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The Seresto Collar is made from a special polymer which slowly releases the active ingredients over a period of up to 8 months. The collar is worn continuously and repels fleas, ticks and lice through the action of the safe and well known anti-parasite activity of imidacloprid and flumethrin.
We are not aware of any other product which provides such effective activity for such a long period.
Seresto - Innovative collar matrix enables release of consistent dose
* Kills fleas and repels and kills ticks
* Reduces risk of transmission of vector-borne diseases
* Water resistant and odour free
* Two safety release mechanisms
Seresto Collar 1.25g + 0.56g collar for cats up to 8kg
Dosage and Administration
One collar per animal to be fitted round neck, allow for 2 fingers to fit between the collar and the pets neck to ensure it fits comfortably. Cut off any excess length exceeding beyond 2cm.
The collar should be worn continuously for the 8 month protection period and should be removed after the treatment period. Check regularly and adjust if necessary especially when puppies or kittens are rapidly growing.
Do not use on kittens less than 10 weeks of age, do not use on puppies less than 7 weeks of age.
Innovative technology in flea and tick protection
Seresto's unique polymer matrix enables it to release controlled doses of its active ingredients which are both well tolerated in cats & dogs.
Proven to work against adult fleas, larval flea stages and lice
Proven to repel and kill adult ticks, larve and nymphs
You may initially notice a white powder residue on the surface of the collar. This is stearic acid, a substance graded for food use, which helps release the collar during the moulding process.
How the patented controlled-release mechanism works:
* Innovative polymer matrix stores active ingredients within the collar
* Collar does not release active ingredients until applied to the animal
* Active ingredient molecules migrate to form a microlayer on collar surface
* Active ingredients are transferred from collar to lipid layer of skin and hair
Mode of Action
* Neutral oils help active ingredients diffuse and spread through the lipid layer
Active ingredients continue to migrate from matrix to lipid layer as needed
Optimal acaricidal/insecticidal protection is sustained for up to 8 months at a consistent and effective dose.
Seresto is a result of a multidisciplinary effort based on Bayers unique experience in insecticides research, polymer chemistry and veterinary parasiticides development.
Seresto - manufactured by Bayer
All prices include VAT where applicable.
A grey, odour-free collar containing the following active substances:
Seresto 1.25 g + 0.56 g, collar for cats: 38 cm (12.5 g) containing 1.25 g imidacloprid and 0.56 g flumethrin
Seresto 1.25 g + 0.56 g, collar for dogs ≤ 8 kg: 38 cm (12.5 g) containing 1.25 g imidacloprid and 0.56 g flumethrin
Seresto 4.50 g + 2.03 g, collar for dogs >8 kg: 70 cm (45 g) containing 4.5 g imidacloprid and 2.03 g flumethrin
The collar also contains the following excipients:
Titanium dioxide (E 171)
Iron oxide black (E 172)
For cats use Seresto 1.25 g + 0.56 g, collar for cats
For dogs ≤ 8 kg use Seresto 1.25 g + 0.56 g, collar for dogs ≤ 8 kg
For dogs > 8 kg use Seresto 4.50 g + 2.03 g, collar for dogs > 8 kg
For the treatment and prevention of flea (Ctenocephalides felis) infestation for 7 to 8 months.
Protects the animal’s immediate surroundings against flea larvae development for 10 weeks.
Seresto can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD).
The product has persistent acaricidal (killing) efficacy (Ixodes ricinus, Rhipicephalus turanicus) and repellent (anti-feeding) efficacy against tick infestations (Ixodes ricinus) for 8 months. It is effective against larvae, nymphs and adult ticks.
Ticks already on the cat prior to treatment may not be killed within 48 hours after collar application and may remain attached and visible. Therefore removal of ticks already on the cat at the time of application is recommended. The prevention of infestations with new ticks starts within two days after application of the collar.
For the treatment and prevention of flea (Ctenocephalides felis, C. canis) infestation for 7 to 8 months. Protects the animal’s immediate surroundings against flea larvae development for 8 months.
