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Loxicom Oral for Dogs & Cats

Loxicom Oral for Dogs & Cats
1mg Chewable Tablets » Priced per Tablet

  • 1mg Chewable Tablets » Priced per Tablet £0.49
  • 2.5mg Chewable Tablets » Priced per Tablet £0.89
  • Cats » 5ml Bottle £8.99
  • Cats » 15ml Bottle £14.50
  • Dogs » 10ml Bottle £7.00
  • Dogs » 15ml Bottle £13.00
  • Dogs » 32ml Bottle £14.99
  • Dogs » 100ml Bottle £37.99

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Description

Loxicom is supplied as a liquid to add to food or as tablets. It contains the well known and trusted veterinary drug meloxicam. This is a non-steroidal anti-inflammatory drug which is used to provide relief from the stiffness and discomfort associated with osteoarthritis in the dog and cat. It is also used for other painful, inflammatory conditions, especially of the musculo-skeletal system, such as injuries. It can be given for a short course in acute conditions, or can be given for long periods of time in chronic conditions.

Alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders in dogs Do not use in pregnant or lactating animals.
Initial treatment is a single dose of 0.2mg meloxicam/kg bodyweight (i.e.1.33ml/10 kg bodyweight) on the first day. Treatment is to be continued once daily by oral administration (at 24 hour interval) at a maintenance dose of 0.1mg meloxicam/kg bodyweight (i.e. 0.667ml/10kg bodyweight).
For longer term treatment, once clinical response has been observed (after 4 days), the dose can be adjusted to the lowest effective individual dose reflecting that the degree of pain and inflammation associated with chronic musculo-skeletal disorders may vary over time.
Particular care should be taken with regard to the accuracy of dosing. Please carefully follow the instructions of the veterinarian.
For oral use. To be administered with food or directly into the mouth. shake well before use.
The suspension can be given using either of the two measuring syringes provided in the package. The syringes fit onto the bottle and have a kg-bodyweight scale which corresponds to the maintenance dose (i.e. 0.1mg meloxicam/kg bodyweight). Thus for initiation of the therapy on the first day, twice the maintenance volume will be required.
A clinical response is normally seen within 3-4 days. Treatment should be discontinued after 10 days at the latest if no clinical improvement is apparent. Avoid introduction of contamination during use.
Each ml contains: Meloxicam 1.5mg/ml Sodium benzoate 1.5mg
Do not use in pregnant or lactating animals. Do not use in animals suffering from gastrointestinal disorders such as irritation and haemorrhage, impared hepatic, cardiac or renal function and haemorrhagic disorders. Do not use in case of hypersensitivity to the active substance or to any of the excipients. Do not use in dogs less than 6 weeks of age. Typical adverse reactions of non-steroidal anti-inflammatory drugs (NSAIDs) such as loss of appetite, vomiting, diarrhoea, faecal occult blood, apathy and renal failure have occasionally been reported. These adverse reactions occur generally within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal. If adverse reactions occur, treatment shoud be discontinued and the advice of a veterinarian should be sought. Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of renal toxicity. Other NSAIDs, diuretics, anticoagulants, aminoglycoside antibiotics and substances with high protein binding may compete for binding and thus lead to toxic effects. Loxicom must not be administered in conjunction with other NSAIDs or glucocorticosteroids. Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such veterinary medicinal products should be observed for at least 24 hours before commencement of treatment. The treatment-free period, however, should take into account the pharmacokinetic properties of the products used previously. In the case of overdose symptomatic treatment should be initiated.

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Medication Datasheets

Dogs » 100ml Bottle

Loxicom 1.5 mg/ml Oral Suspension Dogs

Qualitative and quantitative composition

Each ml contains:

Active Substance: Meloxicam 1.5 mg

Excipients: Sodium Benzoate 1.5 mg

Pharmaceutical form

Pale yellow oral suspension.

Clinical particulars

Target species

Dogs.

Indications for use, specifying the target species

Alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders in dogs.

Contraindications

Do not use in pregnant or lactating animals.

Do not use in animals suffering from gastrointestinal disorders such as irritation and haemorrhage, impaired hepatic, cardiac or renal function and haemorrhagic disorders.

Do not use in case of hypersensitivity to the active substance or to any of the excipients.

Do no use in dogs less than 6 weeks of age.

Special warnings for each target species

None.

Special precautions for use

Special precautions for use in animals

If adverse reactions occur, treatment should be discontinued and the advice of a veterinarian should be sought.

Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of renal toxicity.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

People with known hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) should avoid contact with the veterinary medicinal product.

In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions (frequency and seriousness)

Typical adverse reactions of NSAIDs such as loss of appetite, vomiting, diarrhoea, faecal occult blood, apathy and renal failure have occasionally been reported. In very rare cases haemorrhagic diarrhoea, haematemesis, gastrointestinal ulceration and elevated liver enzymes have been reported. These adverse reactions occur generally within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.

