UK Registered Veterinary Retailer

Hepatosyl Plus Liver Support

Hepatosyl Plus Liver Support
Plus 50mg » Pack of 60 Capsules
Plus 100mg » Pack of 30 Capsules

Images are for illustration purposes only. Packaging may change from time to time and images on our website may or may not be updated.

  • Plus 50mg » Pack of 60 Capsules £20.99
  • Plus 100mg » Pack of 30 Capsules £20.99
  • Plus 100mg » Pack of 90 Capsules £59.50
  • Plus 200mg » Pack of 60 Capsules £58.00

Selection of 4 products from

£20.99 to £59.50


Hepatosyl Plus is an extensively used nutritional supplement in veterinary medicine and has been specially developed to aid optimal liver function. Available in fragrant and palatable capsules which can be administered whole or opened and sprinkled onto food. Hepatosyl Plus can support hepatic function in any circumstance where liver function is reduced or liver damage is suspected. This includes before and after general anaesthetic, after possible cases of poisoning or toxin ingestion, or any conditions where a boost for the liver might be required.

Hepatosyl is suitable for Dogs & Cats, as well as many other species. It contains s-adenosylmethionine, silybin (as found in Milk Thistle) and Vitamin E

Feeding Guidelines

Hepatosyl Plus

Recommended daily amount = 18mg/kg/day

Body Weight (kg) 50mg Capsules 100mg Capsules 200mg Capsules
0 - 4 1 Capsule
4 - 7 2 Capsules 1 Capsule
7 - 13 2 Capsules 1 Capsule
13 - 20 3 Capsules
20 - 28 4 Capsules 2 Capsules
28 - 38 3 Capsules
Over 38 4 Capsules

Capsules may be given whole or opened and mixed with food. The Extra small 50mg capsules are specially for cats.

  • Anaesthetic support - administer for one week prior to and following anaesthesia
  • Long-term use - administer once daily for 2-3 months and then reduce to every other day for long-term maintenance

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. To find the exact cost of shipping your item, and to see all options available, follow these steps:

  1. Put the items you wish to order in your basket
  2. Proceed to checkout and enter your delivery address, including country
  3. Delivery information including price will automatically update to what is available to you

Delivery of aerosols

Due to restrictions aerosols can't be sent by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

Reviews (21)

Q & A

Below are some recent questions we've received regarding Hepatosyl Plus Liver Support, including answers from our team.

28 September 2015 at 5:00pm

What dose to use?

Sophie Crease

  • VioVet customer since 2015
  • From: Leicestershire, United Kingdom

What dose would I need for my boxer. She currently weighs 26.9kg and was diagnosed with liver disease after having chemo treatment. They believe the damage was caused by the steroids. My battle currently is for her to keep food down as she us committing all the time. I read a review on these which gave me hope....

  • Non-Executive Director

I would recommend you give 400mg daily (2 of 200mg tablets).

If she is vomiting a lot your vet might be able to offer something to help control this (the most effective drug is prescription only so you need to talk to your vet).

20 August 2015 at 8:46pm

Hepatosyl versus Samylin


My toy poodle is 11 and he has multi organ chronic inflammation. He is currently on samylin but with all his other meds I cannot afford to continue it long term.
Is hepatosyl a good alternative ? It is half the price and from what I can understand he would only need it every other day long term.
If samylin is much better could I give this every other day long term ? He is a 4.6kg.

Many thanks

  • Non-Executive Director

The products are very similar and there is very little difference in the ingredients they contain. I am not aware of any scientific trials conducted to compare the two products so it is not possible to say with certainty, but I believe you would be OK to switch to Hepatosyl. You should check with your own vet too.

4 October 2014 at 3:34pm



my dog has been taking hepatosyl,for 3 1/2, months,his liver enzymes are down,but not normal yet,how long can I continue,giving 1, 50mg caps for,can I continue for a long period of time yet,without any side effects,thankyou

  • PHP Developer

It is recommended to give one capsule daily for 2-3 months then reduce to every other day for long-term maintenance.

4 January 2014 at 3:08pm

Chronic cholecystitis

Ioana Bena

  • VioVet customer since 2009
  • From: Hunedoara, Romania

Is Hepatosyl suitable for the treatment/management of chronic cholecystitis (in a cat that moreover has a chronic kidney failure)?

  • Non-Executive Director

Hepatosyl should be helpful for a cat like this. Any problem which puts the liver under strain can potentially be helped. The kidney failure is a complication which is more difficult to take into account. I would not expect the Hepatosyl to have any direct effect on the kidneys. It is important that a cat like this continues to eat and drink regularly and adequately so it is important not to do anything (such as adding medication to food) which significantly puts the cat off eating. However if these basic requirements are not influenced negatively, the Hepatosyl should be fine.

16 December 2013 at 12:53pm

Hepatosyl and milk thistle for liver trouble

Brenda Connor

My miniature schnauzer is on destolit and hepatosyl for a liver bile problem which causes her to have fits occasionally
I have been reading about the benefits of milk thistle and would like to know if it would be ok to take along with the other medications.

  • Non-Executive Director

Hepatosyl is designed to take the place of Milk Thistle. Hepatosyl is a standardised and regulated product, containing 3 active ingredients, one of which is based on the naturally occurring but randomly variable wild plant. This active ingredient of both products is the same.

I doubt if it would be unsafe to use both together because it is pretty much non-toxic, but I also doubt if you would get any extra benefit. I would continue as you have been.