Seresto can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD).
The product has persistent acaricidal (killing) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus) and repellent (anti-feeding) efficacy against tick infestations (Ixodes ricinus, Rhipicephalus sanguineus) for 8 months. It is effective against larvae, nymphs and adult ticks.
Ticks already on the dog prior to treatment may not be killed within 48 hours after collar application and may remain attached and visible. Therefore removal of ticks already on the dog at the time of application is recommended. The prevention of infestations with new ticks starts within two days after application of the collar.
The product provides indirect protection against the transmission of the pathogens Babesia canis vogeli and Ehrlichia canis from the tick vector Rhipicephalus sanguineus, thereby reducing the risk of canine babesiosis and canine ehrlichiosis for 7 months.
Reduction of the risk of infection with Leishmania infantum via transmission by sand flies for up to 8 months.
For treatment of biting/chewing lice (Trichodectes canis) infestation.
Cutaneous use. One collar per animal to be fastened around the neck.
Cats receive one collar of 38 cm length.
Small dogs up to, and including, 8 kg body weight receive one Seresto collar for dogs ≤ 8kg of 38 cm length.
Dogs above 8 kg receive one Seresto collar for dogs > 8 kg of 70 cm length.
For external use only.
Remove collar from protective bag directly before use. Unroll collar and make sure that there are no remnants from the plastic connectors inside the collar. Adjust the collar around the animal's neck without tightening it too tight (as a guide, it should be possible to insert 2 fingers between the collar and the neck). Pull excess collar through the loop and cut off any excess length extending beyond 2 cm.
Fitting the collar to the cat (see diagram)
Fitting the collar to the dog (see diagram)
The collar should be worn continuously for the 8 month protection period and should be removed after the treatment period. Check periodically and adjust fit if necessary, especially when puppies and kittens are rapidly growing.
Cats: This collar is designed with a safety-closure mechanism. In the unlikely event of a cat being trapped, the cat's own strength is sufficient to widen the collar to allow for quick release.
Laboratory studies with either flumethrin or imidacloprid in rats and rabbits have not produced any effects on fertility or reproduction and showed no teratogenic or foetotoxic effects. However, the safety of the veterinary medicinal product has not been established in target animals during pregnancy and lactation and in the absence of available data, the product is therefore not recommended in pregnant and lactating bitches or queens.
Do not treat kittens less than 10 weeks of age.
Do not treat puppies less than 7 weeks of age.
Do not use in the case of known hypersensitivity to the active substances or to any of the excipients.
Ticks will be killed and fall off the host within 24 to 48 hours after infestation without having had a blood meal, as a rule. An attachment of single ticks after treatment cannot be excluded. For this reason, a transmission of infectious diseases by ticks cannot be completely excluded if conditions are unfavourable.
Ideally, the collar should be applied before the beginning of the flea or tick season.
Although a significant reduction in the incidence of Leishmania infantum in dogs has been demonstrated, the product has shown variable repellent (anti-feeding) and insecticidal efficacy against the sand fly Phlebotomus perniciosus. As a result, bites by sand flies may occur, and the transmission of Leishmania infantum cannot be completely excluded. The collar should be applied just before the beginning of the period of activity of sand fly vectors corresponding to the Leishmania infantum transmission season and worn continuously throughout the risk period.
As in all longterm topical products, periods of excessive seasonal hair shedding may lead to transient slight reduction of efficacy by loss of hair-bound portions of the active ingredients. Replenishment from the collar starts immediately so that full efficacy will be re-established without any additional treatment or collar replacement.
For optimum control of flea problems in heavily infested households it may be necessary to treat the environment with a suitable insecticide.
