The owners of missing black and white cat Jester are concerned about his wellbeing as he needs to take pet medication daily.
Jester went missing over a week ago and his owners Lucie Clement and Damien Brigg from Tooting, London, are appealing for help in finding their pet, reports the Wandsworth Guardian.
He is 15-years-old, has one eye, is missing all his teeth and has been battling cancer for the last year and a half.
Miss Clements has put posters up around Tooting and had one report of a sighting but has heard nothing since.
She told the newspaper: "My life is incomplete without him. Any information would mean the world to us. I would describe Jester as being like an old gentleman.
"He is a free spirit and a much loved best friend."
Her main concern is that Jester is somewhere safe and has access to cat food.
Last week, a family in Clifton were reunited with their seven-year-old cat Ollie after he went missing almost five years ago.
He had been living as a stray and was handed into the Cats Protection League where the cat was checked for a microchip, leading to his owners.