For the treatment and control of gastro-intestinal nematodes, lungworms, warbles, chorioptic and sarcoptic mange and sucking and biting lice of beef and non lactating dairy cattle. POM-VPS.
Active substance: Ivermectin: 5 mg per ml.
For the full list of excipients, see below.
For the treatment and control of gastrointestinal nematodes, lungworms, eyeworms, warbles, chorioptic and sarcoptic mange and sucking and biting lice in beef and non-lactating dairy cattle.
The product at the recommended dosage level of 500 μg ivermectin per kg bodyweight effectively controls the following parasites of cattle:
Warbles (parasitic stages)
Sarcoptes scabiei var. bovis
The product given at the recommended dosage of 500 μg/kg bodyweight, controls infections with Trichostrongylus axei and Cooperia spp. acquired up to 14 days after treatment, Ostertagia ostertagi and Oesophagostomum radiatum acquired up to 21 days after treatment, and Dictyocaulus viviparus (lungworm) acquired up to 28 days after treatment. It also controls horn fly (Haematobia irritans) for up to 35 days after treatment.
To obtain optimal benefit from the persistent activity of the product for grazing animals it is recommended that calves which are set-stocked in their first grazing season should be treated 3, 8 and 13 weeks after the day of turnout. Studies have demonstrated that first-season grazing calves turned out to pasture in late April or May and treated with the product 3, 8 and 13 weeks after turnout can be protected from parasitic gastroenteritis and lungworm disease throughout the grazing season, provided they are set-stocked, all calves are included in the programme and that no untreated cattle are added to the pasture. Treated calves should also be monitored according to good husbandry practices.
The product has been formulated for topical application specifically in cattle. It should not be applied or administered to other species as severe adverse reactions, including fatalities in dogs, may occur. Do not apply to areas of skin which have mange, scabs or other lesions or to areas contaminated with mud or manure.
Rainfall before or after treatment will not affect the efficacy of the product. Do not apply to areas of skin which may have mange, scabs or other lesions or to areas contaminated with mud or manure. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
-Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
-Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to macrocyclic lactones (which includes ivermectin) has been reported in Cooperia spp. in cattle within the EU. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
For external use only.
HIGHLY FLAMMABLE – KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME OR OTHER SOURCES OF IGNITION.
May be irritating to human skin and eyes and the user should be careful not to apply it to himself or other persons. Operators should wear rubber gloves and boots with a waterproof coat when applying the product. Wash all protective clothing after use. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with copious water and get medical attention.
Do not smoke or eat while handling the product. Wash hands after use.
Use only in well-ventilated areas or outdoors.
Undesirable effects are not expected when the product is used at the recommended dose rate.
The product can be administered to beef cows at any stage of pregnancy or lactation provided that the milk is not intended for human consumption. It will not affect the fertility of cows and bulls and can be given to all ages of animals including young calves. Please also refer to ‘Special warnings for each target species’.
Not known. May be used concurrently with foot and mouth disease vaccine or clostridial vaccine.
Dosage: 1 ml per 10 kg bodyweight (based on a recommended dosage level of 500 μg/kg bodyweight).
Administration: The formulation should be applied along the mid-line of the back in a narrow strip between the withers and tailhead. To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Squeeze-Measure-Pour System (250 ml bottle and 1 litre pack)
•Attach the metering cup firmly to the bottle.
•Set the dose by turning the top section of the cup to align the correct bodyweight with the pointer on the knurled cap of the cup. When bodyweight is between markings, use the higher setting.
•Hold the bottle upright and squeeze it to deliver a slight excess of the required dose as indicated by the calibration lines.
•When the pressure is released, the dose automatically adjusts to the correct level. Tilt the bottle and dispense the solution.
•NOTE – FOR 1 LITRE BOTTLE AND 50 ML DIAL-A-DOSE CAP. When the 100 kg (10 ml) or 150 kg (15 ml) dose is required:
-turn cap to 10 ml or 15 ml mark
-squeeze bottle and fill to mark
-turn the pointer to “STOP” before dispensing the dose.
•The STOP position will close the system.
•Important – Keep upright when filling and during storage.
•Close container when not in use.
Collapsible Pack (2.5 litre pack x 2 in a carton)
If the carton is opened for purpose of sale in single 2.5 L units, a package insert must be provided with each transaction. Connect the pour-on applicator to the collapsible pack as follows:
•Attach the open end of the draw-off tubing to the pour-on applicator.**
•Attach draw-off tubing to the cap with the stem. Replace the shipping cap with the cap that has the draw-off tubing. Tighten this draw-off cap.
•Gently prime the pour-on applicator, checking for leaks.
•Follow manufacturer’s directions for correct use and care of the equipment.
** An applicator compatible with the formulation is available for use with the 2.5 litre pack of IVOMEC Pour-On. Other applicators may be incompatible with the formulation, resulting in locking, incorrect dosage and leakage.
No sign of toxicity appeared in trials up to 5 mg/kg (10 times the recommended dose rate). No antidote has been identified.
Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 15 days from the last treatment.
Do not use in cows producing milk for human consumption. Do not use in non-lactating dairy cows including pregnant heifers within 60 days of calving.
Triethanolamine, Isopropyl alcohol, Crodamol Cap.
No major incompatibility has been identified.
Shelf life of the product as packaged for sale: 3 years.
Avoid extremes of temperature. Protect from light. Store in tightly closed original container.
If stored below 0 °C, Ivomec Classic Pour-On may appear cloudy. Allowing the product to warm at room temperature will restore the normal appearance without affecting efficacy.
1 litre squeeze-measure-pour bottle, 2.5 litre high density collapsible backpacks. Not all pack sizes may be marketed
Any unused product or waste materials derived from such products should be disposed of in accordance with local requirements.
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container.
Ivomec Classic Pour-On for Cattle 1 litre
Ivomec Classic Pour-On for Cattle 2.5 litre
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