UK Registered Veterinary Retailer

Adaptil Spray & Refills for Dogs

Adaptil Spray & Refills for Dogs
Adaptil Spray (60ml)
Original 48ml Refill Vial
Starter Pack: Original Diffuser + 48ml Vial

Images are for illustration purposes only. Packaging may change from time to time and images on our website may or may not be updated.

  • Adaptil Spray (60ml) £18.99
  • Original 48ml Refill Vial £13.14
  • Starter Pack: Original Diffuser + 48ml Vial £18.45

Selection of 3 products from

£13.14 to £18.99


ADAPTIL® can help your dog to adjust better to modern living, by creating a supportive environment to help ease behaviour problems, caused by every day stressful events. This can transform your lives by bringing you closer together. ADAPTIL® is a synthetic copy of the dog appeasing pheromone naturally released by a mother dog to comfort and reassure her new puppies. This pheromone has been shown to have the same comforting effect on puppies and adult dogs in stressful situations, when released through ADAPTIL® products.

Adaptil is non-sedative, non-systemic and as such can be used alongside other types of medications.

The ADAPTIL® products have been improved to ensure that dogs and owners around the world are provided with the best support.

Please note: The diffuser is supplied with just a standard UK 3-pin plug. The diffuser should be replaced every 6 months.

Adaptil is also available in Collars and Express Tablets.

Not sure which Adaptil product to use?

Adaptil Diffuser Adaptil Spray Adaptil Collar
Settle a puppy in a new home Yes Yes
Re-homing a rescue dog Yes Yes
Puppy training Yes
Socialisation Yes
Walks & park visits Yes
Visitors to home Yes
Separation related problems Yes
Noise fears (dog inside) Yes Yes
Noise fears (dog outside) Yes
Multiple fears (inside & outside) Yes Yes
Fear of traveling Yes
Recovery period after hospitalisation Yes Yes

Everyday events can mean everyday unhappiness

Simple things can upset your puppy or dog - new people, car rides, being left alone, fireworks or even a baby being brought into the home. The visible behaviours that you notice can be a result of your dog trying to cope:

  • Drooling and licking of lips

  • Excessive barking and whimpering

  • Soiling in the home

  • Panting & pacing

  • Trying to escape

  • Seeking out owner

  • Destroying household items

To help puppies grow into well-socialised dogs, it is essential to help them feel confident and secure whilst they are learning about the world around them.

Furthermore, in dogs of any age, stress-related issues which remain untreated, may cause health problems.

ADAPTIL® has been scientifically proven to have the same reassuring effect on puppies and adult dogs. It is particularly useful for new or challenging situations.

Over 28 published clinical papers support the use of ADAPTIL®.

It has been used by vets and pet owners worldwide for 14 years.

ADAPTIL® is safe, easy to use and convenient.


The diffuser releases the comforting pheromone in the local environment and should be plugged into the room where the dog spends most of it’s time, perfect for helping your dog feel confident and supported in their environment.

The diffuser will cover an area of 50-70 sq m (one floor of a three bed property) and last for 4 weeks.

Adaptil refills can be purchased to replenish the diffuser every 4 weeks. The diffuser plug should be changed every 6 months.

The Adaptil diffuser is ideal for:

- Nervous dogs

- Dogs that find situations hard to cope with

- Changes to their environment (new arrival, redecorating, moving home)

- Fireworks/loud noises

- Staying home alone

How to use Adaptil Diffuser?

Just screw the vial onto the diffuser unit and plug it into an electric socket.

Then leave the diffuser switched on continuously to keep your dog relaxed and friendly.

The diffuser should be plugged into the room where the dog spends most of its time.

Each diffuser refill covers an area of 50-70m2.

Avoid plugging in the diffuser under shelves or behind doors, curtains or furniture.


The spray is great for dogs that travel, stay in kennels or are visiting the vet. It can be sprayed onto bedding and carriers.

Whether you have just brought a new puppy home or have a much loved adult dog, you may find that from time to time they need help coping with new or challenging situations and the stresses of modern life.

Adaptil Spray can be sprayed directly on:

  • your dog’s bedding
  • inside crates
  • indoor kennels
  • in the car.

How to use Adaptil Spray?

  • Shake the bottle
  • Spray 8 to 10 pumps of Adaptil 15 minutes prior to expected effects and before the dog is introduced into the sprayed environment (car, carrier, kennel etc…).
  • Effects should last approximately 4-5 hours, although each animal will respond differently.
  • Reapply after this time or if you notice a reduced effect.
  • ADAPTIL® Spray can be applied directly on bedding, inside crates, indoor kennels , or in the car, but be sure to apply without the dog in the area to be sprayed (particularly inside the carrier or crate) and allow enough time (15 min) for alcohol evaporation.
  • Adaptil Spray should not be directly sprayed on animals or near an animal’s face.

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. To find the exact cost of shipping your item, and to see all options available, follow these steps:

  1. Put the items you wish to order in your basket
  2. Proceed to checkout and enter your delivery address, including country
  3. Delivery information including price will automatically update to what is available to you

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as non-ambient items and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (280)

Q & A

Below are some recent questions we've received regarding Adaptil Spray & Refills for Dogs, including answers from our team.

