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An injectable solution containing nitroxynil eglumine for use in cattle and sheep against immature and mature liver fluke. POM-VPS.
Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication.
Company name: Merial Animal Health Ltd
Address: PO Box 327
Harlow Business Park
Essex CM19 5TG
Telephone: Companion Animals 0870 6000123
Production Animals 0800 592699
Fax: 01279 775888
Email: [email protected]
Solution for injection. Clear, orange-red solution containing nitroxynil (as N-ethylglucamine salt) 34% w/v.
TRODAX 34% solution is indicated for the treatment of fascioliasis (infestations of mature and immature Fasciola hepatica) in cattle and sheep. It is also effective, at the recommended dose rate, against adult and larval infestations of Haemonchus contortus in cattle and sheep and Haemonchus placei, Oesophagostomum radiatum and Bunostomum phlebotomum in cattle. However, TRODAX 34% should not be regarded or used as a broad spectrum anthelmintic.
Administer by subcutaneous injection.
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.
The standard dosage is 10mg nitroxynil per kilogram bodyweight.
Sheep: Administer according to the following doses scale:
|Liveweight (kg)||Dose (ml)|
On farms with fluke-infested pastures, routine dosing should be carried out at intervals of not less than 49 days (7 weeks), having regard for such factors as the past disease history of the farm, the frequency and severity of neighbouring outbreaks and regional forecasts of incidence.
In outbreaks of acute fascioliasis advice on the best treatment should be sought from a veterinary surgeon.
Cattle: 1.5ml of TRODAX 34% per 50kg (1cwt) liveweight.
Both infected and in-contact animals should be treated, treatment being repeated as considered necessary, though not more frequently than once per 60 days. The treatment of cattle helps reduce contamination of pastures on farms where fascioliasis is endemic or certain roundworm occurrence is evident.
For animal treatment only.
Do not use in animals with known hypersensitivity to the active ingredient.
Do not exceed stated dose.
Small swellings are occasionally observed at the injection site in cattle. These can be avoided by injecting the dose in two separate sites and massaging well to disperse the solution.
No systemic ill effects are to be expected when animals (including pregnant cows and ewes) are treated at normal dosage.
Ensure the injection does not enter subcutaneous muscle.
Ewes in advanced pregnancy should be handled and dosed carefully.
Estimate the weight of the sheep carefully and use injection equipment calibrated to accurately deliver the calculated dosage.
TRODAX 34% solution stains and care should be taken not to spill it, especially on the fleece of sheep.
In the event of accidental overdose, the symptoms are pyrexia, rapid respiration and increased excitability. Patients should be kept cool, and dextrose saline should be administered intravenously.
Do not retreat at intervals less than 60 days (cattle) or 49 days (sheep).
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
· Too frequent and repeated use of anthelmintics from the same class, over an extended period of time
· Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
To date, no resistance to nitroxynil has been reported. The use of the product should be based on local (regional, farm) epidemiological information about susceptibility of trematodes and nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Wear impermeable gloves to avoid staining the skin. Wash splashes from skin and eyes immediately.
Obtain medical help if irritation persists.
In case of accidental or deliberate ingestion, wash out the mouth with water and obtain medical help.
Care must be taken to avoid accidental self-injection. Seek medical assistance in case of accidental injection.
Cattle may be slaughtered for human consumption only after 60 days from the last treatment. Sheep may be slaughtered for human consumption only after 49 days from the last treatment. Not permitted for use in animals producing milk for human consumption, including pregnant animals intended to produce milk for human consumption.
Do not dilute or mix with other compounds.
Once the container has been broached, the contents should be used within 28 days.
This product does not contain a preservative.
Avoid the introduction of contamination. Should any apparent growth or discoloration occur, the product should be discarded.
Do not store above 25°C, protect from light.
Keep out of the reach and sight of children.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Multi-dose containers of 250 ml and 2x500ml.
Nitroxynil is active against triclabendazole-resistant Fasciola hepatica.
No signs of incompatibility are to be expected if TRODAX 34% is administered to cattle or sheep concurrently with therapeutic doses of levamisole, or with clostridial vaccine.
TRODAX 34% is safe for use in pregnant animals.
All prices include VAT where applicable.
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Below are some recent questions we've received regarding Liver Wormer Trodax 34% for Cattle & Sheep, including answers from our team.
Is 18 ml the maximum dose for cattle even if an animal weighs 700kg ?
The dose rate for cattle is 1.5mls per 50kg bodyweight, so a 700kg animal would need 21mls. There is a meat withdrawal period of 60 days from the last treatment.