Estimated dispatch within 24 working hours.
Frusecare is the UK veterinary licensed form of frusemide made by Animalcare. It is used to reduce fluid accumulation in the body (oedema and vascular) secondary to heart, kidney and liver problems, or in certain types of injury.
Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication.
Company name: Animalcare Limited
Address: Common Road
York YO19 5RU
Telephone: 01904 487687
Fax: 01904 487611
Email: [email protected]
White, circular, biconvex, flat-faced tablets with bevelled edges, breakline and embossed F40 on one face, CP or DP on the reverse. Each tablet contains Frusemide 40 mg (Furosemide).
Frusecare tablets are for use in cats and dogs only, for the treatment of oedema associated with cardiac insufficiency, renal dysfunction and trauma. In animals with pulmonary oedema of cardiac origin, combined therapy with other medicinal products may be indicated. Furosemide is a potent diuretic with an onset of activity normally within 1 hour of administration and a duration of activity of approximately 4 hours.
For oral administration only. Dogs and cats above 4 kg bodyweight:
Dosage up to 5mg/kg bodyweight, or one Frusecare tablet per 8 kg bodyweight, 1 to 2 times daily with an interval of 6 to 8 hours between administrations.
For animals weighing between 4 and 8 kg, one half of one tablet should be administered. The tablets may be divided by breaking along the score line. For maintenance, the dosage should be reduced to 1-2mg/kg per day.
Do not use in animals weighing less than 4 kg.
Do not use in animals with acute glomerular nephritis, renal failure with anuria, electrolyte deficiency disease or in animals that have received an overdosage of digitalis. Do not use concurrently with aminoglycoside antibiotics or corticosteroids.
Therapeutic efficacy may be impaired by increased intake of drinking water. Where the animal's condition permits, water intake should be restricted during treatment with Frusecare tablets.
Monitoring of plasma potassium levels is advisable during periods of prolonged treatment of combined therapy with cardiac glycosides. Potassium supplements may be necessary.
Frusecare tablets may be used in pregnant and lactating animals.
Concurrent administration with aminoglycoside antibiotics may result in ototoxicity. Concurrent administration with cephalosporin antibiotics may result in nephrotoxicity. Concurrent administration with sulphonamide antibacterials may result in sulphonamide allergy. Concurrent use of corticosteroids may increase the risk of hypokalaemia.
If you notice any serious effects of other effects not mentioned in this datasheet, please inform your veterinary surgeon.
Operator warnings: Wear gloves or wash hands immediately after handling the tablets.
General precautions: For animal treatment only. Keep out of the reach and sight of children.
Do not store above 25oC. Protect from light.
Disposal: Dispose of unused product and empty containers in accordance with guidance from your local waste regulation authority.
Plastic containers of 1,000 tablets.
Do not use after the expiry date stated on the label.
To be supplied only on veterinary prescription.
UK authorised veterinary medicinal product.
All prices include VAT where applicable.
SUMMARY OF PRODUCT CHARACTERISTICS
Name of THE Veterinary Medicinal Product
Frusecare 40 mg Tablets
Qualitative and Quantitative Composition
Each tablet contains 40 mg Frusemide (Furosemide).
For a full list of excipients, see section 6.1.
Tablets. White, circular, biconvex, flat-faced tablets with bevelled edges and a breakline.
4.1 Target species
Cats and dogs.
4.2 Indications for use, specifying the target species
For the treatment of oedema associated with cardiac insufficiency, renal dysfunction and trauma in cats and dogs.
In animals with pulmonary oedema of cardiac origin, combined therapy with other medicinal products may be indicated.
Do not use in animals with acute glomerular nephritis, renal failure with anuria, electrolyte deficiency disease or in animals that have received an overdosage of digitalis.
Do not use concurrently with aminoglycoside antibiotics.
Do not use in animals weighing less than 4 kg.
Special warnings for each target species
There are no special warnings required for either target species.
Special precautions for use
i. Special precautions for use in animals
Do not exceed the recommended dosage.
Therapeutic efficacy may be impaired by increased intake of drinking water. Where the animal’s condition permits, water intake should be restricted during treatment. Monitoring of plasma potassium levels is advisable during periods of prolonged treatment of combined therapy with cardiac glycosides. Potassium supplements may be necessary.
ii. Special precautions to be taken by the person administering the veterinary medicinal product to animals
Wear gloves, or wash your hands immediately after handling the tablets.
iii. Other precautions
4.6 Adverse reactions (frequency and seriousness)
Administration at the recommended dosage level is not normally associated with undesirable effects.
4.7 Use during pregnancy, lactation or lay
Not contraindicated in pregnant or lactating animals.
4.8 Interaction with other medicinal products and other forms of interaction
Concurrent administration with corticosteroids may increase the risk of hypokalaemia.
Concurrent administration with aminoglycoside antibiotics may result in ototoxicity.
Concurrent administration with cephalosporin antibiotics may result in nephrotoxicity.
Concurrent administration with digoxin enhances the cardiac glycoside.
Concurrent administration with sulphonamide antibacterials may result in sulphonamide allergy.
4.9 Amounts to be administered and administration route
For oral administration only. Cats and dogs:
Dosage up to 5 mg/kg bodyweight, or one tablet, per 8 kg bodyweight, one to two times daily with an interval of 6 - 8 hours between administrations.
For animals weighing between 4 and 8 kg, one half of one tablet should be administered. The tablets may be divided by breaking along the score line.
For maintenance, the dosage should be reduced to 1 - 2 mg/kg per day.
Not to be used in animals under 4 kg bodyweight.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Transitory deafness may occur in animals administered the product at doses higher than those recommended.
Cardiovascular side effects may occur in weak and old animals following overdosage.
Excessive doses can lead to hypovolaemia and decompensate renal function.
Management of signs of overdosage is symptomatic.
4.11 Withdrawal periods
Pharmacotherapeutic group: Furosemide ATC Vet Code: QC03CA01
5.1 Pharmacodynamic properties The tablets contain Furosemide. Furosemide is a potent loop diuretic with a rapid action.
5.2 Pharmacokinetic properties
Furosemide inhibits electrolyte resorption in the proximal and distal renal tubules and in the ascending Loop of Henle. Excretion of sodium, potassium and chloride ions is enhanced, and also water excretion is enhanced. Furosemide has no effect on carbonic anhydrase. Diuretic activity begins one hour after oral administration and continues for four hours. The potency ensures diuretic action even when renal function is poor. Loop diuretics may cause severe potassium loss.
6.1 List of excipients
Maize starch Pregelatinised maize starch Magnesium stearate Lactose monohydrate
There are no known incompatibilities.
Shelf life of the veterinary medicinal product as packaged for sale: 4 years.
6.4 Special precautions for storage
Do not store above 25°C. Protect from light.
6.5 Nature and contents of immediate packaging
Polypropylene containers containing 1000 white, circular, biconvex, flat-faced tablets with bevelled edges, a breakline and which are embossed F40 on one face, CP or DP on the reverse.
6.6 Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products, if appropriate
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
MARKETING AUTHORISATION HOLDER
Dechra Limited Snaygill Industrial Estate Keighley Road Skipton North Yorkshire BD23 2RW
DATE OF FIRST AUTHORISATION
13 May 1999
DATE OF ANY REVISION OF THE TEXT
Approved: 03 November 2016
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