The product is water resistant; it remains effective if the animal becomes wet. However, prolonged, intense exposure to water or extensive shampooing should be avoided as the duration of activity may be reduced. Studies show that monthly shampooing or water immersion does not significantly shorten the 8 months efficacy duration for ticks after redistribution of the active substances in the coat whereas the product’s flea efficacy gradually decreased, starting in the 5th month. The influence of shampooing or water immersion regarding the transmission of canine leishmaniosis has not been examined.
In rare cases mild behavioural disorders that may include scratching at the application site may be observed in animals that are not used to wearing collars on the first few days after fitting. Ensure that the collar is not fitted too tightly.
Mild application site reactions such as pruritus, erythema and hair loss may occur. These have been reported as rare in dogs and uncommon in cats and usually resolve within 1 to 2 weeks without the need for collar removal. In single cases, a temporary collar removal may be recommended until the symptoms have disappeared.
In very rare cases in dogs and rare cases in cats, application site reactions such as dermatitis, inflammation, eczema or lesions may occur and in these instances, collar removal is recommended
In rare cases in dogs neurological symptoms such as ataxia, convulsions and tremor may occur. In these cases collar removal is recommended.
Also, in rare case in cats and dogs, slight and transient reactions as depression, change of food intake, salivation, vomiting and diarrhoea might occur initially.
As in other topical applications, allergic contact dermatitis might occur in hypersensitive animals.
The frequency of possible adverse effects is defined using the following convention:very common (affects more than 1 animal in 10)common (affects 1 to 10 animals in 100)uncommon (affects 1 to 10 animals in 1,000)rare (affects 1 to 10 animals in 10,000)very rare (affects less than 1 animals in 10,000)
Due to the nature of the collar, overdosage is unlikely and signs of overdosage are not to be expected.
An overdosage of 5 collars around the neck was investigated in adult cats and dogs for an 8 month period, and in 7 week old puppies and 10 week old kittens for a 6 month period and no other adverse effects were observed than those already described in this section.
In the unlikely event of the animal eating the collar mild gastrointestinal symptoms (e.g. loose stool) may occur.
Keep the bag with the collar in the outer packaging until use.
As with any veterinary medicinal product, do not allow small children to play with the collar, or to put it into their mouths. Pets wearing the collar should not be allowed to sleep in the same bed as their owners, especially children.
People with known hypersensitivity to the ingredients of the collar should avoid contact with the collar.
Immediately dispose of any remnants or cut-offs of the collar (see Dosage and administration section).
Wash hands with cold water after fitting the collar.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
This product should not enter water courses as it may be dangerous for fish and other aquatic organisms.
Shelf-life of the veterinary medicinal product as packaged for sale: 5 years.
This veterinary medicinal product does not require any special storage conditions.
Tin containing one single 38 cm or 70 cm polyvinyl chloride-based collar packed into a PETP/PE bag.
Pharmacotherapeutic group: ectoparasiticides, insecticides and repellents, pyrethrins and pyrethroids, Flumethrin combinations. ATCvet code: QP53AC55
Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified as a chloronicotinyl nitroguanidine. Imidacloprid is active against larval flea stages, adult fleas and lice. In cats, activity against C.felis starts immediately after application of the collar. In dogs, efficacy against fleas (Ctenocephalides felis and Ctenocephalides canis) starts within 48 hours after application of the collar. In addition to the indications listed under the 'Uses' section, an activity against Pulex irritans fleas has been demonstrated.
Imidacloprid has a high affinity for the nicotinergic acetylcholine receptors in the post-synaptic region of the central nervous system (CNS) of the flea. The ensuing inhibition of cholinergic transmission in insects results in paralysis and death. Due to the weak nature of the interaction with mammalian nicotinergic receptors and the postulated poor penetration through the blood-brain barrier in mammals, it has virtually no effect on the mammalian CNS. Imidacloprid has minimal pharmacological activity in mammals.
