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Nobivac Myxo-RHD Vaccine for Rabbits

  • Box of 5 Doses £61.20
  • Single Dose £12.24

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Nobivac Myxo-RHD provides protection against Myxomatosis and also Rabbit Haemorrhagic Disease. A single injection is adequate, but must be repeated every 12 months. Myxomatosis is transmitted between rabbits by biting insects which may travel a long distance, so it is possible for domestic rabbits to pick up the disease from wild rabbits even when there is no apparent contact between them. The virus which causes RHD can be transmitted on clothing, footwear, feeding utensils etc so rabbit handlers must be aware that accidental transmission to non-vaccinated rabbits is possible. Both diseases are regarded as common in wild rabbits in the UK. Nobivac Myxo-RHD is injected under the skin any time from 5 weeks of age, with immunity being regarded as effective after 3 weeks.

Qualitative and quantitative composition

Each dose of reconstituted vaccine contains:

Active substance: Live myxoma vectored RHD virus strain 009: ≥103.0 and ≤106.1 FFU*.

*Focus Forming Units.

Excipients: For a full list of excipients, see section “Pharmaceutical Particulars”.

Pharmaceutical form

Lyophilisate and solvent for suspension for injection.

Clinical particulars

Target species


Indications for use

For active immunisation of rabbits from 5 weeks of age onwards to reduce mortality and clinical signs of myxomatosis and to prevent mortality due to rabbit haemorrhagic disease.

Onset of immunity: 3 weeks.

Duration of immunity: 1 year.



Special warnings for each target species


Special precautions for use

Vaccinate only healthy rabbits.

Rabbits that have been vaccinated previously with another myxomatosis vaccine, or that have experienced natural myxomatosis infection in the field, may not develop a proper immune response against rabbit haemorrhagic disease following vaccination.

User warnings: None.

Adverse reaction

A transient temperature increase of 1-2°C can occur.

A small, non-painful swelling (maximum 2 cm diameter) at the injection site is commonly observed within the first two weeks after vaccination. The swelling will resolve completely by 3 weeks after vaccination.

Use during pregnancy, lactation or lay

Studies involving the use of the vaccine during early pregnancy were inconclusive, therefore vaccination is not recommended during the first 14 days of pregnancy. No safety study on the reproductive performance has been conducted in male rabbits (bucks).Therefore, the vaccination of breeding bucks is not recommended.


No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Amounts to be administered and administration route

After reconstitution, administer 1 dose of vaccine by subcutaneous injection to rabbits from 5 weeks of age onwards.

Revaccinate annually.

Ensure that the lyophilisate is completely reconstituted before use.

Single dose vial Reconstitute a single dose vial of vaccine with 1 ml of Nobivac Myxo RHD solvent and inject the total contents of the vial.

50 dose vial

Solvent volume

Number of vials of freeze-dried vaccine to be added

Injection volume

Total number of rabbits that can be vaccinated

10 ml


0.2 ml


50 ml


0.2 ml


For proper reconstitution of the multidose vial, use the following procedure:

•Add 1-2 ml of Nobivac Myxo RHD solvent to the 50 dose vaccine vial(s) and ensure that the lyophilisate is fully dissolved.

•Withdraw the reconstituted vaccine concentrate from the vial(s) and inject it back into the Nobivac Myxo RHD solvent vial.

•Ensure that the resulting vaccine suspension in the Nobivac Myxo RHD solvent vial is properly mixed.

•Use the vaccine suspension within 4 hours of reconstitution. Any reconstituted vaccine remaining at the end of this time should be discarded.


In addition to the signs observed after single dose vaccination, a mild swelling of the local lymph nodes may be observed within the first 3 days after overdose vaccination.

Withdrawal periods

Zero days.

Pharmacological particulars

Immunological properties

Pharmacotherapeutic group: live viral vaccine, ATCvet code: QI08AD.

To stimulate immunity against myxoma virus and rabbit haemorrhagic disease virus. The vaccine strain is a myxoma virus expressing the capsid protein gene of rabbit haemorrhagic disease virus. As a consequence rabbits are immunised against both myxoma virus and rabbit haemorrhagic disease virus. After infection with virulent myxoma virus some vaccinated animals may develop a few very small swellings, especially on hairless places of the body, which quickly form scabs.The scabs usually disappear within 2 weeks after the small swellings have been observed. These scabs are only observed in animals with active immunity and have no influence on the general health, appetite or behaviour of the rabbit.

