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Adrenacaine Solution for Injection for Cattle

Adrenacaine Solution for Injection for Cattle
100ml Bottle

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  • 100ml Bottle £6.49

Description

Adrenacaine Solution for Injection for Cattle is a clear colourless solution, formulated for use in minor surgical procedures particularly dehorning and disbudding in cattle.

Dosage & Administration


The product should be administered by subcutaneous injection as follows:

Cattle: 2-5 ml

Avoid excessive broaching.

Do not exceed the recommended dose.

Withdrawal Period


Meat: Zero days
Milk: Zero hours

Contra-indictions, Warnings etc


Do not administer by intravenous, intra-articular or epidural injection.

Do not use in cases of hypersensitivity to the active substances or to any of the excipients.

Disposal


Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Further Information


Shelf-life of the veterinary medicinal product as packaged for sale: 2 years
Shelf-life after first opening the immediate packaging: 28 days

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Medication Datasheets

100ml Bottle

Adrenacaine Solution for Injection for Cattle

Qualitative and quantitative composition

Active substance(s):

Procaine Hydrochloride

50mg/ml

Adrenaline (Epinephrine) (as Adrenaline Tartrate)

0.02mg/ml

Excipients:

Chlorocresol (as preservative)

1.0mg/ml

Sodium Metabisulphite E223 (as antioxidant)

1.0mg/ml

For a full list of excipients, see section Pharmaceutical Particulars

Pharmaceutical form

Solution for injection.

A clear colourless solution.

Clinical particulars

Target species

Cattle.

Indications for use, specifying the target species

The product is indicated for use in minor surgical procedures particularly dehorning and disbudding in cattle.

Contraindications

Do not administer by intravenous, intra-articular or epidural injection.

Do not use in cases of hypersensitivity to the active substances or to any of the excipients.

Special Warnings for each target species

None known.

Special precautions for use

Special precautions for use in animals

Care should be taken not to inject the product intravascularly.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Care should be taken to avoid accidental self-injection.

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or label to the physician. Immediately wash off any splashes to the eyes or skin with copious amounts of water.

Seek medical attention if irritation occurs.

Wash hands after use.

Adverse reactions (frequency and seriousness)

None known.

Use during pregnancy, lactation or lay

The product can be administered at any stage of pregnancy or lactation.

Interaction with other medicinal products and other forms of interaction

Procaine may inhibit the action of sulfonamides and their concurrent administration should be avoided.

Amounts to be administered and administration route

The product should be administered by subcutaneous injection as follows:

Cattle: 2-5 ml

Avoid excessive broaching.

Do not exceed the recommended dose.

Overdose (symptoms, emergency procedures, antidotes), if necessary

The product is well tolerated at doses up to 3 times the recommended dose for cattle.

Local anaesthetics used in excess can cause systemic toxicity characterised by CNS effects. If systemic toxicity occurs, as a result of inadvertent intra-vascular injection, the administration of oxygen to treat cardio-respiratory depression and diazepam to control convulsions should be considered.

Withdrawal period

Meat and offal: Zero days

Milk: Zero hours

Pharmacological particulars

Pharmacotherapeutic group: Anaesthetic

ATC Vet Code: QN01BA52

Pharmacodynamic properties

Procaine (p-aminobenzoyl-diethyl aminoethanol) is an amino ester. Procaine, a local anaesthetic shares with other chemical families the ability to act as a membrane stabiliser, by interfering with the ability of excitable cells to generate or transmit impulses. Procaine blocks conduction by decreasing or preventing the large transient increase in the permeability of excitable membranes to Na+ that is produced by a slight depolarisation. The action of local anaesthetics is due to their direct interaction with voltage sensitive Na+ channels.

Adrenaline is composed of two major constituents, the aromatic portion of the molecule consists of 1,2-dihydroxybenzene (catechol), the aliphatic portion consists of ethanol-amine.

The duration of the action of local anaesthetics is proportional to the time which they are in actual contact with nervous tissue. Consequently procedures which localise the drug at the nerve greatly prolong the period of anaesthesia. It has been demonstrated that the addition of epinephrine to local anaesthetic solutions greatly prolongs and intensifies their action. Epinephrine performs a dual service. By decreasing the rate of absorption it not only localises the anaesthetic agent at the desired site but also allows the rate at which the anaesthetic is destroyed in the body to keep pace with the rate at which it enters the circulation. This greatly reduces systemic toxicity.

Pharmacokinetic particulars

Procaine Hydrochloride is a local anaesthetic. The in-vitro half-life of in plasma is less than 1 minute. It is only slightly bound to plasma protein (5.8%) and has a duration of anaesthetic effect of about 50 minutes in man. Adrenaline is added to local anaesthetics such as Procaine Hydrochloride to slow diffusion and limit absorption as it constricts arterioles and capillaries, so prolonging the duration of the effect and lessening the danger of toxicity.

Pharmaceutical particulars

List of excipients

Sodium Metabisulphite (E223)

Chlorocresol

Sodium Chloride

Sodium Hydroxide (pH adjustment)

Hydrochloric Acid (pH adjustment)

Water for Injections

Incompatibilities

In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.

Shelf life

Shelf-life of the veterinary medicinal product as packaged for sale: 2 years

Shelf-life after first opening the immediate packaging: 28 days

Special precautions for storage

Do not store above 25°C.

Protect from light.

Nature and composition of immediate packaging

The product will be supplied in 100 ml amber type I glass vials with bromobutyl bungs and aluminium caps.

Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Marketing Authorisation Holder (if different from distributor)

Norbrook Laboratories Limited

Station Works

Camlough Road

Newry

Co. Down

BT35 6JP

Northern Ireland

Marketing Authorisation Number

Vm 02000/4243 (UK)

Date of the first authorisation or date of renewal

07 July 2004

Date of revision of the text

January 2015

Any other information

Nil.

Legal category

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. To find the exact cost of shipping your item, and to see all options available, follow these steps:

  1. Put the items you wish to order in your basket
  2. Proceed to checkout and enter your delivery address, including country
  3. Delivery information including price will automatically update to what is available to you

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as non-ambient items and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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