25 September 2017 at 2:35pm

Can u use more than one at a time

Paula Gray

  • VioVet customer since 2017
  • From: Hampshire, United Kingdom

Hi we recently homed a dog from blue cross who put adaptil collars on their dogs before leave is it ok to put the disfusser plug in the house as well or it to much for the dog?

  • Website Content Developer

Hi Paula,

Thank you for your question. It is perfectly fine to use the diffuser plug-in together with the collars.

I hope this helps.

17 April 2017 at 2:19pm

How to use spray

Brian millar

Hi do you spray directly onto dog or onto collar and how much do you use

  • Brand Manager

Hi Brian,

Adaptil Spray should only be applied to an environment a dog will be in eg a crate, car, kennel etc, and cannot be sprayed directly onto the dog. If you'd like your dog to have support from Adaptil at all times (inside and outside the house), I'd recommend trying the Adaptil Collars.

Adaptil Spray is great for short-term support like vet trips and car journeys. The effects last 4-5 hours and the spray must be applied to the area (8-10 pumps) about 15 minutes before the dog is introduced. Waiting 15 minutes lets the alcohol the pheromone is delivered in evaporate. The full usage instructions can be found in the description tab here on our website. There is also a section called 'Not sure which Adaptil product to use?' which will show you which of the products are recommended for your situation eg a new puppy/nervous when travelling/ fear of loud noises/ separation anxiety etc.

I hope this helps!

10 February 2017 at 2:20pm

Does size matter?


  • VioVet customer since 2016
  • From: Bedfordshire, United Kingdom

Hi, I have the plug in which currently has the 48ml bottle in it. Would the larger bottle fit in the same plug in unit or they come in different sizes too?

Thanks in advance!

  • Website Content Developer

Hi Kelley,

The only size refill vial is the 48ml one. The Adaptil Spray is 60ml but that is just a spray and doesn't go in the diffuser unit.

I hope this helps.

11 January 2017 at 10:01pm

Heart murmur affected?

Heart murmur

One of my dogs (not the one with the issues) has a heart murmur. Is this product suitable to be used around her?

  • Website Content Developer

Hi there,

There should be no problems whatsoever as Adaptil is a natural product containing a synthetic copy of the dog appeasing pheromone. It is non-sedative, non-systemic and can be used alongside other types of medication. If you need any further advice, we would advise contacting the manufacturer, Ceva, about it.

I hope this helps.

22 September 2016 at 10:11pm

Dap 48ml lasts how long?

Marina Hunter-Gray

  • VioVet customer since 2013
  • From: West Yorkshire, United Kingdom

See above please?

  • Brand Manager

The 48ml refills last 4 weeks on average but it can vary slightly depending on air flow in the room, temperature etc. The diffuser itself should be replaced every 6 months.

14 August 2015 at 4:29pm

Would this affect my budgie

affect other animal's

Would this product affect my budgie or is it safe with birds

  • Non-Executive Director

This is completely fine to use with birds. It is true that birds are often particularly sensitive to inhaled toxic substances, but the Adaptil products are perfectly harmless to all species.

11 August 2015 at 10:40pm

Pregnant wife


My wife is pregnant and the dog appears to have seperation anxiety. Please can you recommend a product whuch is safe to be around my wife. Thanks

  • Non-Executive Director

Adaptil is perfectly safe for your wife, and could certainly help with the anxiety. You could try giving the dog Zylkene too if needed. It should be perfectly safe for your wife to handle that too. Separation anxiety can be helped a great deal by the way the dog is managed around the times it is left so you should seek some expert advice about this. Probably there is good information online, or perhaps even contact to get some help.

27 April 2015 at 10:48am

Dosage of Tablets for a GSD dog

sally mackenzie

Going to Ireland, might be a rough crossing!! she is normally OK on ferry to France although appeared a little 'stressed' once so we went Euro tunnel next. She does travel well but is now 9 years old. Only medication she has every other day is Metacam. Travelling 9th.May .15. thanks.

  • Non-Executive Director

I would give 3 tablets to her 2 hours before you travel. The dose can be repeated 6 hours later.

31 December 2014 at 3:51pm

Adaptil tablets


How long do the tablets last?

  • Non-Executive Director

These tablets are a new addition to the range and we have not yet had any feedback into how effective they are.

The effect would be expected to last for a few hours. If a longer duration of effect is wanted, then they should be combined with one of the pheromone products. A further tablet dose can be given 6 hours or so later if needed.

5 October 2014 at 2:27pm

Maximum area for the diffuser to be effective

Laura Hancock

  • VioVet customer since 2014
  • From: West Midlands, United Kingdom

What is the recommended maximum space the diffuser will work in. We have dogs shut in a fairly large open plan living space and wonder if we may need 2....

  • PHP Developer

One diffuser is suitable to cover an open plan room of 50 to 70m². In most instances one diffuser would be enough.