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Ypozane is an osaterone acetate treatment for benign prostatic hyperplasia in dogs.
Ypozane is a novel, non-invasive oral treatment containing osaterone acetate for Benign Prostate Hyperplasia in dogs. It is often difficult to diagnose until the disease has progressed to a markedly increase of size of the prostate gland.
The simple, once daily, seven-day treatment has been shown to reduce prostate volume by 40% in just 14 days and show prolonged benefits for up to six months. It is available in four tablet strengths suitable for dogs weighing 3kg to 60kg and given orally, with or without food, at 0.25 to 0.5 mg/kg once daily for seven days.
It is fast-acting, showing a 40% reduction of prostate volume within two weeks, with the effects sustained for up to six months.
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Below are some recent questions we've received regarding Ypozane Tablets for Dogs, including answers from our team.
Paula
Does this meds make dogs more hungry ?
The datasheet for this medication states that 'A transient increase in appetite occurs very commonly.'
Zoe Goundrill
What dosage would i give my 58kilo mastiff please
This is a prescription only medication so you should seek your vet for dosing advice, they will need to prescribe it to you. According to the datasheet the dose is as follows:
Administer 0.25 – 0.5 mg osaterone acetate per kilogram bodyweight, once a day, for 7 days as follows:
*No data are available for dogs less than 3 kg bodyweight.
Tablets can be given either directly into the mouth or with food. The maximum dose should not be exceeded.
The onset of clinical response to treatment is usually seen within 2 weeks. The clinical response persists for at least 5 months after treatment.
Re-evaluation by the veterinarian should take place 5 months after treatment or earlier if clinical signs recur. A decision to retreat at this or at a later time point should be based on veterinary examination taking into account the risk benefit profile of the product. If clinical response to treatment is considerably shorter than expected, a re-evaluation of the diagnosis is necessary.
This means your 58kg dog will likely need 1 x 15mg tablet daily for 7 days. However you should check this with your vet as they may want to recommend an off label doseage.
Crins
Min collie, behandlades för 3 gången med ypazane., först dec.2018, sedan september 2020, och nu för 14 dagar sedan. De första 2 gångerna så fungerade det bra. Men denna tredje gång, är hunden jätte- slö, han orkar knappt gå, men har god aptit, men bara sover. Hunden är 11 år. Hur lång tid kan det ta innan letargin försvinner?
Databladet för denna produkt anger följande:
En övergående aptitökning ökar mycket vanligt.
Övergående beteendeförändringar som ökad eller minskad aktivitet eller mer sällskapligt beteende är vanliga.
Andra biverkningar, inklusive övergående kräkningar och/eller diarré, polyuri/polydipsi, slöhet eller feminiseringssyndrom inklusive bröstkörtelhyperplasi förekommer ovanligt.
En övergående minskning av plasmakortisol sker hos de flesta behandlade djur.
I kliniska prövningar avbröts inte behandlingen med det veterinärmedicinska läkemedlet och alla hundar återhämtade sig utan någon specifik behandling.
Slöheten du beskriver är en av de listade biverkningarna. Jag rekommenderar att du diskuterar detta med din förskrivande veterinär men enligt databladet ska det rensas när behandlingen avbryts.
Nick
Does the drug have any effect on production or quality of semen while dog is on treatment
The data sheet for this product states that 'No adverse effects on semen quality have been observed.' However the effect of the drug on reproductive success is not specifically mentioned, I recommend contacting your prescribing vet so they can contact the manufacturer and advise on this.
Michael
I just wanted to know should we see a improvement 2 weeks after giving the medication or is it from the first day we give the medication and then the two weeks start
The datasheet of this medication states the following:
The onset of clinical response to treatment is usually seen within 2
weeks. The clinical response persists for at least 5 months after
treatment.
This means you should see an improvement of some kind within 2 weeks. I recommend discussing this with your vet though as they will be aware of the entire condition they are treating.