Flumethrin is an ectoparasiticide of the synthetic pyrethroid group. According to current knowledge the synthetic pyrethroids interfere with the sodium channel of nerve cell membranes, resulting in a delay in repolarisation of the nerve and finally killing of the parasite. In studies on structure-activity relationship of a number of pyrethroids, interference with receptors of a certain chiral conformation was noted thereby causing a selective activity on ectoparasites. No anti-cholinesterase activity was noted with these compounds. Flumethrin is responsible for the product’s acaricidal activity and also prevents production of fertile eggs by its lethal effect on female ticks. In an in-vitro study 5 to 10 % of Rhipicephalus sanguineus ticks exposed to a sublethal dose of 4 mg flumethrin/L laid eggs which had a modified appearance (shrivelled, dull and dry) indicating a sterilising effect.
In addition to the indications listed under ‘Uses’ section, activity has been demonstrated in cats against Ixodes hexagonus and the non-European tick species Amblyomma americanum and in dogs against I. hexagonus, I. scapularis and the non-European tick species Dermacentor variabilis and the Australian paralysis tick I. holocyclus. The product provides repellent (anti-feeding) activity against the claimed ticks, thus preventing repelled parasites from taking a blood meal and thereby indirectly aids in the reduction of the risk of Vector-Borne Disease transmission.
In cats, indirect protection against the transmission of Cytauxzoon felis (transmitted by Amblyomma americanum ticks) has been shown in one laboratory study in a small number of animals at one month after treatment, thereby reducing the risk of diseases caused by this pathogen under the conditions of this study. In dogs, in addition to the pathogens listed under 'Uses' section, indirect protection against the transmission of Babesia canis canis (by Dermacentor reticulatus ticks) has been shown in one laboratory study at day 28 after treatment, and indirect protection against the transmission of Anaplasma phagocytophilum (by Ixodes ricinus ticks) has been shown in one laboratory study at 2 months after treatment, thereby reducing the risk of diseases caused by these pathogens under the conditions of these studies.
Data from efficacy studies against sand flies (Phlebotomus perniciosus) showed a variable sand fly repellent (anti-feeding) efficacy ranging from 65 to 89% for 7-8 months following initial application of the collar. Data from 3 clinical field studies performed in endemic areas indicate a significant reduction in the risk of Leishmania infantum transmission by sand flies in treated dogs compared to non-treated dogs. Depending on the infection pressure by sand flies the efficacy in the reduction of the risk of infection with leishmaniosis ranged from 88.3 to 100%.
The collars were able to improve the Sarcoptes scabiei infestation in pre-infested dogs leading to a full cure after three months.
Cats and Dogs: Both active ingredients are slowly and continuously released in low concentrations from the polymer matrix system of the collar towards the animal. Both actives are present in the cat’s or dog’s haircoat in acaricidal/insecticidal concentrations during the entire efficacy period. The active substances spread from the site of direct contact over the entire skin surface. Target animal overdose and serum kinetic studies have established that imidacloprid reached the systemic circulation transiently while flumethrin was mostly not measurable. Oral absorption of both active substances is not relevant for the clinical efficacy.
Seresto 1.25 g + 0.56 g, collar for cats: Vm 00010/4173
Seresto 1.25 g + 0.56 g, collar for dogs ≤ 8 kg: Vm 00010/4174
Seresto 4.50 g + 2.03 g, collar for dogs >8 kg: Vm 00010/4176
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Below are some recent questions we've received regarding Seresto Flea and Tick Collar, including answers from our team.
My cat has a name barrel and magnet that needs to fit over the collar each on a metal ring. Can you advise the width of the collar please.
It is not actually recommended by Bayer to attach things to the Seresto collar as it can impair the safety release mechanism. It is however fine to use the Seresto collar alongside a normal collar and will not damage it.
Safe with other products?
Is it safe to use in conjunction with spot ones such as Frontline etc?
Yes it is safe to use this collar with Frontline and many of the other spot ons as long as the active ingredients are different. However you should not need to use Frontline with the collar since they are both effective against fleas and ticks.
Please can you let me know what the shelf life of these collars are, I was going to buy a couple to save on prescription charges, do they loose there effectiveness over time or are they sealed and the clock starts ticking once they are opened.
