Hepatosyl Plus Liver Support

Hepatosyl Plus Liver Support
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Plus 50mg » Pack of 60 Capsules
Plus 100mg » Pack of 30 Capsules

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  • Plus 50mg » Pack of 60 Capsules £22.04
  • Plus 100mg » Pack of 30 Capsules £20.94
  • Plus 100mg » Pack of 90 Capsules £62.70
  • Plus 200mg » Pack of 60 Capsules £68.22

Selection of 4 products from

£20.94 to £68.22


Hepatosyl Plus is an extensively used nutritional supplement in veterinary medicine and has been specially developed to aid optimal liver function. Available in fragrant and palatable capsules which can be administered whole or opened and sprinkled onto food. Hepatosyl Plus can support hepatic function in any circumstance where liver function is reduced or liver damage is suspected. This includes before and after general anaesthetic, after possible cases of poisoning or toxin ingestion, or any conditions where a boost for the liver might be required.

Hepatosyl is suitable for Dogs & Cats, as well as many other species. It contains s-adenosylmethionine, silybin (as found in Milk Thistle) and Vitamin E

Feeding Guidelines

Hepatosyl Plus

Recommended daily amount = 18mg/kg/day

Body Weight (kg) 50mg Capsules 100mg Capsules 200mg Capsules
0 - 4 1 Capsule
4 - 7 2 Capsules 1 Capsule
7 - 13 2 Capsules 1 Capsule
13 - 20 3 Capsules
20 - 28 4 Capsules 2 Capsules
28 - 38 3 Capsules
Over 38 4 Capsules

Capsules may be given whole or opened and mixed with food. The Extra small 50mg capsules are specially for cats.

  • Anaesthetic support - administer for one week prior to and following anaesthesia
  • Long-term use - administer once daily for 2-3 months and then reduce to every other day for long-term maintenance

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 9:00am - 5:00pm
  • Sat: 9:00am - 1:00pm
  • Email: [email protected]

All prices include VAT where applicable.

Reviews (23)

Summary of Reviews for Hepatosyl Plus Liver Support

Overall 5
Ease Of Use
Value For Money
Absence Of Side Effects
23 out of 23 (100%) customers would recommend this product.
5 stars (20 reviews)
4 stars (2 reviews)
3 stars (1 reviews)
2 stars (0 reviews)
1 stars (0 reviews)

Only verified purchasers of this product can leave a review.

35 Hepatosyl
Verified Purchase

By on 20 October 2021

My dog has a high liver count and takes these daily. The liver count is still high but I don't know what it would be if hr didn't take the capsules.

Customer recommends this product

55 Health maintenance
Verified Purchase

By on 13 May 2020


Customer recommends this product

55 liver support
Verified Purchase

By on 10 July 2019

excellent product works really well for Booman Thank you

Customer recommends this product

45 Just what I wanted. At almost half the cost of the vets.
Verified Purchase

By on 11 March 2018

Seem to be working well with my little Jack Russell who has been diagnosed with a liver tumour.

Customer recommends this product

55 New customer from uk
Verified Purchase

By on 10 February 2018

Cant comment on how affective yet as not been taking them long. My dog seems fine on these tablets so far. Happy they came in time stated. Don't seem to have any side affects so far.

Customer recommends this product

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Q & A

Below are some recent questions we've received regarding Hepatosyl Plus Liver Support, including answers from our team.

8 March 2022 at 12:52pm

Equivalent dosage

Carol Howarth

  • VioVet customer since 2016
  • From: Cornwall, United Kingdom

Vet recommended using Denamarin 225mg medium dog for my Working Cocker after bloods revealed need. What dosage of Hepatosyl + would be an equivalent, please, as Denamarin has become very difficult to source. Thank you.

  • VioVet Staff

You should follow the doseage according to the packaging guidelines, this will provide the correct amount of the ingredients within. Any use of this supplement outside of the packaging guidelines should only be done alongside advice from your vet.

3 March 2022 at 6:22pm

Hepatosyl plus

Kenneth prowse

Are there any side effects of long term usage, ie 12months

  • VioVet Staff

This is a supplement and classed similarly to food, therefore there are no listed side effects. Pets can react though similarly to how they can react to an intolerance/allergy to a food, such as with diarrhoea/vomiting or skin conditions. However this usually occurs within the first few days of using the supplement if it is going to be an issue. There are no known or listed side effects for long term use of the product.