Use during pregnancy, lactation or lay

The safety of the veterinary medicinal product has not been established during pregnancy and lactation

Interaction with other medicinal products and other forms of interaction

Other NSAIDs, diuretics, anticoagulants, aminoglycoside antibiotics and substances with high protein binding may compete for binding and thus lead to toxic effects. Loxicom must not be administered in conjunction with other NSAIDs or glucocorticosteroids.

Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such veterinary medicinal products should be observed for at least 24 hours before commencement of treatment. The treatment-free period, however, should take into account the pharmacokinetic properties of the products used previously.

Amounts to be administered and administration route

Oral use.

To be administered with food or directly into the mouth.

Shake well before use.

Initial treatment is a single dose of 0.2 mg meloxicam/kg bodyweight (i.e. 1.33 ml/10 kg bodyweight) on the first day. Treatment is to be continued once daily by oral administration (at 24 hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg bodyweight (i.e. 0.667 ml/10 kg bodyweight).

For longer term treatment, once clinical response has been observed (after ≥ 4 days), the dose can be adjusted to the lowest effective individual dose reflecting that the degree of pain and inflammation associated with chronic musculo-skeletal disorders may vary over time.

Particular care should be taken with regard to the accuracy of dosing.

The suspension can be given using either of the two measuring syringes provided in the package (depending on weight of dog). The syringes fit onto the bottle and have a kg-bodyweight scale which corresponds to the maintenance dose (i.e. 0.1 mg meloxicam/kg bodyweight). Thus for the first day, twice the maintenance volume will be required. Alternatively therapy may be initiated with Loxicom 5 mg/ml solution for injection.

A clinical response is normally seen within 3-4 days. Treatment should be discontinued after 10 days at the latest if no clinical improvement is apparent.

Avoid introduction of contamination during use.

Overdose (symptoms, emergency procedures, antidotes), if necessary

In the case of overdose, symptomatic treatment should be initiated.

Pharmacological particulars

Pharmacotherapeutic Group: Anti-inflammatory and anti-rheumatic products, non-steroids (oxicams).

ATCvet code: QM01AC06

Pharmacodynamic properties

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, anti-exudative and antipyretic effects. It reduces leukocyte infiltration into the inflamed tissue. To a minor extent it also inhibits collagen-induced thrombocyte aggregation. In vitro and in vivo studies demonstrated that meloxicam inhibits cyclooxygenase-2 (COX-2) to a greater extent than cyclooxygenase-1 (COX-1).

Pharmacokinetic particulars

Absorption

Meloxicam is completely absorbed following oral administration and maximal plasma concentrations are obtained after approximately 4.5 hours. When the product is used according to the recommended dosage regime, steady state concentrations of meloxicam in plasma are reached on the second day of treatment.

Distribution

There is a linear relationship between the dose administered and plasma concentration observed in the therapeutic dose range in dogs. Approximately 97 % of meloxicam is bound to plasma proteins. The volume of distribution is 0.3 l/kg.

Metabolism

Meloxicam is predominantly found in plasma and is also a major biliary excretion product whereas urine contains only traces of the parent compound. Meloxicam is metabolised to an alcohol, an acid derivative and to several polar metabolites. All major metabolites have been shown to be pharmacologically inactive.

Elimination

Meloxicam is eliminated with a half-life of 24 hours. Approximately 75 % of the administered dose is eliminated via faeces and the remainder via urine.

Pharmaceutical particulars

List of Excipients

Sodium Benzoate

Glycerol

Povidone K30

Xanthan Gum

Disodium Phosphate Dihydrate

Sodium Dihydrogen Phosphate Dihydrate

Citric Acid Anhydrous

Simethicone Emulsion

Purified water

Incompatibilities

None known.

Shelf-life

Shelf-life of the veterinary medicinal product as packaged for sale: 18 months

Shelf-life after first opening the immediate packaging: 6 months

Special precautions for storage

This veterinary medicinal product does not require any special storage conditions.

Nature and composition of immediate packaging

The veterinary medicinal product is presented in 10 ml, 32 ml, 100 ml and 2 x100ml polyethylene screw bottles with HDPE/LDPE child resistant caps. Two polyethylene/polypropylene measuring syringes, a 1 ml and 5 ml syringe, are supplied with each bottle to ensure accurate dosing of small and large dogs.

Each syringe is graduated in bodyweight, the 1 ml syringe is graduated from 0.5 kg to 15 kg and the 5 ml syringe for 2.5 kg to 75 kg.

Special precautions for the disposal of unused veterinary medicinal product or waste material derived from the use of such products

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Marketing Authorisation Holder (if different from distributor)

Station Works

Newry

Co Down, BT35 6JP

United Kingdom

Marketing Authorisation Number

EU/2/08/090/003

EU/2/08/090/004

EU/2/08/090/005

EU/2/08/090/032

Date of the first authorisation or date of renewal

Date of first authorisation: 10/02/2009

Date of last renewal: 12/03/2014

Date of revision of the text

Detailed information on this veterinary medicinal product is available on the website of the European

Medicines Agency http://www.ema.europa.eu/.