They are sealed and the clock does indeed only start once you open them. The expiry date varies from time to time, but is usually about 18 months. If you need a long date, then you can state this when you place the order. (Give us a date when you intend to use them.)
I was wondering if you could confirm if this collar is safe for older pets and for pets with pre existing health conditions? I have a 12 year old German Shepherd with arthritis and an 11 year old Lurcher in the early stages of heart failure (grade 4 heart murmur) and an unknown allergy condition so want to know if this collar is safe to use on both of them? I don't normally use any chemicals on them but picking 6-8 ticks off a day at the moment!!
This is regarded as a safe product and it should not have any adverse effect on either of your dogs, though you are right to be cautious about this. Any product which kills external parasites (particularly ticks) may have some potential toxic effects on your dog, especially if used at a higher than recommended dose. However having said that, the danger from disease transmitted by tick bites is much greater. It is virtually impossible to find all the ticks before they have had a chance to feed on your dog, so the risk associated with treatment is likely to be very much less than that from not treating effectively. This is a prescription product so you can only buy it with a prescription from your vet, who will have assessed it as safe for your dogs before prescribing it. I would recommend you do use it if your vet prescribes it.
I just wondered if the collar is effective against ticks for dogs around 40-50kg and the actual measurements of the collar for thicker necked dogs please?
The large dog collar has a large weight range if it's anything between 8-50kg?
This product should be effective for a dog in that weight range. The collar is 70cm long when bought.
Miss Lisa E Simms
Are this safe for collies that could be sensitive to ivermectin?
The ingredients of this collar are very different from ivermectin and it is safe for all dog breeds, including collies. (It should not be used on cats however.)
Hello. Greyhounds in general are not to wear flea collars as very sensitive to chemicals in them so I usually use Frontline as treats topically rather than entering my dog's blood system. Is this collar safe for Greyhounds and if so, what is not in it that would normally cause harm to greyhounds. Thank you.
Some people believe that ggreyhounds are more sensitive to flea treatments that most dogs but this is not my experience. They do have a thin, sensitive skin, but tolerate most flea treatments perfectly well. Seresto releases its active ingredients onto the skin where they have a topical effect, they are not absorbed systemically. I believe Seresto should be safe and effective for your greyhound.
How do I go about getting a prescription to be able to buy these please? Would I have to take each pet to the vet? If so, won't they expect to sell me their choice of product?
Most vets generally expect to sell any medication they prescribe. However it is becoming much more widespread for their clients to ask to buy prescribed medication elsewhere as this often makes it much cheaper. Most vets do not suggest this to their customers, but they do accept it in a professional manner if asked. Some vets will happily prescribe products like Seresto without seeing the dog, as long as they have seen the dog in the recent past and could be said to be responsible for the veterinary care of the dog. Some will want to see a dog every time they are asked to prescribe anything. It is also possible that your vet will not agree with you that Seresto is suitable and they might suggest another product, which is in fact up to them. Most vets are very reasonable and will actually try to be helpful, though this varies of course.
I have two dogs which have had the seresto collar on for roughly a month now, but I have recently found two ticks in the house?
It is very unusual to find ticks in the house under any circumstances. If you are sure of the correct identification, then the most likely explanation would be that the ticks climbed onto your dog outside then dropped off again in your house, possibly repelled by the collar. Ticks do not usually complete their life cycle within a house, unlike fleas. Whatever the explanation, it does not mean the collars are not working unless you find the parasites on the dogs. Did the ticks look well fed or in search of food (size of abdomen)?
If i use this as a treatment for ticks/fleas would i still need to use my normal flea treatment obtained from our Vets
thanks in advance
You would not need to use a treatment on your animal (spot-on, tablets etc) at the same time that the collar is on. It is recommended, however, that you treat the environment to get rid of any fleas which may have been on your pet. Usually any place that the pet goes should be treated with something like Virbac Indorex Household Flea Spray.