorbed from there. Vitamin B12 acts as a co-enzyme in several metabolic pathways and in ruminants its main role is in the metabolism of propionate, which is required for synthesis of glucose via succinate in the liver.
• Selenium is an integral part in the glutathione peroxidase (GSHPx) enzymes, which are involved in the protection from oxidant stress. These enzymes have a synergistic role with Vitamin E and other antioxidants in removing toxic peroxides from tissue and preventing oxidative damage to membranes. Selenium is required in the thyroid gland for the conversion of T4 to T3, the active thyroxine molecule, as selenium is required in the iodothyronine deiodinase enzymes.

Contents

Copper: 13.4g, Cobalt: 0.5g, Selenium: 0.3g as sodium selenate.

Dosage

Ruminating cattle over two months of age and weighing over 100 kg body weight: 2 boluses.

Administer orally using a balling-gun which delivers the bolus directly into the top of the gullet. Great care should be taken not to cause any injury by rough handling or by placing the gun too far inside the throat of the animal. Ensure that each animal has swallowed two boluses by holding the mouth closed and observing the animal for a short time.

Gentle massage of the throat may facilitate swallowing of the boluses. To minimise the risk of regurgitation, avoid rough handling of animals. Do not administer the recommended dosage to animals more frequently than once every 4.5 months to animals receiving concentrates or every 6 months to cattle at pasture.

The boluses can be given at any time, e.g. to dairy cows at drying off or at calving or 30 days post-calving or at artificial insemination.

Boluses are sensitive to sudden temperature changes such as may occur when very cold boluses are swallowed by an animal. It is important that the bolus is at 15 – 20°C (room temperature) prior to administration. In the event of suspected overdose, see carton.