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Veloxa Wormer for Dogs

  • Standard » 2 Tablets £4.75
  • Standard » 4 Tablets £8.11
  • Standard » 8 Tablets £16.23
  • Standard » 104 Tablets £163.08
  • XL » 2 Tablets £11.68
  • XL » 4 Tablets £21.40
  • XL » 8 Tablets £42.39
  • XL » 48 Tablets £230.39

Selection of 8 products from

£4.75 to £230.39

Description

Veloxa is a broad spectrum wormer which is effective against the four most common internal worms in dogs; tapeworm, roundworm, hookworm and whipworm. Veloxa contains the same active ingredients as the leading wormer on the market, and comes in a tasty beef flavoured chewable tablet which can be fed easily without the need to mix with food.

Produced by the manufacturer of Frontline, experts in anti-parasite products for pets.

Veloxa Dosage

Bodyweight (kg)

Number of chewable tablets

2.5 - 5

½

> 5 - 10

1

> 10 - 15

> 15 - 20

2

> 20- 25

> 25 - 30

3

For dogs weighing more than 30 kg (i.e. >30 kg) the XL strength should be used.

Veloxa XL Dosage

Bodyweight (kg)

Number of chewable tablets

17.5

½

>17.5-35

1

>35-52.5

>52.5-70

2

Qualitative and quantitative composition

Each Veloxa chewable tablet contains:

Active substances

Febantel 150 mg

Pyrantel 50 mg (corresponding to Pyrantel embonate 144 mg)

Praziquantel 50 mg

Each Veloxa XL chewable tablet contains:

Active substances

Febantel 525 mg

Pyrantel 175 mg (corresponding to Pyrantel embonate 504 mg)

Praziquantel 175 mg

For a full list of excipients, see below.

Pharmaceutical form

Chewable tablet.

Brownish, oval, divisible chewable tablet. It can be divided into equal halves.

Clinical particulars

Target species

Dogs

Indications for use

Broad-spectrum anthelmintic for treatment of mixed infections by the following roundworms and tapeworms in dogs and puppies:

Ascarids: Toxocara canis, Toxascaris leonina (adult and late immature forms)

Hookworms: Uncinaria stenocephala, Ancylostoma caninum (adults)

Whipworms: Trichuris vulpis (adults)

Tapeworms: Echinococcus spp., Taenia spp. and Dipylidium caninum (adult and immature forms).

Contra-indications

Do not use in animals with a known hypersensitivity to any of the active substances or the excipients.

Special warnings for each target species

Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.

Fleas serve as intermediate hosts for one common type of tapeworm - Dipylidium caninum. Tapeworm infestation is certain to reoccur unless control of intermediate hosts such as fleas, mice, etc. is undertaken. Tapeworm infestation is unlikely in pups less than 6 weeks of age.

Special precautions for use in animals

Veloxa is recommended for use in dogs less than 17.5 kg bodyweight. Veloxa XL is recommended for use in dogs over 17.5 kg bodyweight.

Special precautions to be taken by the person administering the medicinal product to animals

In the interests of good hygiene, persons administering the chewable tablet directly to a dog or by adding it to the dog's food, should wash their hands afterwards. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions

In very rare cases transient, mild gastrointestinal signs (e.g. vomiting) may occur.

Use during pregnancy, lactation or lay

Teratogenic effects attributed to high doses of febantel have been reported in sheep and rats. No studies have been performed in dogs during early pregnancy. Use of the product during pregnancy should be in accordance with a benefit/risk assessment by the responsible veterinarian. It is recommended that the product is not used in dogs during the first 4 weeks of pregnancy. Do not exceed the stated dose when treating pregnant bitches.

The chewable tablets may be used during lactation.

Interactions

Do not use simultaneously with piperazine as the anthelmintic effects of pyrantel and piperazine may be antagonised.

Concurrent use with other cholinergic compounds can lead to toxicity.

Plasma concentrations of praziquantel may be decreased by concomitant administration with drugs that increase the activity of cytochrome P-450 enzymes (e.g. dexamethasone, phenobarbital).

Amounts to be administered and administration route

For oral administration only.

Veloxa Dosage

For treatment of dogs 1 chewable tablet per 10 kg bodyweight orally (15 mg febantel, 5 mg pyrantel (as embonate) and 5 mg praziquantel/kg bodyweight).

Bodyweight (kg)

Number of chewable tablets

2.5 - 5

½

> 5 - 10

1

> 10 - 15

> 15 - 20

2

> 20- 25

> 25 - 30

3

For dogs weighing more than 30 kg (i.e. >30 kg) the XL strength should be used.

Veloxa XL Dosage

For treatment of dogs 1 chewable tablet per 35 kg bodyweight orally (15 mg febantel, 5 mg pyrantel (as embonate) and 5 mg praziquantel/kg body weight).

Bodyweight (kg)

Number of chewable tablets

17.5

½

>17.5-35

1

>35-52.5

>52.5-70

2

Do not use for treatment of dogs weighing less than 17.5 kg (i.e. <17.5 kg).

