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Imaverol is a synthetic, antifungal drug suitable for horses, cattle and dogs. Diluted in water and applied as a gentle wash, it is highly effective against the main types of Dermatophytes which cause ringworm.
Brown-yellow, clear, viscous solution containing 100 mg enilconazole per ml. For cutaneous use after dilution.
Imaverol is a synthetic antimycotic. It is indicated for the treatment of dermatomycoses in cattle, horses and dogs induced by the following pathogenic fungi: Trichophyton verrucosum, Trichophyton mentagrophytes, Trichophyton equinum, Microsporum canis, Microsporum gypseum.
For topical use only.
To be prepared and administered in adequately ventilated surroundings.
The concentrated Imaverol solution should be diluted by adding 1 part to 50 parts of warm water, to provide a 2mg/ml emulsion (0.2 % w/v). Dermatophytes will extend into the hair follicles. Possible crusts must therefore be removed with a hard brush, which has been soaked in the diluted Imaverol emulsion. It is highly recommended that the animal be sprayed entirely at the first treatment so as to reach the subclinical lesions as well.
Depending on the nature of the lesions, cattle should be treated 3 to 4 times at 3-day intervals. The animals should either be washed with the diluted emulsion or the emulsion should be applied to them with a sprayer or high-pressure cleaning unit.
The lesions and surrounding skin should be washed with the diluted emulsion 4 times, at 3-day intervals.
The animals should be washed with the diluted emulsion 4 times, at 3-day intervals. While doing this, one should rub thoroughly in the direction opposite to the hair growth to make sure that the skin is thoroughly wet. For the same reason, it is recommended that long-haired dogs be clipped before treatment.
Alternatively dogs may be dipped thoroughly in a bath containing the prepared emulsion.
For external use only.
The solution must be diluted before use.
Meat: Zero days
Milk: Zero hours
Meat: Zero days
Wear suitable protective clothing including impermeable rubber gloves and safety glasses. If the concentrated solution comes into contact with the skin, remove any contaminated clothing immediately and wash skin generously with soap and water.
In the event of accidental eye exposure, flush eye thoroughly with running water. If irritation persists, seek medical attention. In the event of accidental ingestion, flush mouth with plenty of running water and seek medical advice.
Wash hands after use.
Use during pregnancy and lactation
Laboratory studies in rodents have not produced evidence of embryotoxic or teratogenic effects. This product may be given to pregnant and lactating animals. Care should be taken to ensure Imaverol emulsion is not allowed to contaminate the teats and milk.
None known. Enilconazole as a 2mg/ml emulsion is well tolerated. Supportive treatment as required.
Any unused product and empty containers should be disposed of in accordance with guidance from your local waste regulation authority. Do not allow the product to contaminate streams or water supplies.
For animal treatment only. Keep out of the reach and sight of children.
Do not store above 25 °C.
Keep in an adequately ventilated area.
Keep the bottle in the outer carton.
The shelf life after first opening the immediate packaging is 3 months. Solution which has been diluted should be used within 6 weeks.
100 ml amber glass bottles with a tamper evident child resistant cap.
Enilconazole is a synthetic broad-spectrum antimycotic with a high activity against most of the common dermatophytes and various other fungi and yeasts.
It is a selective inhibitor of ergosterol biosynthesis, an essential component of the cell membrane of fungi and yeasts. This results in irreversible changes which are the origin of the fungicidal effect.
The systemic availability after topical administration of enilconazole in animals is very low. An extensive first-pass metabolism has been demonstrated after oral administration. Tissue residues are almost non-existent and, relatively, are highest in the liver. Enilconazole is extensively metabolised and the main excretion routes are urine and faeces. Excretion in the milk from cattle is very limited.
Imaverol 100mg/ml 1x100ml
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