UK Registered Veterinary Retailer
Lactovac for Cows
25ml Bottle (5 doses)

  • 25ml Bottle (5 doses) £60.49


Lactovac is used to immunise cows so that passive immunity is transferred to their calves (through the colostrum) to protect agaisnt the major causes of calf diarrhoea

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  • Landline: 01582 842096
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  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

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Medication Datasheets

25ml Bottle (5 doses)

Lactovac suspension for injection


A suspension for injection, each 5 ml contains:

Inactivated bovine rotavirus, strain 1005/78 at least 107.4 TCID50* inducing ≥ 1 RPU***
Inactivated bovine rotavirus, strain Holland at least 107.0 TCID50* inducing ≥ 1 RPU***
Inactivated bovine coronavirus, strain 800 at least 105.8 TCID50* inducing ≥ 1 RPU***
Inactivated E. coli K99/F41, strain S1091/83 250-260 HAU** inducing ≥ 1 RPU***

Each dose also contains aluminium hydroxide (60 mg) and saponin/Quil A (1 mg) as adjuvants and thiomersal (0.05 mg) as preservative.

* Tissue culture infective dose

** Haemagglutinating units

*** Relative potency unit; 1 RPU = antibody response in rabbit potency test not significantly lower than that obtained with a reference batch shown efficacious in cattle.


For the active immunisation of pregnant cows and heifers in order to confer passive protection to their calves (via colostrum) to reduce the severity and duration of neonatal diarrhoea caused by rotavirus, coronavirus and E. coli infections.

Protection is conferred only while the calves are fed colostrum from vaccinated cows.

Dosage and administration


5 ml by subcutaneous injection in the side of the neck, observing aseptic precautions.

Vaccination schedule

All cows in a herd should receive two injections of 5 ml during the later stages of pregnancy, with an interval of 4-5 weeks between doses and allowing 2-3 weeks from the time of the second dose until the predicted date of calving.

Booster injection

During each subsequent pregnancy previously vaccinated cows should receive a single injection of 5 ml 2-6 weeks prior to predicted calving date.

Passive immunisation

In order to attain local passive immunisation within the intestine against neonatal diarrhoea, the newborn calves must receive sufficient quality colostrum and milk from the vaccinated dams during the first 10 to 14 days of life. For calves born to beef cows this can be achieved by allowing the calf to suckle naturally. Calves born to dairy cows often do not receive sufficient colostrum if suckled naturally, so artificial feeding of colostrum (e.g. via oesophageal tube feeders) should be used.

Feeding and storage of colostrum

For optimal protection it has been shown that daily intake of colostrum is essential to the calf from birth to 2 weeks of age. All calves should be fed colostrum derived from the first milking, ideally within the first 6 hours of life. Calves should then either be left to suckle naturally for a minimum of 2 weeks or a colostrum feeding regime must be established. Any remaining quantities from the first milking and all the colostrum from the second milking should be pooled, aliquoted and stored deep frozen (-20ºC for a maximum of one year). Alternatively, these colostrum pools can be stored at about +4°C for about 2 weeks. Following the first suckling of colostrum from the dam by the calves, where the calves are separated from the dam, their feed must be supplemented with 500ml of pooled colostrum each day.

Contra-indications, warnings, etc

Do not use in animals which have intercurrent infection or are in poor nutritional status.

Immunisation may rarely result in temporary swellings at the injection site (ranging from small nodules of approximately 1 cm in diameter to swellings of 20 cm diameter in extreme cases). Typically, these swellings completely disappear or reduce to a negligible size within 2-4 weeks after vaccination, though in individual animals very small reactions remain longer. Additionally, a transient slight rise in body temperature normally decreasing to a non-significant level within one day may be expected.

The frequency of adverse reactions is defined using the following convention:

Only vaccinate immuno-competent animals.

Can be used during pregnancy.

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Do not mix with any other veterinary medicinal product.

Withdrawal period

Zero days

User warnings

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. People with known hypersensitivity to any of the components of the product should administer the product with caution.

Pharmaceutical precautions

Store in a refrigerator (+2°C to +8°C). Protect from frost.

Shelf-life after first opening the immediate package: 10 hours.

Keep out of the sight and reach of children.

For animal treatment only.

Legal category

Packaging quantities

Cardboard box containing a 25 ml glass vial or 10 x 5 ml glass vials. Not all pack sizes may be marketed.

Further information

Protection of the herd

Neonatal diarrhoea in calves is caused by pathogens which are constantly present in the herd. For this reason proper control measures require that all pregnant cows and heifers in a herd must be included in the programme of immunisation. This is the only way in which the pressure of infection can be reduced.

Herd hygiene

Neonatal diarrhoea in calves is often associated with poor hygiene. Thus, general improvements in hygiene are important to support the effect of vaccination.

Immune protection

Diarrhoeal diseases can have many causes. The vaccine induces high levels of antibody in the colostrum and milk against rotavirus and coronavirus as well as against E. coli, i.e. against the principal pathogens of neonatal diarrhoea in calves.

The feeding of pooled colostrum is recognised as a potential factor in the spread of Johne’s disease. Please discuss with your veterinary surgeon if you are concerned.


Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Marketing Authorisation Number

Vm 42058/4075

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.


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