Administration

The chewable tablets can be given directly to the dog or disguised in food. No starvation is needed before or after treatment. Due to a lipid-coating of praziquantel and added flavour, the chewable tablets are taken by most dogs voluntarily.

Duration of treatment

A single dose shall be used. If there is a risk of re-infestation, the advice of a veterinarian should be sought regarding the need for and the frequency of repeat administration.

Overdose

The combination of praziquantel, pyrantel embonate and febantel is well tolerated in dogs. In safety studies, a single dose of 5 times the recommended dose or greater gave rise to occasional vomiting.

Pharmacological particulars

Pharmacodynamic properties

In this fixed combination product pyrantel and febantel act against all relevant nematodes (ascarids, hookworms and whipworms) in dogs. In particular, the activity spectrum covers Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum and Trichuris vulpis. This combination shows synergistic activity in the case of hookworms and febantel is effective against T. vulpis. The spectrum of activity of praziquantel covers all important cestode species in dogs, in particular all Taenia spp, Dipylidium caninum, Echinococcus granulosus and Echinococcus multilocularis. Praziquantel acts against adult and immature forms of these parasites.

Praziquantel is very rapidly absorbed and distributed throughout the parasite. Both in vitro and in vivo studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolisation of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, especially calcium.

Pyrantel acts as a cholinergic agonist. Its mode of action is to stimulate nicotinic cholinergic receptors of the parasite, induce spastic paralysis and thereby allow removal from the gastrointestinal system by peristalsis.

Within the mammalian system febantel undergoes ring closure forming fenbendazole and oxfendazole. It is these chemical entities which exert the anthelmintic effect by inhibition of tubulin polymerisation. Formation of microtubules is thereby prevented, resulting in disruption to structures vital to the normal functioning of the helminth. Glucose uptake, in particular, is affected, leading to depletion in cell ATP. The parasite dies upon exhaustion of its energy reserves, which occurs 2-3 days later.

Pharmacokinetic properties

After oral administration, praziquantel is almost completely absorbed from the intestinal tract. After absorption, the drug is widely distributed in the organism, metabolised into inactive forms in the liver and secreted in bile. It is excreted within 24 hours to more than 95% of the administered dosage.

The embonate salt of pyrantel has low aqueous solubility, an attribute that reduces absorption from the gut and allows the drug to reach and be effective against parasites in the large intestine. Following absorption, pyrantel embonate is quickly and almost completely metabolised into inactive components which are rapidly excreted in the urine.

Febantel is an inactive pro-drug which is absorbed and then metabolised relatively rapidly to a number of metabolites, including fenbendazole and oxfendazole, which have anthelmintic activity.

Following the single oral administration of this product the maximum plasma concentrations of praziquantel, pyrantel, fenbendazole and oxfendazole were found 327, 81, 128 and 165 ng/ml and were obtained after 2.2, 4.5, 5.2 and 6.3 hours.

Pharmaceutical particulars

Excipients

Cetyl palmitate, Starch (pregelatinised), Sodium starch glycolate (type A), Colloidal anhydrous silica, Magnesium stearate, Artificial beef flavour.

Major incompatibilities

Not applicable.

Shelf life

Shelf-life of the product as packaged for sale: 2 years.

Chewable tablet halves should be used within 2 days.

Special precautions for storage

This product does not require any special storage conditions.

Each time an unused half chewable tablet is stored it should be returned to the open blister space and inserted back into the folding box and kept in a safe place out of the reach of children.

Immediate packaging

PVC and aluminium blisters containing 2 or 8 (Veloxa strength only) chewable tablets.

Veloxa packs: 2, 4, 8, and 104 chewable tablets.

Veloxa XL packs: 2, 4, 8, 48 and 96 chewable tablets.

Not all pack sizes may be marketed.

Disposal

Any unused products or waste materials derived from such products should be disposed of in accordance with local requirements.

Marketing Authorisation Holder (if different from distributor)

Lavet Pharmaceuticals Ltd

1161 Budapest

Ottó u. 14

Hungary

Marketing authorisation number

Vm 32823/4010.

Legal category

NFA-VPS

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Reviews of Veloxa Wormer for Dogs

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Questions & Answers for Veloxa Wormer for Dogs

Below are some recent questions we've received regarding Veloxa Wormer for Dogs, including answers from our team.

Ask Your Own Question

Is this better?

6th Nov 2015
Nat c

I see this works against more worms than drontal. Is it therefore better to give this product? Cheers

John Cousins
  • Veterinary Surgeon

It can be confusing to compare these things when the common names of different worms are used. In fact this product is virtually identical to Drontal and will have exactly the same level of activity against all the same types of worm. You can use either product and it should make no difference to the worms. The flavouring and bulking agents are different, but that is all.

Re use of veloxa

7th Jun 2015
Julie

How often should veloxa be used is it every 3 months?

John Cousins
  • Veterinary Surgeon

Generally speaking a dose every three months is appropriate for adult dogs using this or any other multi-wormer. Strictly speaking the best dosing frequency depends on the precise circumstances the dog is kept in and the potential for picking up new worms from the environment etc. However giving a dose every 3 months is usually fine.