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A palatable, aniseed flavoured aqueous fenbendazole suspension for oral administration. Lapizole is a broad-spectrum, oral anti-parasiticide for administration in the prevention and treatment of infections caused by internal parasites of rabbits, ferrets, birds, reptiles including Encephalitozoon cuniculi.

Lapizole® 20 mg/ml Suspension for Oral Administration

Species: Ornamental birds, Pigeons, Rabbits, Reptiles, Ferrets Therapeutic indication: Antiprotozoals Active ingredient: Fenbendazole Product:Lapizole® 20 mg/ml Suspension for Oral Administration Product index: Lapizole 20 mg/ml Suspension for Oral Administration Withdrawal notes: For pet animals only. Do not use in animals intended for human consumption. Do not eat the eggs of treated birds. Notes: Small Animal Exemption Scheme (SAES) product

Qualitative and quantitative composition

1 ml suspension contains: Active substance: Fenbendazole 20 mg

Pharmaceutical form

Suspension for oral administration.

Clinical particulars

Target species

Rabbits, birds, reptiles and ferrets.

Indications for use

Broad spectrum de-wormer/anti-parasiticide. For oral administration in the prevention and treatment of infections caused by internal parasites, including Encephalitozoon cuniculi.

Contraindications

Lapizole is only for use in rabbits, birds, reptiles and ferrets. Do not use in animals other than those indicated. Do not use in pregnant animals. Do not overdose.

Special warnings for each target species

In birds, fenbendazole can cause intestinal problems and inhibit bone marrow production. Do not use in nestlings/growing birds or those in moult. In some mammalian species, high doses of fenbendazole can lead to bone marrow suppression, gastrointestinal tract irritation and problems in pregnancy. Do not overdose. As with all veterinary medicines, occasional instances of allergic response due to prior sensitisation, drug intolerance and idiosyncratic reactions may occur.

Special precautions for use

For animal treatment only. If you are uncertain about the condition of your pet, consult a veterinary surgeon. If symptoms persist, consult a veterinary surgeon.

Special precautions to be taken by the person administering the product to animals

Avoid contact with the skin. Wash hands with soap and water following treatment.

Use during pregnancy and lactation

No data available. Do not use in pregnant animals.

Interactions

None known.

Amounts to be administered and administration route

Suspension for oral administration. Weigh animal carefully before administration to accurately assess the appropriate dose. Shake the bottle well before each daily administration. Using the easy dose syringe: Remove the cap and peel off the foil bottle covering. Place the plastic plug into the neck of the bottle. Push the syringe firmly into the plug (hole) in the neck of the bottle. Turn the bottle upside down. Whilst holding the syringe in place, gently pull the plunger, drawing the liquid to the correct mark on the syringe. Turn the bottle the right way up and remove the syringe from the plug by gently twisting the syringe. After use, replace the cap. Wash the syringe in warm water and allow to dry. (Please refer to dosing guide).
Treatment/prevention of E. Cuniculi Fenbendazole dose rate Volume of Lapizole to administer
Rabbits 20 mg/kg daily for 28 days 0.1 ml per 100 g (1 ml per kg) daily for 28 days
Worming by species Fenbendazole dose rate Volume of Lapizole to administer
Use where faecal screening for parasites is positive Use with caution, or delay treatment, in clinically sick animals
Rabbits 20 mg/kg daily for 5 days 0.1 ml per 100 g daily for 5 days
Ferrets 20 mg/kg daily for 5 days 0.1 ml per 100 g daily for 5 days
Pigeons 10 mg/kg once daily for 3 days For an average sized 400 g adult pigeon: 0.2 ml once daily for 3 days
Psittacines and passerines 20 mg/kg once daily for 3 days 0.1 ml per 100 g once daily for 3 days
Raptors 20 mg/kg once daily for 5 days 0.1 ml per 100 g once daily for 5 days
Reptiles - lizards and snakes 25 mg/kg once daily for 3 days 0.125 ml per 100 g once daily for 3 days
Reptiles - tortoises Single dose of 50 mg/kg Repeat as necessary based on faecal parasitology in 3 weeks 0.25 ml per 100 g

Withdrawal period

For pet animals only. Do not use in animals intended for human consumption. Do not eat the eggs of treated birds.

Pharmaceutical particulars

Incompatibilities

None known.

Special precautions for storage

Do not store above 25°C. Do not freeze. Protect from direct sunlight. Keep out of the sight and reach of children. No in-use shelf life studies have been undertaken on this product.

Immediate packaging

Polypropylene container containing 100 ml of suspension and a dosing syringe.

Disposal

Dispose of waste material in accordance with local requirements.

WDA 1732

Further information

Encephalitozoon cuniculi is a protozoal parasite of rabbits which affects the nervous and urinary systems and can cause a number of clinical signs. These include, but are not limited to, head tilt, hind limb paralysis or weakness, eye problems and death. It is a common parasite which is frequently sub-clinical, but in one study over 50% of rabbits in the UK were shown to have been infected. Encepalitozoon cuniculi may be passed on to humans and presents a potential risk to individuals who may have deficiencies to the immune system. Date of last review: May 2013

Legal category

Legal category: SAES

GTIN

GTIN description:Lapizole 20 mg/ml Suspension for Oral Administration 100 ml: GTIN:05060019580639

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