12 September 2020 at 3:33pm

Liver problems.


Would this be more palatable for my cat than samylin which she will not take at all.
Will it do the same job.

  • VioVet Staff

Yes this product is very similar to Samylin and can be used as an alternative. It is unlikely to be more/less palatable, it does come in capsular form though that is sprinkled into the food. You may find this easier to mix in than the Samylin tablets.

27 July 2020 at 11:28pm


Jane W

My vet recommended Samylin sachets for my elderly cat but he (the cat, not the vet!) seems to know when it has been added to his food and refuses to eat it. I see that Hepatosyl is marketed as palatable. Is it worth trying this instead?

  • VioVet Staff

The capsules that Hepatosyl come in are palatable, however if your cat is fussy then you may still struggle. The two products will work very similarly so it is worth trying. You may find they are easiest given sprinkled into very palatable food, such as wet food or tuna (as long as these are safe for your cat to eat).

28 September 2015 at 5:00pm

What dose to use?

Sophie Crease

  • VioVet customer since 2015
  • From: Leicestershire, United Kingdom

What dose would I need for my boxer. She currently weighs 26.9kg and was diagnosed with liver disease after having chemo treatment. They believe the damage was caused by the steroids. My battle currently is for her to keep food down as she us committing all the time. I read a review on these which gave me hope....

  • VioVet Staff

I would recommend you give 400mg daily (2 of 200mg tablets).

If she is vomiting a lot your vet might be able to offer something to help control this (the most effective drug is prescription only so you need to talk to your vet).

20 August 2015 at 8:46pm

Hepatosyl versus Samylin


My toy poodle is 11 and he has multi organ chronic inflammation. He is currently on samylin but with all his other meds I cannot afford to continue it long term.
Is hepatosyl a good alternative ? It is half the price and from what I can understand he would only need it every other day long term.
If samylin is much better could I give this every other day long term ? He is a 4.6kg.

Many thanks

  • VioVet Staff

The products are very similar and there is very little difference in the ingredients they contain. I am not aware of any scientific trials conducted to compare the two products so it is not possible to say with certainty, but I believe you would be OK to switch to Hepatosyl. You should check with your own vet too.

4 October 2014 at 3:34pm



my dog has been taking hepatosyl,for 3 1/2, months,his liver enzymes are down,but not normal yet,how long can I continue,giving 1, 50mg caps for,can I continue for a long period of time yet,without any side effects,thankyou

  • VioVet Staff

It is recommended to give one capsule daily for 2-3 months then reduce to every other day for long-term maintenance.

4 January 2014 at 3:08pm

Chronic cholecystitis

Ioana Bena

  • VioVet customer since 2009
  • From: Hunedoara, Romania

Is Hepatosyl suitable for the treatment/management of chronic cholecystitis (in a cat that moreover has a chronic kidney failure)?

  • VioVet Staff

Hepatosyl should be helpful for a cat like this. Any problem which puts the liver under strain can potentially be helped. The kidney failure is a complication which is more difficult to take into account. I would not expect the Hepatosyl to have any direct effect on the kidneys. It is important that a cat like this continues to eat and drink regularly and adequately so it is important not to do anything (such as adding medication to food) which significantly puts the cat off eating. However if these basic requirements are not influenced negatively, the Hepatosyl should be fine.

16 December 2013 at 12:53pm

Hepatosyl and milk thistle for liver trouble

Brenda Connor

My miniature schnauzer is on destolit and hepatosyl for a liver bile problem which causes her to have fits occasionally
I have been reading about the benefits of milk thistle and would like to know if it would be ok to take along with the other medications.

  • VioVet Staff

Hepatosyl is designed to take the place of Milk Thistle. Hepatosyl is a standardised and regulated product, containing 3 active
ingredients, one of which is based on the naturally occurring but
randomly variable wild plant. This active ingredient of both products is
the same.

I doubt if it would be unsafe to use both together
because it is pretty much non-toxic, but I also doubt if you would get
any extra benefit. I would continue as you have been.

Answered by Dr. John Cousins BVSc MRCVS

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