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Nobivac Pi provides protection against Parainfluenza virus in dogs. It is supplied as a freeze-dried powder to be mixed with solvent before use.
Lyophilisate and solvent for suspension for injection containing Live attenuated canine parainfluenza virus (CPi) strain Cornell: ≥5.5 log10 and ≤ 7.3 log10 TCID50* per dose.
* TCID50 = median Tissue Culture Infective Dose
For active immunisation of dogs from the age of 8 weeks onwards to reduce clinical signs of canine para-influenza infection and to reduce viral shedding.
Onset of immunity: 4 weeks after vaccination.
Duration of immunity: has not been demonstrated, but an anamnestic response is produced in dogs given a revaccination one year after basic vaccination.
One ml solvent must be used to reconstitute the freeze-dried Nobivac Pi vaccine.
One ml of the reconstituted vaccine should be given by subcutaneous injection.
Nobivac Pi has been shown to be safe for use in pregnant bitches that have been vaccinated before pregnancy with the Pi vaccine of the Nobivac series.
•Before the age of 12 weeks:
Two vaccinations, each with a single dose: the first vaccination from the age of 8 weeks onwards and the second vaccination 2-4 weeks later.
•From the age of 12 weeks onwards:
Single vaccination, with one dose per animal.
Every year with a single dose.
A protective antibody titre is not accomplished in all vaccinated dogs.
As maternally derived passive antibodies can interfere with the response to vaccination in very young animals, a final dose at 10 weeks of age or older is recommended.
Special precautions for use in animals
Vaccinate only healthy dogs.
Sterile equipment should be used for administration.
Some dogs may show discomfort during injection.
A diffuse swelling, up to 5 mm in diameter, may be observed at the site of injection. Occasionally this swelling may be hard and painful and last for up to 3 days post injection.
After subcutaneous administration with the lepto and/or rabies vaccines of the Nobivac series (where these products and their combined use are authorised), a diffuse swelling may be observed at the injection site in most puppies. Occasionally this swelling may be hard, painful and more severe but this will diminish gradually and disappear after 2-3 weeks.
Hypersensitivity reactions may occur. In the event of an anaphylactic reaction appropriate treatment such as adrenaline should be administered without delay.
After administration of an overdose, not different from a single dose. In some dogs the swelling may be more painful or may be observed for a longer period.
No information is available on the compatibility of this vaccine with any other except the lepto and/or rabies vaccines of the Nobivac series. These liquid vaccines can be used to reconstitute the freeze-dried Nobivac Pi, where these products and their combined use are authorised. Therefore the safety and efficacy of this product when used with any other vaccine than these (either when used on the same day or at different times) has not been demonstrated.
Do not mix with any other vaccine except the diluent supplied with the product or with the lepto and/or rabies vaccines of the Nobivac series (where these products and their combined use are authorised).
In the case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
For animal treatment only. Keep out of reach and sight of children.
Store in a refrigerator (at 2° to 8°C) in the original package. Do not freeze. Protect from light. Care should be taken to avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use. In-use shelf life: 30 minutes.
Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities.
Cartons of 10 and 50 single dose vials. Not all presentations may be marketed.
Intervet International BV, NL.
Represented by Intervet UK Ltd.
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