Any other information

Legal category

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (24)

Q & A

Below are some recent questions we've received regarding Loxicom Oral for Dogs & Cats, including answers from our team.

6 July 2016 at 4:31pm

Would a joint supplement be helpful?

Louise

  • VioVet customer since 2014
  • From: Cambridgeshire, United Kingdom

My 12 yr old staffie has been prescribed loxicom for arthritis, would joint supplements such as cod liver oil or similar help him at all and can they be taken together

  • Non-Executive Director

Loxicom belongs to a group of drugs (the so called NSAIDs) which are often used alongside a joint supplement. It is widely believed that the combination is helpful, though scientific support for this is not totally conclusive. The most highly regarded joint supplements contain glucosamine, chondroitin and some other ingredients. Good examples would be Yumove and Joint Force. I would recommend you give one of these rather than cod liver oil. They need to be given for a few weeks before you can expect to see full results, because they are nutritional supplements rather than drugs, so their effects tend to take a while to build up. Some dogs do seem to respond remarkably well, others minimally, but you only find out by trying.

14 October 2015 at 5:30am

Getting prescription

Barney

How do I get a prescription &how much will my vet charge

  • Non-Executive Director

As soon as your vet has decided which medication is best for your pet, you can ask him or her to give you a written prescription for that medication. It is that piece of paper which we need a copy of before we can sell you the medication. It is entirely up to your vet how much they charge for writing it out. Most vets charge between £5 and £15, though a few vets do not charge at all. They are also able to write the prescription for just one small bottle, or multiple bottles to last you 6 months or a year if they feel the medication will be needed for that long. We can then keep a copy of the prescription and you can buy new bottles when you need them. That way you pay just one prescription fee for multiple bottles. It all depends how helpful your vet is - they vary a lot.

9 September 2015 at 4:53pm

Dose

Catherine

Is 0.1mg/kg the most a dog can have. My rotti has a osteosarcoma and is for palliative care. Currently taking 0.1mg/kg but was wondering if he can have more.

  • Non-Executive Director

Some dogs can tolerate a higher dose, others will react badly (maybe after a while as the drug builds up in the body) and suffer serious side effects (usually gastro-intestinal upset with bleeding etc, but maybe liver/kidney trouble). I am afraid that the outlook for your dog is clearly not good anyway, so you will of course just want to do what you can to make things less uncomfortable. Usually this would be achieved by adding other classes of pain-relieving medication to the Loxicom, rather than pushing the dose of Loxicom to potentially problematic levels. Your vet could prescribe other medicines to add so I would definitely do that first. (If you can get a written prescription we sell many other things very economically, but they must be prescribed by your own vet.)

25 August 2015 at 6:39pm

Side effects

Lorraine

Hello my dog has renal problems and is managed on a special diet, recently he has developed joint problems, following x-rays he was prescribed loxicom, I am concerned about the effects this drug might have on his kidneys, I am aware that unfortunately wanting to keep him pain free means we have to give him something. Is this drug particularly tough on the kidneys? Thankyou for your help.

  • Non-Executive Director

You are right to be mindful of the issues here, but there is not a perfect answer. Loxicom contains the drug meloxicam and this probably provides the best balance between good pain relief combined with minimal adverse effect on the kidneys. You should not exceed the recommended dose and if possible, judging on results, you might try to reduce the dose of Loxicom in time. Obviously talk to your own vet about this, but for many dogs in this situation, this is a perfectly reasonable choice. If your dog becomes ill in any way, especially if he goes off his food or shows vomiting or diarrhoea, then you should stop Loxicom until things are better.

23 September 2014 at 4:36pm

Why did my vet not tell me about this.

susan

my GSD just got spayed on Friday n my vet charged me £15 for 1.5 mg/ml bottle of loxicom and today I had to buy another one as she is still swollen, In future how would I go about askn for a prescription to buy online as its so much cheaper for me. ty x

  • Non-Executive Director

You can at any time ask your vet for a written prescription from him/her in order to buy medication elsewhere. Your vet will be familiar with this sort of request. He/she is obliged to give you a prescription on request if the medication is suitable, but can and normally will charge you for the document (say £10 or £15). That can mean that it is not worth buying the medication elsewhere, but it depends how helpful your vet wants to be. Some do not charge at all. Usually the system works best for animals which are on long-term medication for arthritis or heart disease etc and you can buy 6 months worth of meds on one prescription.

20 September 2014 at 1:13pm

Poor response to treatment?

how long t see improvement and

How long does it take t show improvement my dog has had injection and one dose but still squeling out in pain and cant move how long leave him before consulting vet again

  • Non-Executive Director

It sounds as if your dog might be in severe pain and the treatment is not being effective. Some causes of pain do not respond well to this drug anyway, so I think you should go back to your vet and get things re-assessed.