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Microbex Medicated Shampoo

Microbex Medicated Shampoo
200ml Bottle

  • 200ml Bottle £11.99

Description

Microbex Shampoo is used to treat skin conditions in dogs associated with bacterial or fungal overgrowth. This particularly includes proliferation of the yeast Malassezia pachydermatis and the bacterium Staphylococcus intermedius, which are commonly found in excessive numbers on dogs with itchy or sore skin. Microbex shampoo can help to control these clinical signs and restore the skin to good health.

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All prices include VAT where applicable.

Medication Datasheets

200ml Bottle

Microbex

Presentation

Shampoo.

Pink to orange clear solution, each ml of shampoo contains as active substance: chlorhexidine digluconate 31.2mg

Uses

For use in dogs for the treatment of Malassezia pachydermatis surface proliferation and the control of associated clinical signs.

Dosage and administration

Administer the shampoo topically three times a week for 2 weeks then, if necessary, twice a week for 2 weeks and finally on a weekly basis. If necessary, further use may be required in accordance with the directions of and a risk:benefit assessment by the prescribing veterinary surgeon.

Wet the animal thoroughly with clean water and apply the product to the animal at several points. Apply a quantity of product according to the dog’s weight and hair-coat length in order to develop lather. Distribute the product uniformly all over the surface of the hair and ensure that it is applied around the lips, under the tail and between the toes. Massage the animal’s body to develop lather and rinse immediately. Repeat the operation a second time but allow a 10-minute contact period before rinsing the hair coat with clean water. Leave the dog to dry naturally in a warm draught-free environment.

The following provides a guide to suitable volumes; however, the amount of the product to be administered has to be adapted to both, the size of the dog and the hair-coat length. The volume of the product applied should be sufficient to develop lather.

Bodyweight Volume of product

<4.9 kg 10 ml x 2 baths

5.0 to 10.9 kg 15 ml x 2 baths

11.0 to 15.9 kg 20 ml x 2 baths

16.0 to 20.9 kg 25 ml x 2 baths

21.0 to 30.9 kg 30 ml x 2 baths

31.0 to 45.9 kg 40 ml x 2 baths

>46.0 kg 50 ml x 2 baths

Contra-indications, warnings, etc

Special precautions for use in animals

For external use only.

In case of accidental contact with eyes, rinse with plenty of water.

This product should not be used in dogs that are known to be hypersensitive to chlorhexidine or any of the other ingredients. Safety of the product has not been demonstrated in animals of less than five months of age.

Do not allow the animal to lick itself during shampooing and rinsing or before it is dried. Take care to avoid the animal inhaling the product or getting it into the eyes, nose or mouth during shampooing.

Safety of the product has not been demonstrated beyond six weeks of use.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Handle this product with care if you know you are sensitised or if you have been advised not to work with such preparations. Avoid contact with eyes. In case of accidental eye contact, rinse with abundant quantities of water. In case of eye irritation, seek medical advice. Wash hands after use. Do not eat, drink or smoke while handling this product. In the event of accidental ingestion, seek medical advice and show the package insert or the label to the physician.

Adverse reactions (frequency and seriousness)

In a clinical trial, pruritus and erythematous reactions were common observations after shampooing with this product. In most cases, these reactions did not necessitate the cessation of treatment and clinical signs resolved completely without any specific therapy. However, if signs persist, the veterinary surgeon should re-evaluate the treatment.

Conjunctival inflammation may occur and usually resolves without treatment.

Use during pregnancy, lactation or lay

Laboratory studies in rats and dogs have not produced any evidence of teratogenic, foetotoxic or maternotoxic effects due to chlorhexidine. However, the safety of the product in dogs has not been investigated during pregnancy and lactation. Therefore, use in accordance with a benefit/risk assessment by the responsible veterinarian.

Puppies should not come into contact with nursing females after treatment until the coat has dried.

Interaction with other medicinal products and other forms of interaction

Frequent shampooing may reduce the efficacy of other topically-applied products, e.g. ectoparasiticides.

No data are available to evaluate interactions with other topically-applied products.

Overdose (symptoms, emergency procedures, antidotes), if necessary

A tolerance study performed in dogs receiving up to five times the recommended therapeutic dose, three days a week for four consecutive weeks, showed on occasions slight cutaneous reactions only. These reactions were transient, although they could last for several days when shampooing was ongoing. They did not require any specific treatment.

Pharmaceutical precautions

Keep out of the reach and sight of children.

Shelf life of the veterinary medicinal product as packaged for sale: 3 years.

Shelf life after first opening the immediate packaging: 2 months.

Special precautions for storage

This veterinary medicinal product does not require any special storage condition.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

Packaging quantities

Carton box containing one 200-ml white high-density polyethylene bottle closed by a polypropylene disc top screw and an overcap.

Further information

Chlorhexidine digluconate is an antiseptic agent of the biguanine group with a broad-spectrum bactericidal activity against gram-positive and gram-negative bacteria as well as a fungicidal activity against yeasts.

The mode of action of chlorhexidine (i.e. whether it is bactericidal or bacteriostatic) depends on the concentration used. Chlorhexidine alters the permeability of the bacterial-cell wall. At low concentrations, low molecular-weight substances leak out without the cell being irreversibly damaged. At higher concentrations, chlorhexidine enters the cell, causes precipitation of the cytoplasm, prevents repair to the bacterial-cell membrane and causes the destruction of the bacterial cell.

Typical MIC values found in clinical Malassezia pachydermatis isolates are 2-4 µg/ml (2008).

To date (2009) no resistance to chlorhexidine has been shown for Malassezia pachydermatis.

Resistance to chlorhexidine is uncommon in Gram (+) bacteria but some resistant Gram (-) isolates have been described in human hospital environments (Proteus spp., Pseudomonas spp.).

When used in accordance with the recommended dose regimen the development of resistance to chlorhexidine is not expected.

After topical administration of the product to dogs, there was little or no systemic absorption of chlorhexidine digluconate. Absorption of chlorhexidine after oral administration is also very low. The efficacy of the product is due to the high concentrations of chlorhexidine digluconate achieved on the body surface for the 10-minute period of shampooing.

Marketing Authorisation Number

Vm 05653/4143

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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