Pharmaceutical particulars


Hydrolysed gelatine, Pancreatic digest of casein, Sorbitol, Disodium phosphate dihydrate, Potassium dihydrogen phosphate and Water for injections.

Major incompatibilities

Do not mix with any other veterinary medicinal product, except the solvent supplied for use with the vaccine.

Shelf life

Shelf-life of the lyophilisate as packaged for sale: 2 years.

Shelf-life of the solvent as packaged for sale: 1 ml and 10 ml Glass vials: 4 years.

50 ml PET vials: 2 years.

Shelf-life after reconstitution according to directions: 4 hours.

Special precautions for storage

Lyophilisate: Store in a refrigerator (2°C - 8°C). Do not freeze. Protect from light.

Solvent (50 ml PET vial): Store in a refrigerator (2°C - 8°C). Do not freeze.

Solvent (1 ml and 10 ml glass vial): No special precautions for storage. Do not freeze.

Immediate packaging

Lyophilisate: Glass vial of 1 or 50 doses with a halogenobutyl rubber stopper and aluminium cap.

Solvent: Glass vial of 1 ml or 10 ml, or polyethylene terephthalate (PET) bottle of 50 ml with a halogenobutyl rubber stopper and aluminium cap.

Packaging: Box with 5 x 1 dose vial of vaccine and 5 x 1 ml vial of solvent.

Box with 25 x 1 dose vial of vaccine and 25 x 1 ml vial of solvent.

Box with 10 x 50 doses vial of vaccine.

2 Boxes with 1 x 50 ml vial of solvent.

Box with 10 x 10 ml vial of solvent.

Not all pack sizes may be marketed.


Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities.

Marketing Authorisation Holder (if different from distributor)

Marketing authorisation number

EU/2/11/132/001 – 004.

Date of the first authorisation or date of renewal

7 September 2011

Date of revision of the text

7 September 2011

Any other information


Legal category


GTIN (Global Trade Item No)

Nobivac Myxo-RHD 5x1ds+5x1ml:


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Reviews of Nobivac Myxo-RHD Vaccine for Rabbits

Read our customers' reviews of Nobivac Myxo-RHD Vaccine for Rabbits

Questions & Answers for Nobivac Myxo-RHD Vaccine for Rabbits

Below are some recent questions we've received regarding Nobivac Myxo-RHD Vaccine for Rabbits, including answers from our team.

Ask Your Own Question


7th Jul 2016
Maureen Taylor
  • VioVet Customer Since: July 2016
  • From: Essex, United Kingdom

Does this product come supplied with syringes or do we need to purchase them separately ?

John Cousins
  • Veterinary Surgeon

Syringes and needles are not included, they must be bought separately. Each rabbit is normally vaccinated using a 1ml syringe, but a larger syringe can be used to add the solvent if the multidose size is being used. Needles I would recommend are often 23g x 5/8", which are available on the website.

New vaccine for RVHD-2 strain

2nd Jun 2016
Fiona Wase
  • VioVet Customer Since: February 2016
  • From: Powys, United Kingdom

HI will you be getting the new vaccine when it comes into the UK later this month please?

Also is the current myxo-VHD vaccine available in the 50 dose bottle at all?

John Cousins
  • Veterinary Surgeon

We buy our veterinary drugs through the standard veterinary wholesalers. We expect to be able to supply this new vaccine as soon as it is released to the wholesalers. The 50 dose pack is not listed by our wholesalers so we cannot supply it unfortunately.

Getting perscription

20th Feb 2014

Hi my question is how do you get the vet to give you a perscription for this ive had rabbits for 14yrs now and have done antibiotic injections for the rabbits but the vets seem very aprensive about giving a perscription for this i have 40 rabbits so is more cost effective to buy from here

John Cousins
  • Veterinary Surgeon

This is down to the discretion of your own vet. Your vet should legally provide a prescription on request if he/she feels that the medication is appropriate and you are competent to give it safely and effectively. If your vet has any doubts about those things, then your vet should not give you a prescription. Vets are in fact often influenced by the commercial aspects of handing out prescriptions - they make a lot of money from administering vaccinations themselves. This should not be part of their decision-making in fact, but they are human. You will need to discuss the whole issue with your vets and see what they say.