Frusemide (also called furosamide) is a diuretic used to clear excess fluid from the body. Frusemide is particularly helpful in cases of mild, moderate or severe heart failure. When the heart is not able to pump blood around the body as effectively as it should, diuretics help to reduce an unhelpful build up of fluid in the body, making the blood circulation more efficient.
Long term use can be associated with low blood levels of potassium. Where this occurs, potassium supplementation is recommended. Overdose will cause dehydration.
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SUMMARY OF PRODUCT CHARACTERISTICS
Name of THE Veterinary Medicinal Product
Frusemide 40 mg Tablets
Qualitative and Quantitative Composition
Active substance Qualitative composition Quantitative composition Furosemide (Frusemide) 40 mg per tablet
Excipients For a full list of excipients, see section 6.1.
Tablets. White, circular, biconvex, flat-faced tablets with bevelled edges, with F40 on one side and CP or DP on the reverse, and a breakline.
4.1 Target species
Cats and dogs.
4.2 Indications for use, specifying the target species
For the treatment of oedema associated with cardiac insufficiency, renal dysfunction and trauma in cats and dogs. In animals with pulmonary oedema of cardiac origin, combined therapy with other medicinal products may be indicated.
Do not use in animals with acute glomerular nephritis, renal failure with anuria, electrolyte deficiency disease or in animals that have received an overdosage of digitalis. Do not use concurrently with aminoglycoside antibiotics. Do not use in animals weighing less than 4 kg.
Special warnings for each target species
There are no special warnings required for either target species.
Special precautions for use
i. Special precautions for use in animals
Do not exceed the recommended dosage. Therapeutic efficacy may be impaired by increased intake of drinking water. Where the animal’s condition permits, water intake should be restricted during treatment with Frusemide 40 mg tablets.
Monitoring of plasma potassium levels is advisable during periods of prolonged treatment of combined therapy with cardiac glycosides. Potassium supplements may be necessary.
ii. Special precautions to be taken by the person administering the veterinary medicinal product to animals
Wear gloves, or wash your hands immediately after handling the tablets.
4.6 Adverse reactions (frequency and seriousness)
Administration at the recommended dosage level is not normally associated with undesirable effects.
4.7 Use during pregnancy, lactation or lay
Frusemide 40 mg tablets are not contraindicated in pregnant or lactating animals.
4.8 Interaction with other medicinal products and other forms of interaction
Concurrent administration with corticosteroids may increase the risk of hypokalaemia. Concurrent administration with aminoglycoside antibiotics may result in ototoxicity. Concurrent administration with cephalosporin antibiotics may result in nephrotoxicity. Concurrent administration with digoxin enhances the cardiac glycoside. Concurrent administration with sulphonamide antibacterials may result in sulphonamide allergy.
4.9 Amounts to be administered and administration route
For oral administration only. Cats and dogs: Dosage up to 5 mg/kg bodyweight, or one tablet, per 8 kg bodyweight, one to two times daily with an interval of 6 - 8 hours between administrations. For animals weighing between 4 and 8 kg, one half of one tablet should be administered. The tablets may be divided by breaking along the score line. For maintenance, the dosage should be reduced to 1 - 2 mg/kg per day. Not to be used in animals under 4 kg bodyweight.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Transitory deafness may occur in animals administered the product at doses higher than those recommended. Cardiovascular side effects may occur in weak and old animals following overdosage. Excessive doses can lead to hypovolaemia and decompensate renal function. Management of signs of overdosage is symptomatic.
4.11 Withdrawal periods
Pharmacotherapeutic group: Furosemide
ATC Vet Code: QC03CA01
5.1 Pharmacodynamic properties
The tablets contain Furosemide. Furosemide is a potent loop diuretic with a rapid action.
5.2 Pharmacokinetic properties
Furosemide inhibits electrolyte resorption in the proximal and distal renal tubules and in the ascending Loop of Henle. Excretion of sodium, potassium and chloride ions is enhanced, and also water excretion is enhanced. Furosemide has no effect on carbonic anhydrase. Diuretic activity begins one hour after oral administration and continues for four hours. The potency ensures diuretic action even when renal function is poor. Loop diuretics may cause severe potassium loss.
6.1 List of excipients
Maize starch Pregelatinised starch Magnesium stearate Lactose monohydrate Water, purified
Shelf life of the veterinary medicinal product as packaged for sale: 4 years. 6.4 Special precautions for storage
Do not store above 25°C. Protect from light.
6.5 Nature and composition of immediate packaging
White polypropylene containers with low density polyethylene, push fit, tamper evident caps, containing 250 or 1000 tablets. Not all pack sizes may be marketed.
6.6 Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products, if appropriate
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
MARKETING AUTHORISATION HOLDER
Dechra Limited Snaygill Industrial Estate Keighley Road Skipton North Yorkshire BD23 2RW United Kingdom
DATE OF FIRST AUTHORISATION
21 May 2003
DATE OF REVISION OF THE TEXT
29 September 2016
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Below are some recent questions we've received regarding Frusemide (Furosamide) Tablets for Dogs & Cats, including answers from our team.
If I'm ordering more than 1 product which needs a prescription do I need to ask my vet for 2 separate prescriptions or can 2 items go on the one prescription. My vet charges for prescriptions so I would prefer if possible to put 2 products on 1 prescription and pay for the one prescription if the vet is agreeable.
Charging for prescriptions is up to your vet. Some vets are very helpful, some are deliberately unhelpful. Your vet is able to put as many drugs onto one prescription as he/she chooses, but some prefer to write out separate prescriptions per drug (one can wonder why!). They can also prescribe as much or as little as they think is reasonable on one prescription. Up to 6 months worth is the usual guideline, but again this is not legally defined and so is down to your vet.
One of my cats is on a 10mg tablet of Frusemide daily. I have to use a pill cutter to chop in half to give him half in the morning and half in the evening . Firstly do you sell 10mg tablets and secondly is the 20mg tablet large enough to be cut into 4? Thanks.
We do not sell 10mg tablets. 20mg frusemide tablets are very small, so quartering would be difficult. Normally for a 5mg dose, I would recommend using a liquid form of frusemide. This can then be measured very easily by syringe and a few drops of the liquid added to food. Frusol is an example, available in 4mg/ml solution, so 1 .25mls would be the dose here.
Today I have placed an order for FRUSEMIDE. The invoice shows 1 tablet at 03 pence. I need a box of 50 x 40 mg.
Is this item available and if so can my order be changed ?
Thank you for your question and order. We sell these tablets per tablet as some customers do not want a whole box. We have changed your order to 50 tablets, which will be dispatched as a whole box. I hope this helps answer your question. There is a balance payable for the extra 49 tablets, which we will send you a Paypal request for.